SPED
(Spike Protein Endothelial Disease)

Activated Macrophage
Microglia
Neuronophagia
Glial Activation
Metabolic Dysregulation
Oxidative Stress
Endothelium Cells
Neurons Astrocytes
DNA Double-Strand Damage
Lipid Peroxidation

Linked Glycosylation 
Mannose Binding Lectin

Spike Protein (S)
Nucleocapsid Protein (N)

Spike Protein (S)
https://en.m.wikipedia.org/wiki/Coronavirus_spike_protein

N-linked Glycosylation
https://en.m.wikipedia.org/wiki/N-linked_glycosylation

Tumor Protein P53 (TP53)
https://en.m.wikipedia.org/wiki/P53

..

Neurovascular injury with complement activation and inflammation in COVID-19

https://academic.oup.com/brain/article/145/7/2555/6621999

Synergistic Effects of Natural Product Combinations in Protecting the Endothelium Against Cardiovascular Risk Factors

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297466/

https://wmcresearch.substack.com/?utm_source=substack&utm_medium=web&utm_campaign=substack_profile

..

N-linked glycosylation, is the attachment of an oligosaccharide, a carbohydrate consisting of several sugar molecules.

..

N-linked Glycosylation
Glycosylation
Glycosyl
Ethylene Glycol
Antifreeze

..

Covid acts like HIV, autoimmune reactions similar to chemotherapy?

N-linked Glycosylation is missing from long-covid tests.

my theory is N-linked Glycosylation, Mannose conversion.

..

The end products of lipid peroxidation are reactive aldehydes, such as malondialdehyde (MDA) and 4-hydroxynonenal (HNE), the second one being known also as "second messenger of free radicals" and major bioactive marker of lipid peroxidation.

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The efficacy of antioxidant therapy against oxidative stress and androgen rise in ethylene glycol induced nephrolithiasis in Wistar rats

https://journals.sagepub.com/doi/10.1177/0960327114558889

..

finding evidence of Ethylene Glycol  caused Lipid Peroxidation & Stone Formation.

reminds me of the thin blood with black dirt in the blood clots.

the only reason im saying antifreeze is because Ethylene Glycol is connected with Hydrogel, which the Geobacter may be manufacturing.

im struggling tying all of this together, but its just another hypothesis connected to cybernetics.

Ethylene Glycol
Antifreeze
Hydrogel
Biofilm

Lipid Peroxidation
Polymer (Plastic)
Reactive Aldehydes
Malondialdehyde

Lipid peroxidation are reactive aldehydes, such as malondialdehyde (MDA) and 4-hydroxynonenal (HNE).

Malondialdehyde is reactive and mutagenic, found in heated oils.

..

parasite bacteria nanowires fibroin amyloid microfiber microclots, and transmitting a signal from the hydrogel being formed from inside the body.

plastic veins, gmo bacteria cells, antifreeze blood ect..

im getting the impression..

Geobacter mRNA or Genes, put into Nanobe or Incognitus, acting as Phage to Endothelium cells, replacing the original cells, converting into Homunculus or Senescence cells.

..

https://en.m.wikipedia.org/wiki/Immortalised_cell_line

https://en.m.wikipedia.org/wiki/Cellular_senescence

https://en.m.wikipedia.org/wiki/Cortical_homunculus

https://en.m.wikipedia.org/wiki/Vero_cell

..

Endothelium 
Epithelium

Endothelium is a specialized type of Epithelium found in the lining of blood and lymphatic vessels.

![a-Chemical-structure-of-a-supramolecular-hydrogel-and-a-schematic-illustration.png](https://images.hive.blog/DQmQhSMQSwdSzH6GtanygVio7Ma5zJ2yACL4UVCNNcT6JJ4/a-Chemical-structure-of-a-supramolecular-hydrogel-and-a-schematic-illustration.png)

![Chemical-structure-and-stretchability-of-a-hydrogel-A-Reaction-scheme-for-hydrogel.png](https://images.hive.blog/DQmX158CYsTkEtxtaWLmkLtCUWwgZZizNQkrjEix3QrHUau/Chemical-structure-and-stretchability-of-a-hydrogel-A-Reaction-scheme-for-hydrogel.png)

![Chemical-structure-and-stretchability-of-a-hydrogel-A-Reaction-scheme-for-hydrogel_1.png](https://images.hive.blog/DQmTB2yHuWtjEaLCqQC5N3gWSJitq4evaCVgWurENQwWQkG/Chemical-structure-and-stretchability-of-a-hydrogel-A-Reaction-scheme-for-hydrogel_1.png)

Chemical structure and stretchability of a hydrogel. (A) Reaction scheme for hydrogel formation. (B) Three-dimensional structure of a hydrogel, where hydrophobic aggregates (pink spheres) containing PPGDA molecules (blue chains) are connected by hydrophilic PAAc and PMAM chains (green chains). The green diamonds represent covalent bonds.

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PEG (Vaccine)
Polyethylene Glycol

https://en.m.wikipedia.org/wiki/Polyethylene_glycol

PEG (Hydro-gel)
Poly-Propylene Glycol

https://en.m.wikipedia.org/wiki/Polypropylene_glycol

ETO (Plastic)
Ethylene Oxide

https://en.m.wikipedia.org/wiki/Ethylene_oxide

..

Ethylene
https://en.m.wikipedia.org/wiki/Ethylene

Epoxide
https://en.m.wikipedia.org/wiki/Epoxide

Epichlorohydrin
https://en.m.wikipedia.org/wiki/Epichlorohydrin

Triethylenetetramine
https://en.m.wikipedia.org/wiki/Triethylenetetramine

..

![ethylene-oxide-antimicrobial-molecule-laguna-design.jpg](https://images.hive.blog/DQmbAZEu2Zg5uPsaVN15XhAQHi8dmaM3ohYU63rmuU2RvFm/ethylene-oxide-antimicrobial-molecule-laguna-design.jpg)
Ethylene-Oxide

![th-331050346.jpg](https://images.hive.blog/DQmZ9uU2WTEci43dDmFgKj3nEN9TyC4aa15uGRYRtEHp2de/th-331050346.jpg)
Ethylene-Oxide

Ethylene oxide (ETO) is a colorless, sweet-smelling gas most commonly used as a sterilizing agent for medical equipment, commonly used in antifreeze and polyester known as ethylene glycol.

