Viewing a response to: @mikewick77/disease-x
![440px-Tree_Of_Life_(with_horizontal_gene_transfer).svg.png](https://images.hive.blog/DQmPn5UBfV6iC15u28Yr7JtVKMhc8qV237rc7osiCxasaAU/440px-Tree_Of_Life_(with_horizontal_gene_transfer).svg.png) ![Screenshot_20220105-070342_Samsung Internet Beta_1.jpg](https://images.hive.blog/DQmazzbZH9WZzrb9Gv9nKmYCenhNBFiYRQuZrKB7LpCP2oC/Screenshot_20220105-070342_Samsung%20Internet%20Beta_1.jpg) LUCA Horizontal Gene Transfer 355 Protein Clusters The last universal common ancestor between ancient Earth chemistry and the onset of genetics https://en.m.wikipedia.org/wiki/Last_universal_common_ancestor https://en.m.wikipedia.org/wiki/Organism#Horizontal_gene_transfer https://en.m.wikipedia.org/wiki/Horizontal_gene_transfer The most commonly accepted location of the root of the tree of life is between a monophyletic domain Bacteria and a clade formed by Archaea and Eukaryota of what is referred to as the "traditional tree of life" based on several molecular studies. Research published in 2016, by William F. Martin, by genetically analyzing 6.1 million protein-coding genes from sequenced prokaryotic genomes of various phylogenetic trees, identified 355 protein clusters from amongst 286,514 protein clusters that were probably common to the LUCA. Its genetic code required nucleoside modifications and S-adenosylmethionine-dependent methylations." The results depict methanogenic clostria as a basal clade in the 355 lineages examined, and suggest that the LUCA inhabited an anaerobic hydrothermal vent setting in a geochemically active environment rich in H2, CO2, and iron. .. https://en.m.wikipedia.org/wiki/Organelle#Types https://en.m.wikipedia.org/wiki/Plastid there are only two broad classes of organelles that contain their own DNA, and have originated from endosymbiotic bacteria: Mitochondria: (Eukaryotes) Plastids: (Plants, Algae, Protists) Plastid are considered to be intracellular endosymbiotic cyanobacteria. .. Endosymbiont Virus is a Parasitic Plastid. .. Invertebrate Chloroplast Nucleomorph Apicoplast Symbiont Endotoxin Endosymbiosis Cyanobacteria Plastid like Apicoplast is inside Malaria, Cicadicola inside Cicada, Toxoplasmosis inside Toxoplasma-gondii, Its a Plastid Cyanobacteria. Plastid Cyanobacteria Endosymbiotic in Mammal Mitochondria, without the need for Invertebrate. if an animal, such as a bird, if the Endosymbionts were removed, so would the natrual instincts, such as making a nest. not the Mitochondria Endosymbiots, but the brain ones, its a plant-like Algae, it has a separate memory that can continue memory from animal to animal. some Plastids live in the Brain, others in Mitochondria, depending upon the evolution of species Symbiogenesis. trying to find a link between Cyanobacteria & Mycoplasma. .. Parasites such as Plasmodium and Toxoplasma possess a plastid homologous to the chloroplasts of algae and plants. The Plastid (Apicoplast; Apicomplexan Plastid) is non-photosynthetic and reduced minimal genome, has endosymbiotic ancestry including a circular genome that encodes RNAs and proteins and bacterial biosynthetic pathways. .. Endosymbiotic theories for eukaryote origin https://royalsocietypublishing.org/doi/10.1098/rstb.2014.0330 .. Brain Mitochondrion https://www.sciencedirect.com/topics/medicine-and-dentistry/brain-mitochondrion https://en.m.wikipedia.org/wiki/Glutamic_acid .. Human Mitochondrial Genetics https://en.m.wikipedia.org/wiki/Human_mitochondrial_genetics Mitochondria in Cancer https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7278520/ Existence of Circulating Mitochondria in Human and Animal Peripheral Blood Researchers Find Cell-Free Mitochondria Floating in Human Blood https://www.the-scientist.com/news-opinion/researchers-find-cell-free-mitochondria-floating-in-human-blood--67071 Zombie cancer cells eat themselves to live https://www.sciencedaily.com/releases/2014/04/140405233847.htm
author | mikewick77 |
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permlink | r58pe3 |
category | disease |
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ADAM Protein Adamalysin Crotalus Adamanteus Metalloendopeptidase Proteinase ENZYME: EC 3.4.24.46 Directed Evolution Protein Design Bioengineering Protein Engineering Peptide Synthesis Site-Directed Mutagenesis Artificial Gene Synthesis MEROPS (Database) Wellcome Trust Sanger Institute Neil D Rawlings http://merops.sanger.ac.uk https://en.m.wikipedia.org/wiki/ADAM_(protein) https://en.m.wikipedia.org/wiki/Protein_design https://en.m.wikipedia.org/wiki/Directed_evolution https://en.m.wikipedia.org/wiki/MEROPS .. Control of active liquid crystals with a magnetic field https://www.pnas.org/content/113/20/5498 Active liquid crystals powered by force-sensing DNA-motor clusters https://arxiv.org/pdf/2106.14097 ‘Radiogenetics’ seeks to remotely control cells and genes https://www.rockefeller.edu/news/9091-radiogenetics-seeks-to-remotely-control-cells-and-genes/
