New life at the boundary of academia and the real world. by scienceblocks

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hive-196387 · @scienceblocks · May 12 '22

$9.61

New life at the boundary of academia and the real world.

![academia-1293362_960_720.png](https://files.peakd.com/file/peakd-hive/scienceblocks/48FDvh6RQGLM2bdEDi2wLwE6LS4m59o5XaHe3AnpjYreP9uFL1G49LiTmqsQ4o7kbv.png)

**At the end of my journey in academia**
*Source: [Pixabay](https://pixabay.com/vectors/academia-academic-board-business-1293362/)*

2 months ago I was about to make another post with Veeru and then came in 2 emails. One was about asking me to submit my PhD thesis (Phew! finally). But the second one was even more interesting. It was about being awarded a grant for taking forward the research I am my colleague have been doing on antiviral drugs. And bam!

Saying that life has been hectic, would be an understatement today. It's 2 am at night and I am wide awake, writing thesis and feeling overwhelmed. Last I had time to breathe and sleep, there was a nuclear threat looming over the world. And somewhere at back of my head I thought that I need to finish my PhD before the nuclear winter.

Anyhow, what was I saying? Why am I here writing random stuff instead of my thesis at 2 am? I just felt like putting words to my thoughts. My brain is in such a split right now. After spending 9+ years in academia the business world seems completely alien.

### How to sell your science? The challenges

A part of my the project would need me to conduct experiments, design animal trials, analyze data and write about it. I love this part. This is what I do. This is what I am familiar with.

But, then comes the challenging part. What is the market for the end product that would result from my work? Why would anyone buy it? Is the method of drug synthesis and production scalable to large scale? Will it work outside the 4 walls of the lab - that is if it will pass the clinical tests for safety and efficacy?

Then comes the challenge of interacting with people who are expert in business. You see, as grad student you become an expert in your domain (which only a rare few people on the planet ever cared about anyway). You know so much about that one tree in the forest, and sometimes nothing at all about the forest. And now you present you research to people who may or may not be of your domain. But they sure as hell know - "what sells". And all of sudden from being the alpha in the room, who can see data in so many dimensions, you realize - "Wait a minute, where was this dimension of real world all this while?"

### The translation - the lab bench to real world

![test-g1090015f0_640.jpg](https://files.peakd.com/file/peakd-hive/scienceblocks/Ep3dogexLvowZwkRiYJ2D8giFn6yJjTQwRDW6P2uWGF84fjBf9hriebCqw3fvviGMUp.jpg)

</div>

![783px-Bioreaktor_quer2.jpg](https://files.peakd.com/file/peakd-hive/scienceblocks/23xVPTs15dRQYiode11Sj4d6xk8FGAbzpUkGUnNS9NTgyZomCDr18QowzdDord75WN4aw.jpg)
</div>

**Scaling up: From the test tube to the The Bioreactor**
*Source: [Test tube from pixabay](https://pixabay.com/photos/test-tube-lab-medical-research-214185/) and [Bioreactor](https://commons.wikimedia.org/wiki/File:Bioreaktor_quer2.jpg) by Eva Decker*

Anyhow, I will be signing the contract in a few weeks and in the first time, since forever, I will be stepping into the zone where science impacts the real world. Well to be fair I am still far away from that zone. It is more bridge between the basic science we do in the labs and the market which eventually puts that science science to use. From how I see there are layers of succession to reach that point. In fact I recently found out that they actually have names for these layers. They are called the [technology readiness levels (TRLs)](https://euraxess.ec.europa.eu/career-development/researchers/manual-scientific-entrepreneurship/major-steps/trl).

In a nutshell, TRLs a concept first introduced by NASA is used define the maturity of a given technology. TRL 1 is basically when you have eureka moment and you read and figure out if your idea is even feasible. TRL 2 is when you have preliminary data. TRL 3 is when you have shown proof of concept at a basic level. If you were working with drugs TRL 3 would be when you have shown that your drug can inhibit the disease in isolated cells and animal models in a small scale. So TRL 3 is where you see the bridge in front of you. TRL 4 is where the game begins.