Ethylene appears to have been discovered by Johann Joachim Becher, who obtained it by heating ethanol with sulfuric acid.

Ethylene oxide is industrially produced by oxidation of ethylene in the presence of silver catalyst.

..

How to Remove Ethylene Glycol From Wastewater

Fenton's Reagent produces the top oxidant: OH• radical. Other ways of making hydroxyl radical, such as exposing rutile coated substrate submerged in water film to short wave UV.

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Decomposition of Ethylene Glycol by the Combined Use of Ozone Oxidation and Electrolytic Methods

https://www.tandfonline.com/doi/abs/10.1080/01919519008552214

Degradation of ethylene glycol using Fenton's reagent and UV

https://www.sciencedirect.com/science/article/abs/pii/S004565350000597X?via%3Dihub

..

PEG in the vaccines is near identical to the antifreeze that makes up hydrogel biosensor & amyloid fibroin jumbo blood clots, possibly a result of synthetic nanobe fermentation.

matching up the chemical makeup to understand how to devolve it.

Psychrophilic 
Cold-Loving Microbe
Antifreeze

https://en.m.wikipedia.org/wiki/Psychrophile

..

![DB01213.mol.t_1.png](https://images.hive.blog/DQmd62TA2A1nNJiL4eof4NuYLcQf2q1nEV7a9K6DuKWbphd/DB01213.mol.t_1.png)
Fomepizole (Antizol)

https://www.healthline.com/health/antifreeze-poisoning

An antidote is the first line of treatment for antifreeze poisoning. These include either fomepizole (Antizol) or ethanol. Both drugs can reverse the effects of the poison.

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NAC
Fomepizole
CYP2E1
NAPQI
APAP
Acetaminophen
JNK Inhibition

https://criticalcarenow.com/fomepizole-not-just-for-toxic-alcohol-toxicity/

Use of fomepizole (4-methylpyrazole) for acetaminophen poisoning:

https://pubmed.ncbi.nlm.nih.gov/34785186/

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NAC

https://en.m.wikipedia.org/wiki/Acetylcysteine

NAD

https://en.m.wikipedia.org/wiki/Nicotinamide_adenine_dinucleotide

NMN

https://en.m.wikipedia.org/wiki/Nicotinamide_mononucleotide

Pyrazole

https://en.m.wikipedia.org/wiki/Pyrazole

..

Nicotinamide mononucleotide (NMN) is a nucleotide derived from ribose, nicotinamide, nicotinamide riboside and niacin.

Nicotinamide dinucleotide phosphate (NADPH) oxidase is one of the major sources of ROS production in diabetes. In this study, NAC inhibits NADPH oxidase activation in diabetes and reduces tissue oxidative damage in all organs.

Fomepizole is a member of the class of pyrazoles that is 1H-pyrazole substituted by a methyl group at position 4. It has a role as an antidote, a protective agent and an EC 1.1.1.1 (alcohol dehydrogenase) inhibitor. It derives from a hydride of a 1H-pyrazole.

The pyrazole ring is found within a variety of pesticides as fungicides, insecticides and herbicides.

derivatives of pyrazole are widely used, including celecoxib and similar COX-2 inhibitors, zaleplon, betazole, and CDPPB.

COX inhibitors have been shown to reduce the occurrence of cancers and pre-cancerous growths. 

COX-2 inhibitors have been found to be effective in suppressing inflammatory neurodegenerative pathways, with beneficial results in animal studies for major depressive disorder, as well as schizophrenia, bipolar disorder, and obsessive-compulsive disorder.

Pyrazole derivatives are used for their analgesic, antipyretic, anti-inflammatory (eantipyrine, phenylbutazone, celecoxib), antibacterial, tranquilizing, anticancer, and antidiabetic activities.

Porphobilinogen (pyrrole), is the biosynthetic precursor to many natural products such as heme.

Heme is a precursor to hemoglobin, which is necessary to bind oxygen in the bloodstream. Heme is biosynthesized in both the bone marrow and the liver.

Porphobilinogen (PBG) is an organic compound that occurs in living organisms as an intermediate in the biosynthesis of porphyrins, which include critical substances like hemoglobin and chlorophyll.

Hemoglobin is the iron-containing oxygen-transport metalloprotein present in red blood cells (erythrocytes) of almost all vertebrates.

..

Synthesis Reactions and Medicinal Uses of Pyrazole

https://solutionpharmacy.in/synthesis-reactions-and-medicinal-uses-of-pyrazole/

Cell-friendly inverse opal hydrogels for cell encapsulation, drug and protein delivery, and functional nanoparticle encapsulation

https://patents.google.com/patent/WO2012148684A1/en?oq=WO+2012%2f148684

EDTA Chelation Dissolves the Artificial Intelligence Magnetic Hydrogel Weapon

https://anamihalceamdphd.substack.com/p/edta-chelation-dissolves-the-artificial

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Geobacter 
Microbial Fuel Cell
Bacterial Nanowires 
Microtubule
Cable Bacteria
Biofilm Hydrogel 
Ethylene-Oxide

Microbial nanowires and electroactive biofilms

https://pubmed.ncbi.nlm.nih.gov/29931163/

https://en.m.wikipedia.org/wiki/Geobacter

https://en.m.wikipedia.org/wiki/Microbial_fuel_cell

https://en.m.wikipedia.org/wiki/Bacterial_nanowires

https://en.m.wikipedia.org/wiki/Cable_bacteria

..

A biofilm may also be considered a hydrogel, which is a complex polymer that contains many times its dry weight in water. Biofilms are not just bacterial slime layers but biological systems; the bacteria organize themselves into a coordinated functional community.

..