author | mikewick77 |
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LUCA Endosymbiont Chimera Virus Meiosis Bacteriome Intracellular Symbionts Meiosis: Its Origin According to the Viral Eukaryogenesis Theory https://www.intechopen.com/chapters/45597
author | mikewick77 |
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![glycorna-1000px.jpg](https://images.hive.blog/DQmbfjvq8c4xNTeakj2rPRGrtDLXNqrKogigSvrsctbcAch/glycorna-1000px.jpg) Mannose Lectin Immune-Signaling Glycosylated RNAs GlycoRNAs Siglecs Siglec-11 Siglec-14 Sialic-Acid N-Azidoacetylmannosamine ManNAz SiaNAz Sialosides vs mRNA-Vaccine Gain-of-Function GOF Fetal-Stem-Cell XMRV Plastid Cyanobacteria Endosymbiont Endosymbiosis Retrovirus .. its almost like Mycoplasma are co-infected with non-motile Alphaproteobacteria, and Cytoplasm/Cytoplasmic Endosymbionts, and mislabeled as a virus. the same way Gram Positive drops a shell to become Gram Negative, then loose another to become Mycoplasma & finally loose all shell & convert into a Mitochondria Endosymbiont Bacteria, Yeast or both at the same time, then Gain of Function using Human Fetus Stem Cells with animal Chimera Symbionts making something like XMRV Virus? like Candidatus, if this is totally dependent upon a host mitochondria, can it be classified as alive, or virus-like? .. Proteobacteria https://courses.lumenlearning.com/microbiology/chapter/proteobacteria/ .. “Candidatus Gortzia shahrazadis”, a Novel Endosymbiont of Paramecium multimicronucleatum and a Revision of the Biogeographical Distribution of Holospora-Like Bacteria https://www.frontiersin.org/articles/10.3389/fmicb.2016.01704/full .. Non-Motile Bacteria https://en.m.wikipedia.org/wiki/Non-motile_bacteria https://en.m.wikipedia.org/wiki/Candidatus Non-Motile Proteobacteria Candidatus Cytoplasm Endosymbiont Endosymbionts of Acanthamoeba Isolated from Domestic Tap Water in Korea https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC2788711/ https://en.m.wikipedia.org/wiki/Glycoprotein .. ![220px-Ms2capsid.png](https://images.hive.blog/DQmY3cgHToa9zPbqDD9eT8fQpVLZqyT6zd3c1F6937eyNH5/220px-Ms2capsid.png) Phi X 174 https://en.m.wikipedia.org/wiki/Phi_X_174 https://en.m.wikipedia.org/wiki/Bacteriophage_MS2 https://en.m.wikipedia.org/wiki/Bacteriophage_Qbeta https://en.m.wikipedia.org/wiki/SV40 https://en.m.wikipedia.org/wiki/Phagosome Bacteriophage flux in endosymbionts (Wolbachia): infection frequency, lateral transfer, and recombination rates https://academic.oup.com/mbe/article/21/10/1981/1025192 Bacteriophage MS2 (Emesvirus zinderi), commonly called MS2, is an icosahedral, positive-sense single-stranded RNA virus that infects the bacterium Escherichia coli. DNA containing three Escherichia coli genes responsible for the metabolism of the sugar galactose into the genome of the Simian Virus. Several scientists feared that bacteria carrying SV40 DNA might escape and cause cancer in people infected. Biochemical Method for Inserting New Genetic Information into DNA of Simian Virus 40: Circular SV40 DNA Molecules Containing Lambda Phage Genes and the Galactose Operon of Escherichia coli closed-circular DNA molecule .. comparing Bacteriophage MS2 & Wolbachia Craig Venter is working with this Endosymbiont Bacteriophage Virus Phi_X_174. Endosymbiont Bacteriophage Virus Gain of Function mRNA all this keeps falling together like its the same thing. Synthetic Virus ΦX174 genome was the first phage to be cloned in yeast, which provides a convenient drydock for genome modifications. Infect PhiX174 Bacteriophage inside Synthia Mycoplasma Laboratorium .. looking back to Garths paper predicting co-infection Mycoplasma lethal outcome, and how Antibiotics defend against Mycoplasma & Malaria, while anti-Malaria drugs cure Covid Virus, Malaria a Protozoa with Apicoplast Endosymbiont of Alga.. what a web of confusion little spider. .. people who have negative reactions to sulfur is an indicator of parasitic detox reaction? same goes with Nitrogen, same kind of thing, but completely different detox reaction. the sulfur triggers the parasites, especially combined with Nician. people use ozone triple Oxygen for medicine, yet Oxygen makes Oxides require Anti-oxidants, to bind by Electron polarity, is this what Nitrogen & Sulfur does, bind to Oxide into Trioxide? Vitamin K2 is Mannose derivative? .. Notable Lipids