<div class="text-justify">Describo información sobre la función de la niacina o ácido nicotínico en disminuir los niveles de lípidos en la sangre (efecto hipolipemiante). También comento sobre la pelagra, una enfermedad que se manifiesta cuando hay deficiencia de la vitamina en el organismo, y finalmente sobre su toxicidad cuando se consumen altas dosis.</div><p></p>

<center>https://images.hive.blog/DQmeLuZNFgJUSy7oCtFjBURG6jZQZbkuhKAzm7KNyyfWKoL/01.jpg</center>

<center><iframe width="560" height="315" src="https://www.youtube.com/embed/OHpgQRULUf0" title="YouTube video player" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" allowfullscreen></iframe></center>

<center>REFERENCIAS BIBLIOGRÁFICAS</center><p></p>

<div class="text-justify"><a href="https://doi.org/10.1016/0003-9861(55)90070-9">Altschul, R.; Hoffer, A. & Stephen, J. D. 1955. Influence of nicotinic acid on serum cholesterol in man. Archives of Biochemistry and Biophysics. 54 (2): 558-559.</a></div><p></p>

<div class="text-justify"><a href="https://www.sciencedirect.com/book/9780128029657/the-vitamins">Combs, G. F. Jr. & McClung, J. P. 2017. The vitamins. Fundamental aspects in nutrition and health. (5th ed.). UK-USA: Academic Press.</a></div><p></p>

<div class="text-justify"><a href="https://doi.org/10.1146/annurev.pharmtox.48.113006.094746">Gille, A.; Bodor, E. T.; Ahmed, K. & Offermanns, S. 2008. Nicotinic acid: pharmacological effects and mechanisms of action. Annual Review of Pharmacology and Toxicology. 48: 79-106.</a></div><p></p>

<div class="text-justify"><a href="https://doi.org/10.1016/bs.afnr.2017.11.003">Kirkland, J. B. & Meyer-Ficca, M. L. 2018. Niacin (chapter three). In: Advances in food and nutrition research. New research and developments of water-soluble vitamins. Volume 83. USA/UK: Academic Press.</a></div><p></p>

<div class="text-justify"><a href="https://doi.org/10.1056/nejm199908123410707">Knopp, R. H. 1999. Drug treatment of lipid disorders. The New England Journal of Medicine. 341 (7): 498-511.</a></div><p></p>

<div class="text-justify"><a href="https://booksmedicos.org/harper-bioquimica-ilustrada-29e-pdf/">Murray, R. K.; Bender, D. A.; Botham, K. M.; Kennelly, P. J.; Rodwell, V. W. & Weil, P. A. 2013. Harper. Bioquímica ilustrada. (29na. ed.). México: McGraw-Hill Interamericana Editores, S.A. de C.V.</a></div><p></p>

<div class="text-justify"><a href="https://www.nhmrc.gov.au/about-us/publications/nutrient-reference-values-australia-and-new-zealand-including-recommended-dietary-intakes">NHMRC-MoH (Australian National Health and Medical Research Council-New Zealand Ministry of Health). 2006. Nutrient reference values for Australia and New Zealand. Including recommended dietary intakes. Canberra, Australia: National Health and Medical Research Council. ISBN 1864962437.</a></div><p></p>

<center>CRÉDITOS</center><p></p>

<center>----------Imágenes----------</center><p></p>

<sub><div class="text-justify">Amedeo John Engel Terzi (<a href="https://commons.wikimedia.org/wiki/File:A_girl_in_the_London_Asylum_suffering_from_chronic_pellagra._Wellcome_V0022633.jpg">Wikimedia Commons</a>) CC BY 4.0.</div></sub><p></p>

<sub><div class="text-justify">Amedeo John Engel Terzi (<a href="https://commons.wikimedia.org/wiki/File:A_woman_suffering_from_chronic_pellagra_with_dermatitis_on_h_Wellcome_V0022634.jpg">Wikimedia Commons</a>) CC BY 4.0.</div></sub><p></p>

<sub><div class="text-justify">Amedeo John Engel Terzi (<a href="https://commons.wikimedia.org/wiki/File:Dermatitis_on_the_back_of_a_man%27s_neck_caused_by_chronic_pel_Wellcome_V0022635.jpg">Wikimedia Commons</a>) CC BY 4.0.</div></sub><p></p>