Ethylene

https://en.m.wikipedia.org/wiki/Ethylene

Some geologists and scholars believe that the famous Greek Oracle at Delphi (the Pythia) went into her trance-like state as an effect of ethylene rising from ground faults.

Ethylene, an early marker of systemic inflammation in humans

https://www.nature.com/articles/s41598-017-05930-9

https://en.m.wikipedia.org/wiki/Xenobiotic

https://en.m.wikipedia.org/wiki/Xenu

https://en.m.wikipedia.org/wiki/DRACO

https://en.m.wikipedia.org/wiki/Quantum_network

..

Xenu is part of Scientologist teachings about extraterrestrial civilizations and alien interventions in earthly events, collectively described as "space opera" by L. Ron Hubbard. 

Hubbard detailed the story in Operating Thetan level III (OT III) in 1967, warning that the "R6 implant" (past trauma) was calculated to kill (by pneumonia) anyone who attempts to solve it.

..

Xeno seems to represent a microbe, the quantum bots i keep going on about, getting close to the identification of this, because of the vaids blood clots.

psychrophilic (cold-loving) microorganism, antifreeze & hydrogel bloodclots.

called Ethylene-Oxide

Pyrazole Fomepizole to bind up the toxic oxidants, EDTA (Nician & Vitamin C) break it apart, actived Caramelization of Honey to target the parasite via opposite electron bonds.

https://wwwnc.cdc.gov/eid/article/21/12/14-1111_article

Parainfluenza virus 5 (PIV5), family Paramyxoviridae, genus Rubulavirus, was previously known as simian virus 5 because of its discovery in primary monkey kidney cells in 1954.

Paramyxoviridae are able to undergo mRNA editing, which produces different proteins from the same mRNA transcript by slipping back one base to read off in a different open reading frame (ORF) due to the presence of secondary structures such as pseudoknots.

..

https://medicaltrend.org/2021/06/28/research-directions-for-development-and-optimization-of-mrna-vaccines/

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Amyloid and Hydrogel Formation of a Peptide Sequence from a Coronavirus Spike Protein

https://pubs.acs.org/doi/10.1021/acsnano.1c10658

Toxin-like peptides in plasma, urine and faecal samples from COVID-19 patients

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772524/

![Heterocycle_compounds-4.jpg](https://images.hive.blog/DQmUqctbs6AP76KUyowhdDPc2SVkq7rtAJHkdDRezoWkCrA/Heterocycle_compounds-4.jpg)
Heterocyclic Compound

https://en.m.wikipedia.org/wiki/Heterocyclic_compound

https://en.m.wikipedia.org/wiki/Pyrrole

https://en.m.wikipedia.org/wiki/Indole

Heme
Hemoglobin
Porphobilinogen

https://en.m.wikipedia.org/wiki/Porphyria

https://en.m.wikipedia.org/wiki/Porphyrin

https://en.m.wikipedia.org/wiki/Chelatase

..

Fenbendazole looks good, has all the important parts.

we have been talking about Fenbendazole a long time, but forgot about it, now it makes more sense.

my newest recipe is Pine Terpinene, DMSO, Niacin & Vitamin C

that makes sense, because what Mannose Binding Lectin & Citric Cycle.

Sulphur, Nitrogen & Oxygen from DMSO, Nicotinic Acid & Ascorbic Acid.. is not the medicine alone, it requires a special kind of.. carbon sugar carbohydrate mannose mannitol polyphenol terpene benzene.

it acts as nano activated charcoal.

thats why i keep going on about caramelization of honey using lemon.

Fenbendazole

![imgsrv-105.png](https://images.hive.blog/DQmb7GXreUosXexiFjk3B9q1h6TmjHG9e4y7UL145Er1sQQ/imgsrv-105.png)

![imgsrv-105_1.png](https://images.hive.blog/DQmcKdPf1p42i32Syq2LxK6MKuvQKh2Hqp3GDiS6rY72PMf/imgsrv-105_1.png)

Polyphenol, Carbon.

Heterocyclic Compound
Pyrrole
Indole

its basically a smaller form of carbon, twisted up with a Nitrogen.

when the parasite eats is like a mouse trap.

it binds to the parasite via electron bonds.

its similar to using frequency therapy, but without the machine, because its using electronic properties.

my recipe does a similar thing, it gives me an mild almost psychedelic effect, i can feel it attacking the fibrosis in my feet, strange twitching & my brain gets triggered.

so until i find it helpful & safe, cant actually recommended doing it, but Fenbendazole & Doxy is close enough, just more expensive.

if its safe & effective, then i want to find a way to make it similar to the Kraft Process of making DMSO & Terpinene from tree pulp.

CST
Crude Sulfate Turpentine
Kraft Process

Terpinene is found in cannabis, is this the reason it is reported to help cure some cancers? its not the CBD, THC or even the THC-a, but the Turpentines?

Terpinene is like Alcohol, Carbon & Sugar, and is naturally bound to Sulphur, found in wood & called Suramin.

but i dont think it really masters the tree, just the tree sugars.

is why tree mushrooms are so medical.

if the medicine is potent enough, wont need enough to wory about a little contamination parts.

i use liquid Pine Terpinene & DMSO, with powdered Niacin & Vitamin C.

they must be heated up gently to combine together.

im just confirming why Fenbendazole is actually working so well, and my round about way to similar results.

Vitamin C acts as an Acidulant to make Oxygen acidic, so it makes the electron bonds.

..

Pyridine Alkaloid
https://www.sciencedirect.com/topics/chemistry/pyridine-alkaloid

it seems the secret ingredient to Fenbendazole & Suramin is, Pyridine Alkaloid, Alkalinized Nitrogen, Nicotinic Acid, Nician or Nicotine.

..