Until TRL 3 it was all at lab scale. TRL 4 needs you to perform large scale pre clinical studies and demonstrate safety and efficacy. The further TRL deals with clinical trials, regulatory clearances and market entry. We have reached to TRL 3 easily. And now it is time to take up big challenges.

I honestly don't know if I will succeed or fail. I think it is going to be another adventure in life. And I would be writing about how it goes. If it succeeds or if it fails. And more importantly the factors that would lead to success or failure. So let the game begin.

Anyhow, this is not the kind of science posts I write. This is more like something I wanted to share about my experience shifting zones from basic science to applied science. Science, nonetheless. Anyway I have lot on mind to talk about. However, for now I will get back to my thesis.

Signing off
@scienceblocks

# References
[ABOUT TECHNOLOGY READINESS LEVELS](https://euraxess.ec.europa.eu/career-development/researchers/manual-scientific-entrepreneurship/major-steps/trl)

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properties (23)vote details (381)

voter	rshares	pct
kevinwong	1,635,558,397	0.21%
justtryme90	685,850,782	35%
eric-boucher	6,644,257,743	1.4%
juanmiguelsalas	581,612,682	0.84%
thecryptodrive	15,806,396,285	0.56%
kaylinart	618,662,706	1.4%
mammasitta	3,680,007,191	1.4%
roelandp	609,677,433,375	17.5%
onthewayout	12,027,537,244	100%
cloh76	1,976,371,349	1.4%
akipponn	1,656,841,221	17.5%
stephen.king989	658,186,011	1.4%
djennyfloro	523,964,078	10%
rmach	1,197,264,370	17.5%
lemouth	809,068,854,210	35%
lamouthe	2,680,573,298	35%
eftnow	557,025,312	1.4%
tfeldman	2,629,900,414	1.4%
metabs	3,369,842,138	35%
mcsvi	135,728,576,325	50%
lk666	773,641,141	1.4%
cnfund	5,050,016,865	2.8%
justyy	12,845,921,840	2.8%
michelle.gent	1,501,700,505	0.56%
curie	303,215,111,298	2.8%
modernzorker	1,655,722,908	1.96%
techslut	85,072,518,498	14%
slider2990	2,151,779,227	15%
roguewriter	1,738,194,314	17.5%
steemstem	2,075,608,554,557	35%
yadamaniart	1,139,747,047	1.4%
apsu	750,998,110	0.98%
walterjay	200,987,918,980	17.5%
valth	5,414,263,684	17.5%
driptorchpress	739,083,801	0.7%
gabriele-gio	3,008,374,645	1.4%
sardrt	1,237,057,024	10%
dna-replication	1,345,550,998	35%
ambyr00	1,641,791,768	0.42%
dhimmel	139,395,849,384	8.75%
oluwatobiloba	1,095,181,355	35%
detlev	7,764,345,720	0.84%
federacion45	3,750,309,338	1.4%
mobbs	62,500,218,143	17.5%
jerrybanfield	11,075,150,527	2.8%
roomservice	1,409,294,275	1.4%
rt395	1,199,778,295	1.5%
bitrocker2020	4,314,193,456	0.42%
newsflash	600,117,579,681	0.98%
sustainablyyours	1,489,924,791	1.4%
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yehey	5,289,814,162	2.8%
