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[Pixabay](https://pixabay.com/photos/hand-hyperhidrosis-sweating-1502242/)
Hyperhidrosis is a medical condition characterized by excessive activity of the sweat glands. This medical condition is characterized by hyperhidrosis, which is the production of sweat beyond what is necessary for thermoregulation. It can manifest in different regions of the body, such as the palms, soles, and axillae.
The outcome is an abnormal amount of sweating that is not linked to physical activity, environmental temperature, or any other customary stimuli. Frequently impacted areas of the anatomy encompass the palmar surfaces, axillary regions, plantar surfaces, thoracic region, cranium, and facial region. This last type of excessive sweating is known as craniofacial hyperhidrosis. Craniofacial hyperhidrosis can have a significant impact on an individual's social life and self-perception, leading them to avoid social situations and interactions.
Hyperhidrosis is not considered a significant health risk for the majority of individuals. Nevertheless, the experience can be distressing and socially awkward, ultimately impeding one's overall well-being.
Secondary hyperhidrosis refers to the condition of excessive sweating that is associated with a specific underlying cause, such as menopause, Parkinson's disease, hypoglycemia, or hyperthyroidism. Primary hyperhidrosis is characterized by the occurrence of excessive sweating without a discernible underlying cause. Secondary hyperhidrosis may arise due to particular medications, infections, or fundamental medical conditions. The effective management of excessive sweating in secondary hyperhidrosis necessitates the identification and treatment of its underlying cause.
The aetiology of this disorder remains incompletely comprehended. It is postulated that the aforementioned phenomenon is associated with a malfunction in the operations of the sympathetic nervous system, which regulates the body's response to stress and serves as its homeostatic mechanism. The influence of genetics cannot be discounted. Individuals with primary hyperhidrosis exhibit excessive sweating due to the activation of sweat glands by signals originating from the brain, despite the absence of conditions necessitating the cooling effects of sweat.
Regarding the management of the disorder, the antiperspirant suggested by the internist is a frequently utilized initial strategy. Anticholinergic medications are recognized for their ability to impede the transmission of electrical impulses that stimulate the sweat glands. Beta-blockers, a class of pharmaceuticals that conceal the physiological symptoms of anxiety, are occasionally recommended by medical professionals. In certain instances, individuals may elect to undergo a thoracic sympathectomy, an endoscopic surgical procedure that involves the division of specific nerves linked to perspiration.
The administration of Botox has been observed to attenuate nerve impulses that are correlated with perspiration. The aforementioned is the nomenclature of a protein that can be administered via injection and is derived from botulinum toxin, a substance that possesses neurotoxic properties. Botox injections have become a prevalent method for treating primary hyperhidrosis in cases where topical therapies have proven ineffective.
[Wikipedia](https://commons.wikimedia.org/wiki/File:Excessive_sweating_disease.jpg)
The mechanism of action of the treatment involves the inhibition of nerve signals that stimulate the activation of sweat glands. The manifestation of outcomes following Botox injections for hyperhidrosis typically requires a duration of three to four days. The duration of the outcomes of the treatment can vary up to half a year, contingent upon the individual and the specific region of the body that was addressed.
As per the findings of the International Hyperhidrosis Society, individuals who undergo Botox injections observe a reduction of over 85% in the occurrence of hyperhidrosis. Adverse effects associated with the therapy may encompass discomfort, inflammation, and contusion in the area where the substance was administered. While Botox is commonly employed to treat various forms of hyperhidrosis, its FDA approval is currently limited to the management of excessive sweating in the underarm region. Utilizing it for anatomical regions beyond its approved indications constitutes an off-label application.
In the event that antiperspirant proves ineffective, consulting with an internist can provide insight into potential next steps such as oral medication, Botox injections, or surgical intervention. It is imperative to acknowledge that Botox injections can elicit adverse reactions and may not be universally applicable. It is advisable to consult a healthcare professional prior to selecting a hyperhidrosis treatment.
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- Hyperhidrosis - Symptoms and causes. (2022, September 16). Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/hyperhidrosis/symptoms-causes/syc-20367152
- Botox injections one way to treat hyperhidrosis sweating. (n.d.). Botox Injections One Way to Treat Hyperhidrosis Sweating | UCLA Health. https://www.uclahealth.org/news/botox-injections-one-way-treat-hyperhidrosis-sweating
- C. (n.d.). Hyperhidrosis: Causes, Symptoms, Treatment & Lifestyle Changes. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/17113-hyperhidrosis
- Excessive sweating (hyperhidrosis). (n.d.). nhs.uk. https://www.nhs.uk/conditions/excessive-sweating-hyperhidrosis/
- Hyperhidrosis: Diagnosis and treatment. (n.d.). Hyperhidrosis: Diagnosis and Treatment. https://www.aad.org/public/diseases/a-z/hyperhidrosis-treatment
- Hyperhidrosis. (2021, August 8). Hyperhidrosis | Johns Hopkins Medicine. https://www.hopkinsmedicine.org/health/conditions-and-diseases/excessive-sweating
- Hyperhidrosis: Symptoms, causes, diagnosis, and treatment. (n.d.). Hyperhidrosis: Symptoms, Causes, Diagnosis, and Treatment. https://www.medicalnewstoday.com/articles/182130
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