![imgsrv-112.png](https://images.hive.blog/DQmRaskGBVcBwjV2v2tDK7JkkgSbEcDxecD4oSFnfd2EDtj/imgsrv-112.png)
Pyrrole

![imgsrv-111.png](https://images.hive.blog/DQmcYBsVBmo4Bc1jtGWBqALjt39wRJnZhPFvAeNywwabnVV/imgsrv-111.png)
Nicotine

https://en.m.wikipedia.org/wiki/Pyrrole

Nitrogen as an element isn’t created or destroyed outside of a nuclear reaction. So the amount of nitrogen on the planet is basically all we’ll ever have. Nitrogen does exist in various forms, though, and it’s the interconversion between these chemical forms that’s critical for life as we know it. We’re all composed of nitrogen. It’s part of every protein. It’s literally in our DNA. We need to eat nitrogen compounds (e.g., protein) to maintain our bodies, and we get rid of excess, or metabolized, nitrogen in our pee — mostly in the form of a compound called urea but there’s also a small amount of ammonia in pee too. So you could say we consume nitrogen in complex forms (protein, DNA, etc.) and produce nitrogen in simpler forms (urea, ammonia, uric acid). Bacteria and plants consume these simple forms and convert them back into complex forms. In the case of plants this is done using solar energy. There are soil and aquatic bacteria capable of converting nitrogen gas in air into nitrates and nitrites, which can then be used by plants. But for the most part, nitrogen in the air is fairly non-reactive and isn’t consumed by living things.

..

consume nitrogen in complex forms (protein, DNA, etc.) and produce nitrogen in simpler forms (urea, ammonia, uric acid). Bacteria and plants consume these simple forms and convert them back into complex forms. In the case of plants this is done using solar energy.

meaning this is why Pyrazole is so effective against bacteria, because it jams it up, similar to toxic mushroom to the liver.

Edward Riordan 
Ominous Feeling
https://youtu.be/Fo7ulihIo5s

![content_article_profile_image_cefa6edfdb88666dce5361a6d7bdd7e0a6025125_7362.jpg](https://images.hive.blog/DQmaHxuoXVFueETx9C2xMRYtZnGu9pdgNsUncAhN85JeZWj/content_article_profile_image_cefa6edfdb88666dce5361a6d7bdd7e0a6025125_7362.jpg)
Geobacter

![oh54c0ad66.jpg](https://images.hive.blog/DQmbhwyU5vwuBYCvgVtYdmiZiBJaZ1D323Yz9u7zswjJbAC/oh54c0ad66.jpg)
Geobacter

![Screenshot_20221231-011849_YouTube_1.jpg](https://images.hive.blog/DQmUNtTcimDnCTz2RBA9WhAvr8TWVQD5T1BhyBKLHDGt9dS/Screenshot_20221231-011849_YouTube_1.jpg)
Planaria

![maxresdefault-10.jpg](https://images.hive.blog/DQmNXMAb1rCxkja3oquzQGaBR2RCsRpNucGNquQLrcGPrL3/maxresdefault-10.jpg)
Planaria

Geobacter metallireducens was first isolated by Derek Lovley in 1987 in sand sediment from the Potomac River in Washington D.C. The first strain was deemed strain GS-15.

how close is the bio-lab Lyme Rickettsia was first discovered, compared to Potomac River? and who is Derek Lovley? 

Fort Detrick & Potomac River are just a couple miles apart.

..

Derek Lovley
https://www.micro.umass.edu/faculty-and-research/derek-lovley

Supercapacitors based on c-type cytochromes using conductive nanostructured networks of living bacteria.

https://www.micro.umass.edu/faculty-and-research/publications/supercapacitors-based-on-c-type-cytochromes-using-conductive

..

without Derek Lovley discovery, bio-battery cybernetics wouldn't be possible, i think Geobacter origin has a completely different history.

its just more of the same stuff, about using bacteria for cybernetics, straight from a Lovecraft book.

except nobody seems to understand the general idea, or running on a different rabbit hole, if im right, then nobody is going to find a cure chasing the detours.

i think the people having negative reactions, died suddenly, their immune system is not accepting the cybernetic blood reversal.

if its contagious ive got it, this morning my tooth was acting up, so took 5 drops of undiluted clove oil, got in the car & experienced what felt like my leg veins retracting like muscles would.

talking to vax injured people, they cant take antioxidants because he is in a oxidative cascade, it triggers the toxins.

Pyrazole Fomepizole to bind up the toxic oxidants, EDTA (Nician & Vitamin C) break it apart, actived Caramelization of Honey to target the parasite via opposite electron bonds.

but only 1 or 2 out of 3 wont work, its going to take all three angles, bind the toxins, break open the matrix & capture the parasite.

i dont think its nano bots, but quantum bots & a microbe that manufactures hydrogel via bacteria nanowires.

quantum dots already have its own scientific definition, almost identical to quantum bots, the difference is bots (not robots) are a form of demonic spiritual attachment.

is Amyloid in anyway connected to Hydrogel (Bacteria Biofilm)?

Ethylene plus Oxide

Ethylene from deep earth gasses, Oxide from atmosphere Oxygen.

..

my newest hypothesis is how this hydrogel formation is converting the traditional red iron blood into something more like antifreeze.

the vaccines have some kind of chemotherapy effect on the immune system, and people having negative reactions is the immune system rejection of this process, using a GMO Geobacter as the vector.

..

im not exactly sure, but most all extremophiles are archaea? and why are archaea riddled with mysterious unclassified viruses? because all of this makes me suspect the viruses are actually part of the archaea biological function, as carboxysome are data packages to bacteria.

..

![image.png](https://images.hive.blog/DQmQeXkH1m6a2kXS14JTpgvoRuAhmQEU9kTZfoitSyu3AN6/image.png)

see how the red & green lines connect above?

see where it connects to?

and how Archaea have no line of contact?

Mycoplasma Laboratorium was manufactured to digest oil spills.

Methanogen Archaea are found in crude oil, capable of converting it.

Archaea require external sources of Lipids (oil).

https://en.m.wikipedia.org/wiki/Methanogen

https://en.m.wikipedia.org/wiki/Cyclophilin

..

Spike Protein (S) Glycoprotein is the Biomarker, the other one (N) is missing, N-linked Glycosylation.

this makes me suspect the N is "doing something" else, suspect manufacturing hydrogel clots.