helo	2,434,770,681	17.5%
samminator	9,394,272,875	3.5%
mahdiyari	1,043,165,922,075	80%
lorenzor	1,345,430,814	50%
firstamendment	62,573,747,452	50%
sam99	16,118,453,761	21%
amimohan	4,719,951,177	100%
alexander.alexis	21,458,393,542	35%
jayna	2,736,413,553	0.56%
ew-and-patterns	8,113,696,570	3%
deanlogic	654,312,121	1.4%
hhayweaver	509,274,242	0.7%
princessmewmew	3,778,263,410	1.4%
gunthertopp	29,500,346,591	0.58%
pipiczech	1,023,205,552	2.8%
binkyprod	1,478,316,587	1.4%
ludmila.kyriakou	4,706,297,751	10.5%
flatman	2,344,391,486	2.8%
samest	7,650,555,147	50%
analealsuarez	701,971,952	50%
minnowbooster	1,207,638,859,101	20%
howo	1,065,459,388,831	35%
tsoldovieri	3,617,698,116	17.5%
neumannsalva	1,918,712,833	1.4%
stayoutoftherz	53,676,708,773	0.7%
abigail-dantes	12,936,026,142	35%
coindevil	1,310,790,810	2.24%
zonguin	1,615,410,858	8.75%
sciencevienna	0	100%
investingpennies	7,475,022,535	2.8%
francosteemvotes	1,402,809,381	10.5%
martibis	815,638,925	0.56%
val.halla	2,869,753,262	10%
mochita	0	100%
travelingmercies	605,234,629	2.8%
redrica	917,523,247	1.4%
iamphysical	13,628,688,709	90%
dipom98	559,856,560	1.4%
aaronleang	4,996,634,442	25%
zyx066	3,257,982,114	1.4%
revo	2,469,018,558	2.8%
azulear	1,954,650,616	100%
djlethalskillz	852,980,574	5%
psicoluigi	857,975,835	50%
thelordsharvest	2,814,202,849	2.8%
massivevibration	20,522,127,234	30%
evildido	576,453,947	5.25%
bradfordtennyson	538,163,045	1.4%
trevorpetrie	1,247,708,979	1.4%
aidefr	2,080,183,843	7.87%
torico	688,168,339	0.92%
sorin.cristescu	3,971,043,108	1.4%
inthenow	15,701,301,457	25%
majes.tytyty	515,359,055	10%
cryptononymous	896,334,438	1.4%
upme	827,508,930	1.4%
dauerossi	5,407,747,209	30%
meno	9,905,010,131	1.4%
fatkat	707,864,580	1.39%
bhoa	3,155,311,533	17.5%
enzor	1,019,054,900	17.5%
bartosz546	1,490,232,717	1.4%
carloserp-2000	5,018,857,304	100%
sunsea	1,610,607,842	1.4%
postpromoter	1,128,479,521,820	35%
bluefinstudios	1,489,965,719	0.84%
steveconnor	1,873,818,198	1.4%
sankysanket18	754,647,846	17.5%
dbddv01	1,040,248,534	8.75%
paulmoon410	1,470,030,625	15%
johnspalding	678,593,796	1.4%
nicole-st	2,602,840,012	1.4%
travoved	1,760,928,425	50%
aboutcoolscience	5,327,794,638	35%
kenadis	9,464,524,641	35%
lpv	638,358,108	1.96%
punchline	6,420,640,510	2.8%
sneakyninja	5,811,814,198	9.18%
gentleshaid	21,480,241,212	100%
sco	9,526,713,134	35%
anikekirsten	1,834,416,708	17.5%
ennyta	985,572,650	50%
juecoree	18,977,937,264	21%
stahlberg	615,499,487	1.4%
gabrielatravels	571,578,035	0.98%
carn	726,667,056	2.52%
branbello	739,875,300	6.46%
intrepidphotos	953,572,966,063	26.25%
fineartnow	1,821,755,126	1.4%
hijosdelhombre	45,177,220,207	40%
mathowl	64,093,036,523	100%