<sub><div class="text-justify">Center for Disease Control and Prevention (<a href="https://commons.wikimedia.org/wiki/File:PHIL_3757_lores.jpg">Wikimedia Commons</a>) dominio público.</div></sub><p></p>

<sub><div class="text-justify">Vikash Paudel & Deepa Chudal (2020) (<a href="http://dx.doi.org/10.11604/pamj.2020.36.219.24806">Pan African Medical Journal</a>) CC BY 4.0.</div></sub><p></p>

<sub><div class="text-justify">Herbert L. Fred, MD, Hendrik A. van Dijk (<a href="https://commons.wikimedia.org/wiki/File:Pellagra2.jpg">Wikimedia Commons</a>) CC BY-SA 3.0.</div></sub><p></p>

<sub><div class="text-justify">Benjah-bmm27 (<a href="https://commons.wikimedia.org/wiki/File:L-tryptophan-2D-skeletal.png">Wikimedia Commons</a>) dominio público.</div></sub><p></p>

<sub><div class="text-justify">Corinna Kennedy (<a href="https://commons.wikimedia.org/wiki/File:Steroid_Rosacea.jpg">Wikimedia Commons</a>) CC BY-SA 4.0.</div></sub><p></p>

<sub><div class="text-justify">James Heilman, MD (<a href="https://commons.wikimedia.org/wiki/File:EMminor2010.JPG">Wikimedia Commons</a>) CC BY 3.0.</div></sub><p></p>

<sub><div class="text-justify">BruceBlaus (<a href="https://commons.wikimedia.org/wiki/File:Blausen_0012_AdiposeTissue-es.png">Wikimedia Commons</a>) CC BY-SA 4.0.</div></sub><p></p>

<sub><div class="text-justify">TLECOATL ZYANYA (<a href="https://commons.wikimedia.org/wiki/File:Dislipidemias1.jpg">Wikimedia Commons</a>) CC BY-SA 4.0.</div></sub><p></p>

<sub><div class="text-justify">Scientific Animations (<a href="https://commons.wikimedia.org/wiki/File:Vasodilation.jpg">Wikimedia Commons</a>) CC BY-SA 4.0.</div></sub><p></p>

<sub><div class="text-justify">Retailleau, P., Colloc'H, N., Prange, T. (<a href="https://commons.wikimedia.org/wiki/File:1r4u.jpg">Wikimedia Commons</a>) CC BY 4.0.</div></sub><p></p>

<sub><div class="text-justify">Li <em>et al</em>. (2017) (<a href="https://doi.org/10.1371/journal.pone.0177877:">PLoS ONE</a>) CC BY 4.0.</div></sub><p></p>

<sub><div class="text-justify">Scientific Animations (<a href="https://commons.wikimedia.org/wiki/File:3D_medical_animation_still_of_Type_One_Diabetes.jpg">Wikimedia Commons</a>) CC BY-SA 4.0.</div></sub><p></p>

<sub><div class="text-justify">Mikael Häggström (<a href="https://commons.wikimedia.org/wiki/File:Liver_(transparent).png">Wikimedia Commons</a>) dominio público.</div></sub><p></p>

<sub><div class="text-justify">Database Center for Life Science (<a href="https://commons.wikimedia.org/wiki/File:Liver_01_anterior_view.png">Wikimedia Commons</a>) CC BY-SA 2.1 JP.</div></sub><p></p>

<div class="text-justify">Imágenes modificadas en CorelDRAW X8. Otras imágenes en el video, no acreditadas, fueron elaboradas por el autor con los programas Adobe Illustrator CC 2015, Aurora 3D Animation Maker y CorelDRAW X8.</div><p></p>

<center>----------Música----------</center><p></p>

<sub><div class="text-justify"> Chicken - Monplaisir (<a href="https://www.freemusicarchive.org/music/Monplaisir/American_Dreams_Soundtrack/Monplaisir_-_American_Dreams_Original_Soundtrack_-_08_Chicken">Free Music Archive</a>) dominio público.</div></sub><p></p>

<center>----------Video----------</center><p></p>

<div class="text-justify">Creado por el autor con el software Vegas Pro 15.0.</div>
<p></p>
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