Microbial Fuel Cell
N-linked Glycosylation
Geobacter
Archaea
Eukaryotes

..

Plastid
Lipid

Apicoplast
Archaea

Incognitus
Ignicoccus

Lipids of Archaeal Viruses

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461281/

Decoupling of DAMO archaea from DAMO bacteria in a methane-driven microbial fuel cell

https://www.sciencedirect.com/science/article/abs/pii/S004313541630940X?via%3Dihub

Grappling archaea: ultrastructural analyses of an uncultivated, cold-loving archaeon, and its biofilm

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122167/

Archaeal Viruses, Not Archaeal Phages: An Archaeological Dig

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638648/

..

The N-linked glycosylation process occurs in eukaryotes and widely in archaea, but very rarely in bacteria. 

Methanosarcina, Anaeromyxobacter and Geobacter were identified as V-reducing microorganisms. 

V (V)-reducing bacteria and archaea may use different pathways to reduce V (V). 

V-reducing bacteria use NarG and NapA to perform respiratory V (V) reduction.

Methanosarcina may mediate V (V) reduction coupled with anaerobic methane oxidation.

Geobacter species produce higher current densities than any other known organism in microbial fuel cells and are common colonizers of electrodes harvesting electricity from organic wastes and aquatic sediments.

Archaeal actin ortholog, denoted crenactin, was shown to polymerize into a cytoskeletal structure.

Nearly all archaea possess multiple immune defense systems. CRISPR-Cas in particular is near-ubiquitous, especially in hyperthermophiles, as about 90% of sequenced archaea possess at least one CRISPR-Cas locus in their genome.

SM1 Euryarchaeon biofilm architecture of nano-grappling hooks and barb-wire basal structures.

Nanoarchaeum equitans cannot synthesize lipids but obtains them from its host. Its cells are only 400 nm in diameter, making it the smallest known living organism, and the smallest known archaeon.

..

https://en.m.wikipedia.org/wiki/Archaeal_virus

https://en.m.wikipedia.org/wiki/Actin

https://en.m.wikipedia.org/wiki/Proofreading_(biology)

https://en.m.wikipedia.org/wiki/Exonuclease

..

https://en.m.wikipedia.org/wiki/Nanohaloarchaea

https://en.m.wikipedia.org/wiki/Nanoarchaeota

https://en.m.wikipedia.org/wiki/Nanoarchaeum_equitans

https://en.m.wikipedia.org/wiki/Ignicoccus

https://en.m.wikipedia.org/wiki/Alphaproteobacteria

https://en.m.wikipedia.org/wiki/Pseudomonadota

https://en.m.wikipedia.org/wiki/Asgard_(archaea)

https://en.m.wikipedia.org/wiki/TACK

![Screenshot_20221204-215022_Samsung Internet Beta_1.jpg](https://images.hive.blog/DQmXBnqduJkce8vYgxXUhuYJuzPpoa7gqjmeYWTTfDpKeCC/Screenshot_20221204-215022_Samsung%20Internet%20Beta_1.jpg)

![Screenshot_20221204-215038_Samsung Internet Beta_1.jpg](https://images.hive.blog/DQmYY4kZ6bxtxVX7iWcreeHBHtoE1nwi2sCvWZz72ZYhmqt/Screenshot_20221204-215038_Samsung%20Internet%20Beta_1.jpg)

..

if viruses are not alive, how do they mutate to survive?

Do Archaea, Archaeal Viruses, have anything to do with Gain of Function?

reworking the identity of Incognitus as a form if archaea hosted within mycoplasma.

being they are riddled with unclassified viruses, more closely related to animals then bacteria, are extremophiles, have obligate intracellular endosymbiont species that can potentially enter endothelium cell & potentially mitochondria nucleus, hyjack mRNA causing protein misfolding, manufacture amyloid, manufacture microtubule nanotubes into biofilm hydrogel, possibly even manufacture carboxysome misidentified as phage?

nanobots are a stupid idea, grey-goo hypothesis will be done with gmo microbes, not microchips & tiny robots.

nanotubes are microtubules that create create hydrogel via biofilms, amyloid bloodclots may be the result.

..

Plasmids of archaea as possible ancestors of DNA-containing viruses

Тhе kingdom Archaea, as well as Bacteria, belongs to the overkingdom Prokaryota. 

Halophilic archaea isolated from Antarctic saline lakes contain plasmids (pR1SE) that code proteins taking part in the formation of membranes of archaea vesicles. 

Molecular and biological properties of pR1SE and the peculiarity of its interaction with sensitive cells.

The role of structural proteins coded by pR1S in the process of formation of vesicle membrane complex.

Plasmid-containing archaea vesicles model some properties of viruses.

Archaea plasmids can be viewed as possible ancestors of DNA-containing viruses.

A plasmid from an Antarctic haloarchaeon uses specialized membrane vesicles to disseminate and infect plasmid-free cells

The major difference between viruses and plasmids is the mechanism of transferring their genomic information between host cells. 

Archaeal plasmid pR1SE from an Antarctic species of haloarchaea transfers via a mechanism similar to a virus.

The archaeal protein folding machinery is quite similar to that found in eukaryotes, especially in terms of shared components like chaperones. 

These proteins have peptidyl prolyl isomerase activity, which catalyzes the isomerization of peptide bonds from trans form to cis form at proline residues and facilitates protein folding.

The cyclosporin-cyclophilin A complex inhibits a calcium/ calmodulin-dependent phosphatase, calcineurin, the inhibition of which is thought to suppress organ rejection.

Cyclophilin A is also known to be recruited by the Gag polyprotein during HIV-1 virus infection, and its incorporation into new virus particles is essential for HIV-1 infectivity.

Cyclophilin D is thought to regulate the opening of the matrix of mitochondria pore, because cyclosporin A binds to CyP-D inhibits the pore opening.
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Archaea are dependent upon host Lipids (oil) converting into bad (oxide) cholesterol, only Nician flips it back with Nitric Oxide.