https://openoregon.pressbooks.pub/biochemistry/chapter/notable-lipids/ Dolichols Dolichol Pyrophosphate Isoprene Units Phosphorylated forms of dolichols play central roles in the N-glycosylation of proteins. This process, which occurs in the endoplasmic reticulum of eukaryotic cells, begins with a membrane-embedded dolichol pyrophosphate. This oligosaccharide contains three molecules of glucose, nine molecules of mannose and two molecules of N-acetylglucosamine. .. Bactrocera Dorsalis has Wolbachia Endosymbiont. Brucellosis is caused by an acid-fast non-motile, gram negative facultative intracellular coccobacillus related to animal (Anaplasma, Bartonella, Rickettsia and Wolbachia) PCR Polymerase Chain Reaction Endosymbiont Diagnostics https://homepages.eawag.ch/~vorburch/Files/Endosymbiont_Diagnostics_HeidiKaech_June2018.pdf https://academicjournals.org/journal/AJMR/article-full-text-pdf/A9A831266842 Bacteriophage Horizontal Gene Transfer Vertical Transmission https://en.m.wikipedia.org/wiki/Horizontal_gene_transfer https://en.m.wikipedia.org/wiki/Vertical_transmission https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4536854/ PCR tests required for Endosymbiont Diagnostics. the first PDF gives the PCR Procedure & second goes deep into the PCR Analysis of Endosymbionts. how many different bacteria or microbes require a PCR test? .. Transformation: Bacteria take up DNA from their environment Conjugation: Bacteria directly transfer genes to another cell Transduction: Bacteriophages (bacterial viruses) move genes from one cell to another .. Cardinium, Wolbachia, Enterobacter, Bacteroidetes https://en.m.wikipedia.org/wiki/Cardinium https://en.m.wikipedia.org/wiki/Wolbachia https://en.m.wikipedia.org/wiki/Enterobacter https://en.m.wikipedia.org/wiki/Bacteroidetes https://en.m.wikipedia.org/wiki/Green_sulfur_bacteria https://en.m.wikipedia.org/wiki/16S_ribosomal_RNA https://en.m.wikipedia.org/wiki/Reverse_Krebs_cycle .. Polymerase chain reaction (PCR) and Flourescence in situ Hybridisation (FISH) commonly used for identification and localization of bacterial endosymbionts in Whitefly Bemisia Tabaci as it harbors one of the highest numbers of endosymbionts. Bemisia Tabaci can acquire and transmit a range of plant viruses, which produce a variety of different symptoms on susceptible plant species. Whitefly Bemisia Tabaci (Hemiptera: Aleyrodidae) is one of the most important virus vectors, transmitting more than four hundred virus species with ssDNA genomes, the majority belonging to begomoviruses (Geminiviridae). Begomovirus function as a suppressor of host gene silencing https://talk.ictvonline.org/ictv-reports/ictv_online_report/ssdna-viruses/w/geminiviridae/392/genus-begomovirus .. how can the same white fly have the most viruses & endosymbionts, at the same time? unless its the same thing. .. THE INTRODUCTION OF THE EXOTIC Q BIOTYPE OF BEMISIA TABACI FROM THE MEDITERRANEAN REGION INTO CHINA ON ORNAMENTAL CROPS https://bioone.org/journals/Florida-Entomologist/volume-89/issue-2/0015-4040(2006)89%5B168:TIOTEQ%5D2.0.CO;2/THE-INTRODUCTION-OF-THE-EXOTIC-Q-BIOTYPE-OF-BEMISIA-TABACI/10.1653/0015-4040(2006)89%5B168:TIOTEQ%5D2.0.CO;2.full Q Biotype (Whitefly) mtCOI Gene Cytochrome Mitochondrially Encoded Cytochrome C Oxidase I Universal DNA Primer Electron Transport Chain Mitochondrial Redox Nitrogen-Sulfur-Oxygen https://en.m.wikipedia.org/wiki/Cytochrome_c_oxidase_subunit_I https://en.m.wikipedia.org/wiki/Electron_transport_chain#Complex_IV DNA primers for amplification of mitochondrial cytochrome c oxidase subunit I from diverse metazoan invertebrates. https://www.mbari.org/wp-content/uploads/2016/01/Folmer_94MMBB.pdf Universal DNA primers for the polymerase chain reaction (PCR) amplification of a 710-bp fragment of the mitochondrial cytochrome c oxidase subunit I gene (COI). Recent discoveries of more than 230 new invertebrate species, comprising new genera, families, classes, orders, and potentially a new phylum, from deep-sea hydrothermal vent and cold-water sulfide or methane seep communities. .. endosymbiots are hacking the mitochondrial matrix redox system between sulfur, nitrogen & oxygen. plant & animal endosymbiont virus are doing the same exact things, blocking gene silencing, misfolding proteins from mitochondria matrix vectors. venom manufactured via endosymbionts manufacture exotic spike protein peptide RNA/DNA folding from inside mitochondria, only detectable via PCR. Q-Biotype Whitefly (Bemisia Tabaci) is the most documented evidence of Mitochondrial Endosymbiont, Bacteriophage & Virus Symbiogenesis. Chimera Symbionts act as a Virus Vector via Mycoplasma Bacteriophage.
