ESTUDIO EFECTIVIDAD DE CAMPAÑA NACIONAL DE VACUNACIÓN EN REDUCCIÓN DE LA MORTALIDAD POR COVID-19 EN PERSONAS DE 60 AÑOS Y MAYORES. ARGENTINA. 30 de junio de 2021 (eng/esp) by marriakjozhegp

hive-148441 · @marriakjozhegp · Jul 27 '21

ESTUDIO EFECTIVIDAD DE CAMPAÑA NACIONAL DE VACUNACIÓN EN REDUCCIÓN DE LA MORTALIDAD POR COVID-19 EN PERSONAS DE 60 AÑOS Y MAYORES. ARGENTINA. 30 de junio de 2021 (eng/esp)

# BIBLIOGRAFÍA /  bibliography

https://drive.google.com/file/d/1eaoXm747qSgW_m-nYC4e5Q1L_Hii4IkU/view

Estudio realizado en Argentina para determinar la reducción de la mortalidad en pacientes de 60 años y mas en la estrategia de vacunación.


![image.png](https://images.hive.blog/DQmNPyyn91c2K1gpQFWhY9oW9PhybVnhCjcwxVSYKTFPUw6/image.png)


- Se utilizaron las 3 vacunas disponibles en argentina.

- La primera etapa consistió en un diseño test-negative case control (casos y controles de diagnóstico negativo).
- La segunda etapa fue determinar la letalidad de los paciente que dieron positivo para coronavirus en los test. y se vacunaron.

Este estudio se realizo cuando habían la  circulación predominante de las variantes Alpha, Gamma, y Lambda. Se concluyó que se podía disminuir la mortalidad de la infección con la implementación de la vacunación, que la efectividad de la creación de anticuerpos es menor en personas mayores de 80 años pero aún así hay creación de anticuerpos.

![image.png](https://images.hive.blog/DQmPZ8bT1FncBHvJiwtenvyXtUeKNSptjBGRn6g8rFqVZ5G/image.png)

En los pacientes vacunados con la SPUTNIK V 155.115 pacientes eran positivos para la infección viral activa del coronavirus y de esos pacientes solo un 16.428 falleció por COVID 19

ASTRANZENICA con 109.135 casos positivos  para la infección viral activa del coronavirus y un 15.476 

SINOPHARM 78.239 casos positivos  para la infección viral activa del coronavirus con 11.215 de fallecidos por covid-19

# Efectividad de la mortalidad primera dosis

***SPUTNIK V***

74.9 %
(73.2% - 76.7%)

***ASTRANZENICA***

79.5%
(77.4% - 80.0%)

***SINOPHARM***

61.6%
(55.9% - 66.2%)

# Efectividad de la mortalidad segunda dosis

***SPUTNIK V***

93.3 %
(91.7% - 94.5%)

***ASTRANZENICA***

88.8%
(75.4% - 95.1%)

***SINOPHARM***

84%
(77.9% - 88.0%)

![image.png](https://images.hive.blog/DQmVQsGAk7PpxQnz8KAQvXacmH5rQ2e6BcrfaRdZ2rvdYYg/image.png)


![image.png](https://images.hive.blog/DQmT23JdmYAN3BF2tC6gcQpGQNNdvMDSLdqJMNV7wDuhqfM/image.png)


![image.png](https://images.hive.blog/DQmek26qGywH6iRuZfd9sCQcRdJ1Byy7kmndeSd6mvKb2Wq/image.png)

# Conclusión


***¿El paciente que se vacuna tiene anticuerpos?***
El 95% de los pacientes que reciben la vacuna aumentan los títulos totales de anticuerpos. Y era más efectivo en pacientes jóvenes.

***¿tiene anticuerpos contra el receptor ECA - 2?***
Recuerden que el coronavirus tiene una proteína llamada proteína spike sars cov 2 que se une a los receptores ECA- 2 ( Enzima convertidora de angiotensina 2) para iniciar su infección viral en las células pulmonares.

El 85% de los pacientes tienen anticuerpos contra receptor ECA 2, en predominancia la efectividad de la vacuna que se creo para luchar en contra el coronavirus original vs variantes alfa y delta es 1.3% menos efectiva, y contra la variante beta es 10 veces menor.

***HABIAN ANTICUERPOS NEUTRALIZANTES?***
Crean anticuerpos neutralizantes contra las tres variantes del coronavirus y el virus salvaje pero suelen disminuir su efectividad, la disminución predomina en el ámbito de disminuir contagios y pacientes asintomaticos, no tanto para evitar hospitalizaciones y muertes.