yoghurt	977,191,173	2.8%
steemvault	967,209,913	2.8%
steem4all	570,460,497	1.4%
communitybank	3,490,464,258	2.8%
fragmentarion	8,679,776,691	35%
hadji	666,251,781	100%
utube	2,161,307,770	2.8%
jigstrike	865,664,997	1.4%
asgharali	874,155,671	1.4%
m1alsan	559,555,109	1.4%
neneandy	3,190,071,452	2.8%
sportscontest	2,649,718,973	2.8%
videosteemit	1,009,873,610	2.8%
stemng	25,354,269,589	100%
kingabesh	2,023,086,914	50%
miguelangel2801	790,030,624	50%
mproxima	834,098,798	1.4%
fantasycrypto	1,022,138,474	1.4%
didic	937,885,204	1.4%
mastergerund	5,602,623,004	18.37%
emiliomoron	145,980,385,051	50%
dexterdev	1,412,233,524	17.5%
photohunt	1,739,357,856	2.8%
geopolis	2,314,467,118	35%
robertbira	3,766,728,520	8.75%
the.chiomz	1,108,952,060	55%
alexdory	5,610,922,976	35%
irgendwo	5,208,145,256	2.8%
aotearoa	1,282,323,491	2.8%
flugschwein	1,801,674,510	29.75%
charitybot	4,723,099,012	100%
cyprianj	13,106,173,537	50%
kieranstone	540,132,284	0.92%
citimillz	695,755,154	1.4%
francostem	4,846,912,833	35%
endopediatria	694,262,746	20%
technologix	1,696,491,342	2.8%
croctopus	1,541,119,735	100%
zipporah	1,352,048,116	0.56%
superlotto	8,746,489,299	2.8%
djoi	2,001,388,072	50%
positiveninja	502,195,179	1.4%
proto26	1,041,524,079	2.8%
scottcbusiness	467,948,358	1.4%
tomastonyperez	16,980,013,436	50%
bil.prag	935,292,665	0.14%
elvigia	11,124,669,062	50%
sanderjansenart	2,387,063,381	1.4%
vittoriozuccala	985,131,633	1.4%
qberry	1,723,459,287	1.4%
sbi2	1,336,906,763,886	64.19%
rambutan.art	526,905,903	2.8%
gadrian	94,761,041,320	26.25%
therising	49,862,209,978	2.8%
cryptocoinkb	1,012,351,812	1.4%
gifty-e	763,055,763	80%
scruffy23	20,024,817,160	50%
de-stem	19,286,965,255	34.65%
serylt	1,591,629,142	34.3%
gogreenbuddy	1,631,533,411	2.8%
josedelacruz	4,366,279,668	50%
achimmertens	5,980,564,346	1.4%
lorenzopistolesi	3,362,546,251	1.4%
kgakakillerg	15,194,580,730	10%
charitymemes	523,932,404	100%
realblockchain	14,160,695,801	50%
erickyoussif	814,606,230	100%
meanbees	21,032,503,882	10%
indigoocean	597,676,875	1.4%
primersion	220,454,880,534	20%
deholt	2,007,320,987	29.75%
diabonua	2,356,096,303	1.4%
pladozero	31,768,053,252	10%
nateaguila	179,003,945,218	5%
stevenwood	1,365,275,086	0.93%
enforcer48	123,177,768,880	15%
temitayo-pelumi	4,268,354,051	50%
andrick	858,970,651	50%
yusvelasquez	93,821,264,295	50%
motherofalegend	5,138,213,145	17.5%
doctor-cog-diss	27,923,048,317	35%
trisolaran	761,478,976	1.4%
realkiki85	4,630,034,358	100%
marcuz	958,249,656	17.5%
cooltivar	1,453,601,666	0.56%
acont	34,814,482,116	50%
uche-nna	3,060,168,755	2.24%
anaestrada12	1,921,166,340	100%
citizendog	2,072,688,670	2.8%
cheese4ead	1,841,177,329	1.4%
jd4e	3,600,073,540	50%
blewitt	818,908,150	0.16%