author | mikewick77 |
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![embr201439363-fig-0004-m.jpg](https://images.hive.blog/DQmaCMBnGDpUFdXzNNNh53JZTZE8ME2aE14K2h8oy7yMynu/embr201439363-fig-0004-m.jpg) virus is bacteria phage mitochondria parasite by chimera endosymbiont? something like that, seems like phage is endosymbiont. looking at the smallest minimal genome of Bacteriophage, all strains seem to be involved with E.coli. Mycobacterium can hide directly inside the immune system. .. https://en.m.wikipedia.org/wiki/Phagosome Many Mycobacteria, including Mycobacterium tuberculosis and Mycobacterium avium paratuberculosis, can manipulate the host macrophage to prevent lysosomes from fusing with phagosomes and creating mature phagolysosomes. Such incomplete maturation of the phagosome maintains an environment favorable to the pathogens inside it. .. Endosymbiont Bacteriophage Phagosome PhiX174 Angomonas Deanei Escherichia Virus T4 Mitochondria Chaperone Chaperonin HSP60 Cytochrome P450 Heat Shock Protein https://en.m.wikipedia.org/wiki/Angomonas_deanei https://en.m.wikipedia.org/wiki/Chaperonin https://en.m.wikipedia.org/wiki/Chaperone_(protein) https://en.m.wikipedia.org/wiki/Heat_shock_protein https://en.m.wikipedia.org/wiki/Escherichia_virus_T4 https://en.m.wikipedia.org/wiki/Cytochrome_P450 https://en.m.wikipedia.org/wiki/Piwi-interacting_RNA https://en.m.wikipedia.org/wiki/P_element https://en.m.wikipedia.org/wiki/Selfish_genetic_element .. The Bacterium Endosymbiont of Crithidia deanei Undergoes Coordinated Division with the Host Cell Nucleus https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC2932560/ MicroRNA expression by an oncogenic retrovirus https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3286959/ Viruses of protozoan parasites and viral therapy: Is the time now right? https://virologyj.biomedcentral.com/articles/10.1186/s12985-020-01410-1 .. looks like where Symbiont parasites hack mitochondria protein folding, heat resistance like Prion, where the parasites are misfolding RNA/DNA. Phosgene is a biological function in mitochondria. .. MicroRNA Microprocessor Complex Gametocyte Germline Piwi-Interacting RNA P Element looking at the definition of these words, it appears the pathogenic Endosymbionts are directly from Protozoa Alga Plastid. Protozoa Plastids are Invertebrate Endosymbiont mislabeled Bacteriophage & Virus? Endosymbiont components isolated from animals & orhers from hydrothermal vent extremophile Protozoa Endosymbionts, behave as a infectious Bacteriophage allowing many different sea creatures to exhibit heat resistant properties, used as a weapon in humans manifest as different forms of disease. figured the protozoa hypothesises must have been wrong, then stumbled upon Endosymbionts, and the whole idea came back around again. the critters they gathered around the vents werent for the Mycoplasma or Protozoa, but the Endosymbionts within them, then labeled Bacteriophage, and officially labeled cronic disease & Virus. Endosymbiont Bacteriophage infects any bacteria & converts it into a virus host, then hides within bone, brain & mitochondria. .. reverse genetically modified is another name for gain of function? .. its all from Bacteriophage, also known as Endosymbionts, the true identity of a Virus, harvested from Protozoa volcanic sea vents, Protozoa are riddled with Viruses & Endosymbionts that enter the Mitochondria & manufacture mimicking mRNA that misfolds proteins & manufacture spikes, this is the source of cronic disease, cancer & pandemics, otherwise known as Gain of Function. .. Brucella is similar to this symbiont bacteriaphage into mycoplasma. Fungi Algae Endosymbiont is the most powerful. still looking for evidence of Bacteriophage connection to Plastid. i think the mycoplasma can become Endosymbiont within specific species of animals or insects (virus) or when infecting bacteria (bacteriaphage). this is similar to why Malaria from Protozoa Apicoplast, if left untreated, will develop into a virus. Retrovirus & Lentivirus are Plastid Bacteriophage Endosymbionts that can infect Protozoa, E.coli, Mycoplasmas & Mitochondria. venom manufactured via endosymbionts are being used to manufacture exotic spike protein peptide, by protein folding from inside mitochondria, only detectable via PCR. this mitochondria nano pathogen is the very reason mycoplasma is so difficult to cure, this is a bacteriaphage, infects mitochondria & bacteria, including mycoplasma.