Archaea are also very sensitive to oxygen, and likely manufacture oxides as a result.

i think they put Archaea code into Mycoplasma Laboratorium & Incognitus.

this may go back to the Purple Earth Hypothesis.

the blood clots may be converted lipids & metal waste into amyloid?

they are dumping nano particles on us & forcing vaccines.

chemtrails & biowarfare

Archaea are extremophiles, and according to Garth, thats how modern weaponized microbes began.

thats why i think caramelization of honey & citric acid may be the trick.

it makes a Heterocyclic reduction of antioxidant electrons to Mannose Binding for Lectin dependent microbes.

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![F1.medium.gif](https://images.hive.blog/DQman9XUwx6Za3Mys4C2ZdWbcaLp2wRWThRWNvXE8dmmY7w/F1.medium.gif)

![Screenshot_20221206-225342_Twitter_1.jpg](https://images.hive.blog/DQmYz6rehfHxmp57iYn5DN1feEUWLhEKucM97egDKjceo2v/Screenshot_20221206-225342_Twitter_1.jpg)

Gain of Function

gain of domain x
gain of calcium control

Complex eukaryotic-like actin regulation systems from Asgard archaea

https://www.biorxiv.org/content/10.1101/768580v1.full

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CRISPR GPCR 
G protein-coupled receptors

Genome-Encoded GPCR-Activity Sensors CRISP/Cas9 technology was used to tag GPCRs, including CXCR4, with NLuc or nanoBiT to create various cell-based biosensors

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Hydrogen Sulfide
Calcium Channel

Hydrogen sulfide as a regulator of calcium channels.

A crucial role for hydrogen sulfide in oxygen sensing via modulating large conductance calcium-activated potassium channels.

Hydrogen sulfide (H2S) exerts different effects on the cardiovascular system by modulating ion channels.

Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation

https://pubmed.ncbi.nlm.nih.gov/22570497/

Genomes of two archaeal endosymbionts show convergent adaptations to an intracellular lifestyle

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194110/

Discovery of integrons in Archaea: Platforms for cross-domain gene transfer

https://www.science.org/doi/10.1126/sciadv.abq6376

Archaea: Essential inhabitants of the human digestive microbiota

https://www.sciencedirect.com/science/article/pii/S2452231716300148?via%3Dihu

![106-Biosynthesis-of-Castano.jpg](https://images.hive.blog/DQmNSc6Zk8GwZSxXrEH2qjPkouZ56urwts4RDjFQnsMWR89/106-Biosynthesis-of-Castano.jpg)


The Interplay of Ascorbic Acid with Quinones-Chelators—Influence on Lipid Peroxidation: Insight into Anticancer Activity

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8869476/

Niacin and its metabolites as master regulators of macrophage activation

https://pubmed.ncbi.nlm.nih.gov/27771381/

Natural alkaloid and polyphenol compounds targeting lipid metabolism: Treatment implications in metabolic diseases

https://www.sciencedirect.com/science/article/abs/pii/S0014299920300145?via%3Dihub

Alkaloids Derived from Nicotinic Acid

http://www.epharmacognosy.com/2012/07/alkaloids-derived-from-nicotinic-acid.html?m=1

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Alkaloids are alkaline nitrogenous organic compounds, which widely exist in natural plants. Most alkaloids have complex cyclic structures and exhibit significant activities in lipid metabolism.

Alkaloids are alkaline nitrogenous organic compounds.

Nician flips bad cholesterol into good, Nicotinic Acid an Alkaloid.

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Ribonuclease 
Ribonucleotide

Nucleoside
Nucleotide

Ribo
Ribose

https://www.diffen.com/difference/Nucleoside_vs_Nucleotide

A nucleoside consists of a nitrogenous base covalently attached to a sugar (ribose or deoxyribose) but without the phosphate group. 

A nucleotide consists of a nitrogenous base, a sugar (ribose or deoxyribose) and one to three phosphate groups.

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Glycosylation
Glycan
Glycosyl

Glyphosate
Gly-Phosate
Phosphate

Glycosylation is the reaction in which a carbohydrate (glycan) glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (glycosyl acceptor) in order to form a glycoconjugate.

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all of this is just swapping Phosphate & Nitrogen around?

and Carbon as the Carbohydrate or sugar.

it appears Phosphorus is acting like a wrecking ball?

this goes back to Glyphosate Neutralization, Phosphorus in the wrong formation is Chelating Nucleoside into Nucleotide, damaging misfolding RNA/DNA, likely what cancer is doing, using Phosphorus as a wrecking ball.

it seems that most of the problems are from "Inorganic Phosphate" misfolding DNA?

this next idea is regarding Archaea being more closely related to animals then bacteria.

if Archaea manufacture Carboxysome, does it intermingle with Exosome.

i think Archaea & Mycoplasma coinfection is mislabeled virus?

because why do virus diseases always mutate more lethal & not symbiotic?

i think viruses have an Archaea spawn, using mycoplasma as a vector?

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HEDP phosphate has a certain chelating capacity in addition to corrosion inhibition. The process by which the central ions are combined with two or more coordination atoms with the same multi-tooth ligands is called chelation. The result of chelation is cationic cation (Ca 2+, Mg 2+) and chelating agent interacts to produce stable chelate.

Both dietary and serum levels of inorganic phosphate (Pi) have been linked to development of cancer in experimental studies.

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Phospholipids
Phospho-Lipids

Archon
Archaeon

Phospholipids
Endothelial Cells

Archaeal phospholipids: Structural properties and biosynthesis

https://www.sciencedirect.com/science/article/abs/pii/S1388198116303432?via%3Dihub

THE IMMORTAL, HALOPHILIC SUPERHERO: HALOBACTERIUM SALINARUM – A LONG-LIVED POLY-EXTREMOPHILE

https://microbiologysociety.org/publication/past-issues/real-superheroes/article/the-immortal-halophilic-superhero-i-halobacterium-salinarum-i-a-long-lived-poly-extremophile.html

[The presence of ether-linked phospholipids is a phylogenetic marker that distinguishes Archaea from other life forms.]

Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis

https://www.nature.com/articles/s41418-021-00769-0

Plasticity of ether lipids promotes ferroptosis susceptibility and evasion

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8051864/

Endothelial ether lipids link the vasculature to blood pressure, behavior, and neurodegeneration

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8144742/

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Nanoarchaeota
Nanoarchaeum Equitans
Nanoarchaeum Ignicoccus
Mycoplasma Incognitus

https://en.m.wikipedia.org/wiki/Nanoarchaeota

https://en.m.wikipedia.org/wiki/Nanoarchaeum_equitans

https://en.m.wikipedia.org/wiki/Ignicoccus

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Archaea Carboxysome are being weaponized to interact with our Exosome or Endothelium, manufacturing Ether-Linked Phospholipid Ferroptosis.

this is the true nature of "Gain of Function".

Nanoarchaeota
Nanoarchaeum Equitans
Nanoarchaeum Ignicoccus
Mycoplasma Incognitus

weaponized to hyjack cell nucleus, misfolding proteins.

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Pelagibacterales
SAR11 Clade
HTVC010P

Pelagibacter ubique (an α-proteobacterium of the order Rickettsiales) has the smallest known genome (1,308,759 base pairs) of any free living organism and is one of the smallest self-replicating cells known.

https://en.m.wikipedia.org/wiki/Pelagibacterales

https://en.m.wikipedia.org/wiki/Candidatus_Pelagibacter_communis

https://en.m.wikipedia.org/wiki/HTVC010P

Purple Earth Hypothesis
Haloarchaea
Euryarchaeota
Archaea

Halobacteria are now recognized as archaea rather than bacteria and are one of the largest groups. The name 'halobacteria' was assigned to this group of organisms before the existence of the domain Archaea was realized, and while valid according to taxonomic rules, should be updated.

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Mycoplasma 
Archaea
Apicoplast
Plastid 

Symbiosis or Symbiogenesis?

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Pruning Neuron
GP120

Protein glycosylation in Archaea: Sweet and extreme 

https://academic.oup.com/glycob/article/20/9/1065/1987758?login=false

Bananas
Lichen
H843

https://www.thailandmedical.news/news/breaking-lectins-from-bananas-could-serve-as-an-antiviral-against-the-sars-cov-2-coronavirus-including-emerging-omicron-sub-lineages

Why does COVID-19 cause brain fog? Scientists may finally have an answer.

https://www.nationalgeographic.co.uk/science-and-technology/2022/12/why-does-covid-19-cause-brain-fog-scientists-may-finally-have-an-answer

β4GalT1 Mediates PPARγ N-Glycosylation to Attenuate Microglia Inflammatory Activation

https://pubmed.ncbi.nlm.nih.gov/29717387/

The role of N-glycan modification of TNFR1 in inflammatory microglia activation

https://pubmed.ncbi.nlm.nih.gov/26452604/

Accumulating evidences demonstrated that microglia activation and the autocrine loop of tumor necrosis factor-α (TNFα) greatly contribute to the pathogenesis of several CNS diseases. 

These findings indicated that the N-glycosylation of TNFR1 played an important role during microglia activation in CNS inflammation.

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S1 Domain
Cold-Shock Domain

https://en.m.wikipedia.org/wiki/S1_domain

https://en.m.wikipedia.org/wiki/Cold-shock_domain

The structure of the S1 domain is very similar to that of cold shock proteins. This suggests that they may both be derived from an ancient nucleic acid-binding protein.

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Gain of Function
Integron 
Epithelial Cell α6β4
Cross-Domain 
Horizontal Gene Transfer

Some Archaea found to have integrons, allowing cross-domain gene transfer

https://phys.org/news/2022-11-archaea-integrons-cross-domain-gene.html

https://en.m.wikipedia.org/wiki/Horizontal_gene_transfer

https://en.m.wikipedia.org/wiki/Integrin

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https://en.m.wikipedia.org/wiki/Simian_immunodeficiency_virus

https://en.m.wikipedia.org/wiki/Reverse_transcriptase

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Squid Axoplasm Supports the Retrograde Axonal Transport of Herpes Simplex Virus.

https://www.thefreelibrary.com/Squid+Axoplasm+Supports+the+Retrograde+Axonal+Transport+of+Herpes...-a057815562

Genomes of two archaeal endosymbionts show convergent adaptations to an intracellular lifestyle

https://www.nature.com/articles/s41396-018-0207-9

Cetirizine is a carboxylic acid metabolite of hydroxyzine with the carboxyl group having a negative charge at physiologic pH. 

Cetirizine is highly specific for the H1 receptor inhibitor.

https://alivenhealthy.com/2021/09/30/suramin-and-pine-needle-essential-oil-covid-treatment-long-haul-covid-treatment-and-post-covid-vaccine-treatment/

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Sub-Cellular Identification of Functional Amyloids in Bacteria and Archaea by Infrared Nanospectroscopy

https://pubmed.ncbi.nlm.nih.gov/34927901/

Amyloid found in many different bacterial species and has have also been discovered in Archaea. 

For example, individual cells of the methanogen Methanosaeta, which is a strict anaerobe, are encased in an extracellular cell wall sheath composed mainly of the major sheath protein (MspA), which adopts an amyloid fold.

We confirm the highly amyloidogenic nature of the cell wall sheaths of the archaea Methanosaeta, which effectively acts as an “amyloid cocoon.”

however GWS CVBS operates, will likely be how all chronic disease operates, an possibly Endothelium Cells is an important clue, regarding if its a parasite, and the size of it.

i really do think bacteria or archaea are literally manufacturing viruses to communicate data & combating other microbes, and occasionally become pathogenic in the crossfire.

can we match the largest ocean Pandora viruses up with an unusually large microbe? like a puzzle game, match the critter.

for example, archaea living in boiling acid hot spring, and they are riddled with unclassified viruses, but arnt viruses normally sensitive to boiling acid?