# English

Study carried out in Argentina to determine the reduction of mortality in patients aged 60 years and over in the vaccination strategy.


https://images.hive.blog/DQmNPyyn91c2K1gpQFWhY9oW9PhybVnhCjcwxVSYKTFPUw6/image.png

- The 3 vaccines available in Argentina were used.
- The first stage consisted of a test-negative case control design (negative diagnostic cases and controls).
- The second stage was to determine the lethality of the patients who tested positive for coronavirus in the tests.

This study was conducted when there was the predominant circulation of the Alpha, Gamma, and Lambda variants. It was concluded that the mortality of the infection could be reduced with the implementation of vaccination, that the effectiveness of the creation of antibodies is lower in people over 80 years of age, but there is still the creation of antibodies.

https://images.hive.blog/DQmPZ8bT1FncBHvJiwtenvyXtUeKNSptjBGRn6g8rFqVZ5G/image.png

In patients vaccinated with SPUTNIK V, 155,115 patients were positive for the active viral infection of the coronavirus and of these patients, only 16,428 died of COVID-19

ASTRANZENICA with 109,135 positive cases for the active viral infection of the coronavirus and 15,476

SINOPHARM 78,239 positive cases for the active viral infection of the coronavirus with 11,215 deaths from covid-19

# Effectiveness of first dose mortality

***SPUTNIK V***

74.9%
(73.2% - 76.7%)

***ASTRANZENICA***

79.5%
(77.4% - 80.0%)

***SINOPHARH***

61.6%
(55.9% - 66.2%)

# Effectiveness of mortality second dose

***SPUTNIK V***

93.3%
(91.7% - 94.5%)

***ASTRANZENICA***

88.8%
(75.4% - 95.1%)

***SINOPHARM***

84%
(77.9% - 88.0%)

https://images.hive.blog/DQmVQsGAk7PpxQnz8KAQvXacmH5rQ2e6BcrfaRdZ2rvdYYg/image.png

https://images.hive.blog/DQmT23JdmYAN3BF2tC6gcQpGQNNdvMDSLdqJMNV7wDuhqfM/image.png

https://images.hive.blog/DQmek26qGywH6iRuZfd9sCQcRdJ1Byy7kmndeSd6mvKb2Wq/image.png

# Conclution


***Does the vaccinated patient have antibodies?***
95% of patients who receive the vaccine increase total antibody titers. And it was most effective in young patients.

***Do you have antibodies against the ACE-2 receptor?***
Remember that the coronavirus has a protein called spike sars cov 2 protein that binds to the ACE-2 (Angiotensin Converting Enzyme 2) receptors to initiate its viral infection in lung cells.

85% of patients have antibodies against ACE 2 receptor, predominantly the effectiveness of the vaccine that was created to fight against the original coronavirus vs alpha and delta variants is 1.3% less effective, and against the beta variant is 10 times less .

***WERE NEUTRALIZING ANTIBODIES?***
They create neutralizing antibodies against the three variants of the coronavirus and the wild virus but they tend to decrease their effectiveness, the decrease predominates in the field of reducing infections and asymptomatic patients, not so much to avoid hospitalizations and deaths.

👍 opb, drhueso, babytarazkp, leslieebano, brofund-stem, itsmiessyonpeakd, solominer.stake, meestemboom, modeprator, yggdrasil.laguna, sqube, gangstalking, disneyplus, signup4airdrops, fourwinds, mailfraud, yourmothershouse, williamgarybusey, havanasyndrome, churchlady, aclu, acousticpulses, voiceofgod, baitandswitch, truthmachine, chainletter, fantasyisland, drseuss, tonguetwisters, beardeddragon, hotpotatoeyes, knowmcmouse, cumplayntdesk, dohn8, uglyfacehodl, uglyface, duhmoninsuecas, timedclevadanz, almanjoygotnut, pinkslips, elementofprize, disaintronco, asseenontv, pharolldice, etfonehomeowch, urbeautiful, knowmynipple, crypnwaffles, valpak, ivankabootybar, tosmomatrainin, chezmamatajawk, keepthewang, slaveone, sexiturburgloh, guillotine, tapherthird114, face4me2siton, tugmyuglyboat, facekrookie, kinqrookie, vainhodler, rolzovnodont, inokonknockers, and 164 others

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