author | mikewick77 |
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permlink | r5g1hw |
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d-Mannose Treatment neither Affects Uropathogenic Escherichia coli Properties nor Induces Stable FimH Modifications https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7024335/ d-mannose ranked as the least preferred carbon source to support bacterial metabolism and growth, in comparison with d-glucose, d-fructose, and l-arabinose. Since small glucose amounts are physiologically detectable in urine, we can conclude that the presence of d-mannose is irrelevant for bacterial metabolism .. mannose seems harmless to humans, wrecks house on parasites, like zink does, chemical electric bond to parasites. that is what Nician does at a chemical level, like electricity. Sulfur MSM DMSO helps neutralize the Niacin flush. .. Beyond Shielding: The Roles of Glycans in the SARS-CoV-2 Spike Protein https://pubs.acs.org/doi/10.1021/acscentsci.0c01056 says the DMSO & Sodium together must be heated, but at a certain temperature Sulfur evaporates. but when i add the liquid Nician to DMSO the bottle heats up, like electron reaction. https://en.m.wikipedia.org/wiki/Sodium_methylsulfinylmethylide by heating up everything together will help thicken the consistency, the Mannose floats & Salt sinks, very low heat in a clear class cup, until everything binds together. .. add sea Salt to boiling water until highest boiling point threshold is reached, remove from heat & add Nitrogen & Sulfur, add Mannose once cool. .. Sodium Protonation Deprotonation Redox Molecules Mitochondria Reactive Oxygen Species Oxidant Electrons Reduction Oxidation Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4101632/ Nitric Oxide and Reactive Oxygen Species in the Pathogenesis of Preeclampsia https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4394437/ Dimethyl sulfide protects against oxidative stress and extends lifespan via a methionine sulfoxide reductase A‐dependent catalytic mechanism https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5334523/ The glyco-redox interplay: Principles and consequences on the role of reactive oxygen species during protein glycosylation https://pubmed.ncbi.nlm.nih.gov/33602616/ .. Cysteine (Sulfur/Nitrogen) Acetylcysteine (NAC) Sodium Chloride (Salt) https://en.m.wikipedia.org/wiki/Acetylcysteine .. Redox Molecules of Mitochondria (ROS), Acetylcysteine (NAC) balances the Sodium/Chloride for Glutathione production. NAC is similar to Nician & DMSO. a derivative of plant biomass, but must be exacted at low temperature, otherwise the acid gas medicine will evaporate. .. sugar salt monosaccharides sodium bond glycosidic Glycosidic Bond https://en.m.wikipedia.org/wiki/Glycosidic_bond .. Ammonium Sulfate Glycerol Nitroglycerin Aldehyde Dehydrogenase ALDH2 https://en.m.wikipedia.org/wiki/Ammonium_sulfate https://en.m.wikipedia.org/wiki/Ammonium_sulfate_precipitation https://en.m.wikipedia.org/wiki/Hydride https://en.m.wikipedia.org/wiki/Nitroglycerin https://en.m.wikipedia.org/wiki/Aldehyde_dehydrogenase https://en.m.wikipedia.org/wiki/ALDH2 Ammonium sulfate decomposes upon heating above 250 °C, first forming ammonium bisulfate. Heating at higher temperatures results in decomposition into ammonia, nitrogen, sulfur dioxide, and water. Certain enzymes, the hydrogenase, operate via hydride intermediates. The energy carrier nicotinamide adenine dinucleotide (NAD) reacts as a hydride donor or hydride equivalent.
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![Neorickettsia_risticii_phylogenetic_tree.jpg](https://images.hive.blog/DQmZpHfQmBFmTeR38vhbPQhz3i9XWjURtSLzr7gdZjDijwc/Neorickettsia_risticii_phylogenetic_tree.jpg) Artificial Endosymbiosis Symbiogenesis Auxotrophy Alpha-Proteobacteria Bacteriaphage Mitochondria Endosymbiont Symbiont https://en.m.wikipedia.org/wiki/Auxotrophy Requiring one or more specific substances for growth and metabolism that the parental organism was able to synthesize on its own. Used with respect to organisms, such as strains of bacteria, algae, or fungi, that can no longer synthesize certain growth factors because of mutational changes. .. Brucella Suis Neorickettsia Risticii Detection of the bacterial endosymbiont Neorickettsia in a New Zealand digenean https://pubmed.ncbi.nlm.nih.gov/27461113/ https://en.m.wikipedia.org/wiki/Neorickettsia_risticii .. Metabolism of the Gram-Positive Bacterial Pathogen Listeria monocytogenes https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6699642/ Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6204759/ .. Auxotrophy https://en.m.wikipedia.org/wiki/Auxotrophy Auxotrophic Mutant https://www.sciencedirect.com/topics/neuroscience/auxotrophic-mutant https://en.m.wikipedia.org/wiki/Adenosine .. Adenosine is a direct target for Parasitic Auxotrophy, the body requires this for ATP enzime reactions, and some parasites target this metabolism. minimal genome endosymbionts are called Auxotrophic Mutants. specifically target the Nitrogen & Sulfur bonds in folding Proteins. .. Ebola-Like Hemorrhagic Fever https://en.m.wikipedia.org/wiki/Marburg_virus_disease https://en.m.wikipedia.org/wiki/Alphaproteobacteria .. Engineering yeast endosymbionts as a step toward the evolution of mitochondria https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6243291/ "engineered E. coli strains to survive in the yeast cytosol and provide ATP to a respiration-deficient yeast mutant. In a reciprocal fashion, yeast provided thiamin to an endosymbiotic E. coli thiamin auxotroph. This readily manipulated chimeric system" A genome phylogeny for mitochondria among alpha-proteobacteria and a predominantly eubacterial ancestry of yeast nuclear genes https://pubmed.ncbi.nlm.nih.gov/15155797/ Effects of mycoplasma contamination on phenotypic expression of mitochondrial mutants in human cells https://pubmed.ncbi.nlm.nih.gov/6965101/ .. the target of cancer & virus are mitochondria. mitochondria replacement, hostile takeover, mimicking mRNA into DNA. zombie mitochondria the way mycoplasma will mimic chemicals to induce a chemotherapy like reaction. chemicals that reduce white blood cell formation. .. Mito is our power house Pathogens hijack them Then our body will look for anaerobic respiration for energy. https://en.m.wikipedia.org/wiki/Anaerobic_respiration Anaerobic respiration is respiration using electron acceptors other than molecular oxygen (O2). Although oxygen is not the final electron acceptor, the process still uses a respiratory electron transport chain. Sulfur & Nitrogen are targets for mycoplasmas, disrupting the natrual formation of enzime & protein folding, resulting in the production of Hydrogen Peroxide. mycoplasma is most effective in a low Nitrogen & Sulfur environment, so to disrupt the mitochondria process, even though Mycoplasma requires the Nitrogen Sulfur, this is the only way to bind them, the weak point is identical to the process being exploited. Kidney is only second to the heart in mitochondrial count and oxygen consumption if cancer could be enhanced to a fast progression, would the symptoms be identical to Ebola? MYCOPLASMAS AND CANCER: FOCUS ON NUCLEOSIDE METABOLISM .. DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4816398/ Artificial Mitochondria Nanobioreactors Programmed exosome fusion for energy generation in living cells https://www.nature.com/articles/s41929-021-00669-z https://singularityhub.com/2021/09/21/scientists-created-artificial-mitochondria-that-can-make-energy-for-damaged-cells/ https://en.m.wikipedia.org/wiki/Catechol https://en.m.wikipedia.org/wiki/Sulfonic_acid .. "But thanks to the system’s plug-and-play mode—just pop in your favorite chemical reactants—we now have a new way to control and reprogram a living cell’s life." i want to know how similar mRNA & Gain of Function is. both mRNA vaccines & Gain of Function use Fetus Stem Cell & Mouse DNA? both are transferring mouse Mitochondria Endosymbionts into humans.
author | mikewick77 |
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Symbiotic infracommunities consisting of different inherited endosymbionts with diverse ef fects on their hosts. Interactions in such communities may be complex, as they involve bacteriophages on top of the bacteria-bacteria relations. Such multiple occurrences are widespread and probably play an im portant role in the evolution of symbiotic associations. .. Inherited intracellular ecosystem: symbiotic bacteria share bacteriocytes in whiteflies https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.07-101162 The players in a mutualistic symbiosis: insects, bacteria, viruses, and virulence genes https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC1287993/
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Nanobacteria Nannobacteria Microzyma Pleomorphism Homologous Recombination Zymotic Disease Progenitor Cryptocides https://en.m.wikipedia.org/wiki/Nanobacterium https://en.m.wikipedia.org/wiki/Zymotic_disease https://en.m.wikipedia.org/wiki/Pleomorphism_(microbiology) https://en.m.wikipedia.org/wiki/Homologous_recombination https://en.m.wikipedia.org/wiki/Gammaproteobacteria https://en.m.wikipedia.org/wiki/Coxiella_burnetii https://en.m.wikipedia.org/wiki/Deinococcus_radiodurans https://en.m.wikipedia.org/wiki/Heat_shock_protein https://en.m.wikipedia.org/wiki/Furin .. Pleomorphic bacteria-like structures in human blood represent non-living membrane vesicles and protein particles https://www.nature.com/articles/s41598-017-10479-8 .. Wuethele-Caspe Livingston & Alexander Jackson isolated a highly pleomorphic organism (named Progenitor cryptocides) from the blood of hundreds of cancer patients which also apparently has a virus-like phase and elementary bodies (0·2 µm) visible as small dots under oil immersion. Such bodies were found in both the tumours and culture medium, and after 1 or 2 months were said to evolve into larger mycoplasma-like L forms and then into frank bacterial rods and filaments. Unidentified, antibiotic-resistant, pleomorphic bacteria have also been seen in the blood of patients with various chronic diseases such as lymphomas and cardiovascular disease. In 1946, Livingston published a paper in which she stated she had established that a bacterium was a causative agent in scleroderma. In 1947, she cultured a mycobacteria-like organism in human cancer and, according to her peer-reviewed paper, fulfilled Koch's postulates establishing an apparent cause and effect. In 1949, Livingston was named chief of the Rutgers-Presbyterian Hospital Laboratory for Proliferative Diseases in New Jersey where she continued her cancer research. It was during