Gain of Function is identical to the manufacturing Mycoplasma Incognitus, taking extremophile parts, mixing with pathogens & made to act as bacteriophage  jumping between bacteria & endothelial cells, mitochondria, and going dormant in bones & brain.

manufacturing a toxic environment inside of us, and being shielded inside other microbes, mycoplasma, amyloid or carboxysome shells, until they find the right spot to hide & grow.

Professor Garth Nicolson explained how to make Gulf War Syndrome, they took extremophiles parts from sea vents & put them into Mycoplasma Incognitus, my point is the definition of Archaea is Extremophile, they manufacture Amyloid & are dependent upon external sources of Lipid, literally converting our oil into Amyloid.

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beginning to suspect that viruses are carboxysome manufactured by archaea & bacteria for both communication & biological warfare, and us caught in the crossfire.

because in a laboratory isolation, archaea & bacteria are riddled with viruses.

the only way to isolate a virus is by killing archaea & bacteria.

possibility leaving only carboxysome  to convert into a virus, without the bacteria host, the data enters mitochondria nucleus as endosymbiont.

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https://en.m.wikipedia.org/wiki/Benzhydryl_compounds

https://en.m.wikipedia.org/wiki/Cetirizine

https://en.m.wikipedia.org/wiki/Diphenylmethylpiperazine

https://en.m.wikipedia.org/wiki/Phenoxyethanol

https://en.m.wikipedia.org/wiki/Hydroxyzine

Heterocyclic Systems 

Quinazoline is a biologically imperative scaffold known to be linked with several pharmacological activities. Some of the protuberant pharmacological responses attributed to this system are analgesic, anti-inflammatory, anti-convulsant, sedative-hypnotic, anti-histaminic, anti-hypertensive, anti-cancer, anti-microbial, anti-tubercular and anti-viral activities. 

Cetirizine contains L- and D-stereoisomers. Chemically, levocetirizine is the active L-enantiomer of cetirizine. The drug is a member of the diphenylmethylpiperazine group of antihistamines. 

Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group replaced by a nitrogen atom.

this is what i think is going on..

Pyridine Heterocyclic
Benzene Polyphenol

its very small molecules, that can detox very small toxins, and bind to nanobacteria size critters.

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Butyrate: fiber fermentation

Butyrate's effects on the immune system are mediated through the inhibition of class I histone deacetylases and activation of its G-protein coupled receptor.

Nician
Butyric acid

https://en.m.wikipedia.org/wiki/Hydroxycarboxylic_acid_receptor_2

https://en.m.wikipedia.org/wiki/Butyric_acid

The Phospholipid Profile of Mycoplasmas

https://www.hindawi.com/journals/jl/2012/640762/

Cholesterol and phospholipid uptake by mycoplasmas

Kinetics of cholesterol and phospholipid exchange between mycoplasma membranes and lipid vesicles

https://en.m.wikipedia.org/wiki/Glycerophospholipid

The metabolism of glycerophospholipids is different in eukaryotes, tumor cells, and prokaryotes.

Two major classes are known: those for bacteria and eukaryotes and a separate family for archaea.

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Breaking: SARS-CoV-2 Spike found in bacteria samples taken from China, 2019

https://adeno-news.com/2023/01/20/breaking-sars-cov-2-spike-found-in-bacteria-samples-taken-from-china-2019/

Unique SARS-CoV-2 genomes found in Antarctic samples raises questions about SARS-CoV-2 origin, lineages

https://adeno-news.com/2022/08/09/unique-sars-cov-2-genomes-found-in-antarctic-samples-raises-questions-about-sars-cov-2-origin-lineages/

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A group of Hungarian scientists have recently reported the discovery of SARS-CoV-2 sequences within a set of antarctic soil samples taken in a 3-week-period after 24-12-2018, submitted by the University of Science and Technology of China under the BioProject accession PRJNA692319.

According to the author of PRJNA692319, the DNA from these samples were extracted in December 2019 and sent to Sangon Biotech, Shanghai, China for sequencing.

PRJNA692319 may plausibly represent a cell cultured isolate of SARS-CoV-2 that is already present within a Chinese laboratory before the start of the COVID-19 pandemic.

SARS-CoV-2 genomic sequences corresponding to both A,B lineage as well as USA-WA-1 was found within samples of Antarctic soil that were extracted and sent for sequencing in December 2019, 101 runs prior to the first sequencing of samples taken from “viral pneumonia of unknown etiology” patients from the Huanan seafood market by the Wuhan Institute of Virology.

SARS-CoV-2 Spike protein is present within Bacterial whole-genome sequencing assembly data, deposited under PRJNA839565, that supposedly contained sequences taken from isolated samples of Pseudomonas Aeruginosa that were taken from patients in 2019, Henan.

More specifically, the SARS-CoV-2 Spike protein have been found within the following 4 WGS shotgun contig sequences, each corresponding to a cultured isolate derived from a Pseudomonas Aeruginosa.

As the cells found within the contaminated antarctic soil samples also show evidence of cell-to-cell fusion and mitochondrial DNA chimerism, a connection between these plasmid-borne, fusion-competent Spike protein sequences and the unique cell type found within these samples also can not be ruled out.

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Pseudomonas Aeruginosa
Gammaproteobacteria

https://en.m.wikipedia.org/wiki/Pseudomonas_aeruginosa

Pseudomonas aeruginosa is also able to decompose hydrocarbons and has been used to break down tarballs and oil from oil spills.

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are Gammaproteobacteria or even Nanobe even bacteria, is why they just changed the classification, probably archaea.

Ascorbic Acid
Bromelain

Biochemical role of vitamin C is to act as an antioxidant (reducing agent) by donating electrons to various enzymatic and non-enzymatic reactions. Doing so converts vitamin C to an oxidized state, either as semide-hydroascorbic acid or dehydroascorbic acid. These compounds can be restored to a reduced state by glutathione and NADPH-dependent enzymatic mechanisms.

In plants, vitamin C is a substrate for ascorbate peroxidase. This enzyme utilizes ascorbate to neutralize excess hydrogen peroxide (H2O2) by converting it to water (H2O) and oxygen.