this time that Livingston formed a lifetime association with Dr. Eleanor Alexander-Jackson of Cornell University. Jackson's specialty was the study of mycobacteria and particularly, the species responsible for tuberculosis. Jackson had developed specific culture media for growing the microbe and a technique for observing it known as the "triple stain" because she felt this microbe wasn't amenable to conventional modes of culturing and microscopy. .. Golden Silkworms in Pandora's Box https://harvard2thebighouse.substack.com/p/understanding-covid-19-and-seasonal TOPICAL BIBLIOGRAPHY OFPUBLISHED WORKS REGARDING THE HEALTH OF VETERANS OF THE PERSIAN GULF WAR REVISION3, AUGUST1999 L. M. Henry G. C. Gray https://gulflink.health.mil/gwv_bib/ .. Mitochondria HIV Virus Assembly & Cancer Progression Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. This gene is thought to play a role in tumor progression. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. .. Diversity and function of arthropod endosymbiont toxins https://www.sciencedirect.com/science/article/abs/pii/S0966842X21001402 Insect Symbiosis: Derivation of Yeast-like Endosymbionts Within an Entomopathogenic Filamentous Lineage https://academic.oup.com/mbe/article/18/6/995/1046919 .. HEK 293 Human Embryonic Kidney Cell https://en.m.wikipedia.org/wiki/HEK_293_cells https://en.m.wikipedia.org/wiki/Plasmid
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Mitochondria Alzheimer Disease Amyloid Beta β-Amyloid Piron .. Amyloid Beta https://en.m.wikipedia.org/wiki/Amyloid_beta Amyloid beta, the core peptide that forms plaques in AD, potentiates tau toxicity and deposition into paired-helical filaments, ultimately conforming neurofibrillary tangles https://www.sciencedirect.com/topics/medicine-and-dentistry/amyloid-beta .. Β-Amyloid Deposits in Young COVID Patients https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4003213 Beta-amyloid deposits found in young patients with COVID-19 https://www.news-medical.net/news/20220125/Beta-amyloid-deposits-found-in-young-patients-with-COVID-19.aspx .. Mitochondria as a Therapeutic Target for the Treatment of Alzheimer’s Disease https://www.sciencedirect.com/science/article/pii/B9780128028100000106 .. Alzheimer’s disease (AD) is the most common cause of dementia in the elderly and is characterized by the accumulation of neurofibrillary tangles and amyloid plaques in the brain, resulting in neuronal and synaptic dysfunction. Buildup of amyloid peptides (Aβ), a major component of amyloid plaques, can adversely affect mitochondria and promote metabolic dysfunction, thereby implicating mitochondria in AD pathogenesis. Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease, leading to a chain reaction akin to a prion infection. The oligomers are toxic to nerve cells. The other protein implicated in Alzheimer's disease, tau protein, also forms such prion-like misfolded oligomers.
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![1280px-Glicoprotein.svg.png](https://images.hive.blog/DQmWTKBvKJfoM5tCpTZ4GamUze6QUmyZE1t2YejGVRgdv9C/1280px-Glicoprotein.svg.png) Glycoprotein https://en.m.wikipedia.org/wiki/Glycoprotein Cysteine S-glycosylation, a new post-translational modification found in glycopeptide bacteriocins https://febs.onlinelibrary.wiley.com/doi/full/10.1016/j.febslet.2011.01.023 In S-glycosylation, a beta-GlcNAc is attached to the sulfur atom of a cysteine residue. bacteriocin secreted by Lactobacillus plantarum KW30, is modified by an N-acetylglucosamine β-O-linked to Ser18, and an N-acetylhexosamine S-linked to C-terminal Cys43. Glycopeptide bacteriocins in Firmicutes, the reputed lantibiotic sublancin, was shown to contain a hexose S-linked to Cys22. .. N-Acetylglucosamine GlcNAc Cysteine Sulfur S-Glycosylation Glycopeptide Bacteriocins Bacteriophage Phage S-linked glycosylation refers to the attachment of oligosaccharides to the sulfur atom of the cysteine. This modification seems to be extremely rare in comparison to other glycosylation events and was first seen in human and bacterial peptides. Cystine is the oxidized dimer form of the amino acid Cysteine. It serves two biological functions: a site of redox reactions and a mechanical linkage that allows proteins to retain their three-dimensional structure. .. https://t.me/DrAriyanaLove/13514 I read all the Covid vaxx patents. They're using mycoplasmas mostly from E. coli, to create the glycoprotein "S" which is the "spike" protein. The mycoplasma is mixed with fungi, plasmids and the DNA of diseased human/animal hybrids, to make these chimeric proteins. The glycoprotein "S" is transfected into parasites eggs, Hydra polyps and worms and they are the vectors used to transfect human cells. You have to kill them and detoxify the body. They are genetically modified, harder to kill and antibiotic resistant. The SARS-CoV-2 spike (S) glycoprotein is coated onto lipid vesicles (S-LV) which resembled virus-like particles (VLPs) and induce infection. .. Vent Tubeworms Sulphur S-Glycoprotein Gammaproteobacteria Endosymbiont the gene knock-out sounds like Endosymbiont, hijack mitochondria protein folding. disease-x parasite is vent tubeworm heat resistant Endosymbiont use Sulfur Glycoprotein to make Piron. so i mixed together the ingredients that will jam or bind up this process. .. naturalnews 2022-01-28 Bombshell: Can vaccine NERVE DAMAGE be REVERSED with this home-grown molecule called sulforaphane? .. ![imgsrv-32.png](https://images.hive.blog/DQmVGkzG8aVCkh4eSUKyX1938DMFMkBHwuNfeiq5zFE18Gm/imgsrv-32.png) Sulforaphane ![imgsrv-31.png](https://images.hive.blog/DQma1mucBkVRCW9amZ9ouxunpRkuBJ1wkA3ridkWKGU6UQf/imgsrv-31.png) Glucoraphanin https://pubchem.ncbi.nlm.nih.gov/compound/Glucoraphanin https://pubchem.ncbi.nlm.nih.gov/compound/Glucoraphanin .. ![METAZOA.jpg](https://images.hive.blog/DQmbfu3oUjmNEdhNndKRQ7RxG7AFwN6i7bnC7WMvABgwZoS/METAZOA.jpg) Metazoa Endosymbiont Bacteriocyte Gammaproteobacteria Partially glucose-capped oligosaccharides are found on the hemoglobins of the deep-sea tube worm Riftia pachyptila https://academic.oup.com/glycob/article/8/7/663/706964?login=false Structural determination of N-linked oligosaccharides found on extracellular hemoglobins of the hydrothermal vent tube worm Riftia pachyptila. The sugar chains were found to consist mainly of high-mannose-type glycans with some structures partially capped by one or two terminal glucose residues. The present study represents the first report of the occurrence of glucose capping of Nlinked carbohydrates in a secreted glycoprotein of a metazoan. Novel Insights on Obligate Symbiont Lifestyle and Adaptation to Chemosynthetic Environment as Revealed by the Giant Tubeworm Genome https://academic.oup.com/mbe/article/39/1/msab347/6454105?login=false Novel Insights on Obligate Symbiont Lifestyle and Adaptation to Chemosynthetic Environment as Revealed by the Giant Tubeworm Genome https://academic.oup.com/mbe/article/39/1/msab347/6454105?login=false Solving a Bloody Mess: B-Vitamin Independent Metabolic Convergence among Gammaproteobacterial Obligate Endosymbionts from Blood-Feeding Arthropods and the Leech Haementeria officinalis https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4684696/ .. Esophageal Glands Mycetomes Bacteriomes Mycetome https://en.m.wikipedia.org/wiki/Bacteriocyte https://en.m.wikipedia.org/wiki/Bacteriome https://en.m.wikipedia.org/wiki/Mycetome .. ![Amino-acid-synthesis-pathways-present-in-the-endosymbiont-of-Trichoplax-sp-H2-The.png](https://images.hive.blog/DQmVEPeF7GJWTaTnsBX1WGJy8YGTWtvs7xKmLAyphGi4E3A/Amino-acid-synthesis-pathways-present-in-the-endosymbiont-of-Trichoplax-sp-H2-The.png) ![Important-cofactor-biosynthesis-pathways-of-the-endosymbiont-The-symbiont-is-able-to.png](https://images.hive.blog/DQmcbv5yNbm2Jy8TKivDw3VgzpwfRBqYeSr9bbTEwG17TRy/Important-cofactor-biosynthesis-pathways-of-the-endosymbiont-The-symbiont-is-able-to.png) ![Screenshot_20220130-193807_Gallery.jpg](https://images.hive.blog/DQmUgiq7zbLsjxn5XE64DUhn1fUzpx2jp145qUkXh5cRzef/Screenshot_20220130-193807_Gallery.jpg) Genome analyses of a placozoan rickettsial endosymbiont show a combination of mutualistic and parasitic traits. Amino acid synthesis pathways present in the endosymbiont of Trichoplax sp. H2. The symbiont’s genome has retained only few pathway genes for de-novo synthesis from metabolic intermediates. Most remarkable is the retained capability to synthesize the essential amino acids lysine and threonine. Important cofactor biosynthesis pathways of the endosymbiont. The symbiont is able to provide the cofactors (a) riboflavin and (b) pyridoxal 5-phosphate (vitamin B6) for the host. (c) The symbiont possesses panC which enables pantothenate synthesis from β-alanine and pantoate but has lost panD for β-alanine synthesis. The latter can be provided by the host via degradation from uracil. .. Symbiont Metabolism: Pantoate Pantothenate Coenzyme A https://en.m.wikipedia.org/wiki/Pantoic_acid https://en.m.wikipedia.org/wiki/Pantothenic_acid https://en.m.wikipedia.org/wiki/Coenzyme_A .. Symbiont Metabolism: Pantoate Pantothenate Coenzyme A ACADM Gene Acyl-CoA Dehydrogenase (IgE) Immunoglobulin E (MCAD) Mast cell activation disorders (MCADD) Medium-chain acyl-coenzyme A dehydrogenase deficiency https://en.m.wikipedia.org/wiki/Medium-chain_acyl-coenzyme_A_dehydrogenase_deficiency https://en.m.wikipedia.org/wiki/Mast_cell#Mast_cell_activation_disorders https://en.m.wikipedia.org/wiki/ACADM https://en.m.wikipedia.org/wiki/Acyl-CoA_dehydrogenase https://en.m.wikipedia.org/wiki/Immunoglobulin_E https://en.m.wikipedia.org/wiki/Basophil .. A mast cell (mastocyte, labrocyte) is a resident cell of connective tissue that contains many granules rich in histamine and heparin. The mast cell is very similar in both appearance and function to the Basophil, another type of white blood cell. Mast cells are activated in response to infection by pathogenic parasites, such as certain helminths and protozoa, through IgE signaling. Histamine is an organic nitrogenous compound involved in local immune responses. Basophil function is inhibited by CD200. Herpesvirus-6, herpesvirus-7, and herpesvirus-8 produce a CD200 homolog which also inhibits basophil function. This suggests that basophils may play a role in the immune response to these viruses. Histamine = Nitrogen Heparin = Sulfur https://pubchem.ncbi.nlm.nih.gov/compound/Heparin-sodium Histidine in Health and Disease: Metabolism, Physiological Importance, and Use as a Supplement https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7146355/ https://en.m.wikipedia.org/wiki/Chondroitin_sulfate
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