drsensor	755,362,983	28%
thedailysneak	7,821,885,274	9.18%
bflanagin	3,178,749,730	1.4%
armandosodano	6,969,398,745	1.4%
goblinknackers	55,188,859,687	7%
zuerich	537,699,421,446	10%
reinaseq	6,731,090,563	100%
vixmemon	710,673,287	2.1%
yaelg	538,048,505	0.84%
kylealex	4,723,157,185	10%
minnowspeed	3,953,167,064	50%
orlandogonzalez	3,453,782,151	25%
cleanplanet	7,634,560,629	0.84%
fran.frey	4,180,065,381	50%
perpetuum-lynx	1,049,370,886	34.3%
pboulet	40,861,249,849	28%
josesalazar200	1,043,050,379	2.8%
stem-espanol	43,713,787,385	100%
babysavage	2,746,141,772	18.37%
ravensavage	2,275,043,030	18.37%
cliffagreen	1,042,590,329	10%
aleestra	12,033,764,300	80%
the.success.club	1,189,925,275	1.4%
meanroosterfarm	674,929,260	17.5%
teemike	815,551,251	50%
brianoflondon	9,198,597,525	0.42%
giulyfarci52	1,708,642,031	50%
esthersanchez	4,091,551,047	60%
steemcryptosicko	5,853,363,780	0.56%
cowpatty	700,742,756	17.5%
stem.witness	2,043,596,639	35%
devann	1,040,945,613	0.28%
mechanicalowl	649,417,831	50%
regularowl	1,153,425,380	50%
wilmer14molina	2,004,224,860	100%
bit4bit	3,839,780,745	2.8%
vaultec	6,397,369,134	12%
steemstorage	3,162,031,791	2.8%
starfighter	604,906,804	2.8%
aqua.nano	600,524,909	17.5%
jtm.support	2,710,812,375	35%
crowdwitness	8,471,249,013	17.5%
eternalsuccess	17,127,449,293	17.5%
hairgistix	1,489,972,726	1.4%
steemean	10,050,938,500	5%
filosof103	644,633,613	1.4%
photographercr	1,154,640,064	0.56%
memehub	1,269,368,262	1.4%
epicdice	1,948,714,424	0.84%
iamsaray	774,187,656	1.4%
monsterjamgold	4,550,366,813	10%
deeanndmathews	895,496,300	1.4%
robibasa	23,322,041,529	10%
beerlover	920,007,209	0.84%
tggr	571,475,942	1.4%
aicu	16,365,726,187	2.8%
walterprofe	1,894,666,571	17.5%
zeruxanime	2,195,728,320	17.5%
afarina46	950,217,625	17.5%
mind.force	686,568,156	0.7%
kgswallet	1,044,846,987	20%
stemgeeks	9,597,685,259	30%
stemcuration	592,572,278	30%
babytarazkp	3,518,498,840	40%
tokensink	1,404,893,729	2.8%
sbi-tokens	6,217,296,087	18.37%
nazer	1,227,258,064	17.5%
rosana6	651,264,267	1.4%
shtup	474,936,155	0.56%
andylein	83,182,524,521	80%
steemstem-trig	2,857,277,885	35%
sandymeyer	8,668,194,623	0.35%
yggdrasil.laguna	141,784,085	15%
atheistrepublic	2,829,375,683	1.4%
ibt-survival	33,535,546,723	10%
delilhavores	728,067,881	3.5%
hjmarseille	1,275,217,472	24.5%
abachon	908,881,723	2.8%
zirky	10,620,436,716	25%
mengene	458,232,468	17.5%
peterale	5,024,909,385	1.4%
hive-127039	501,197,336	25%
dpend.active	643,847,343	1.83%
stuntman.mike	8,684,216,264	100%
hivequebec	654,837,989	10.5%
laruche	394,934,120,554	10.5%
ykretz	2,260,376,454	5%
stemsocial	218,475,565,214	35%
kyleana	559,773,750	17.5%
holoferncro	17,419,134,985	10%
sketching	991,654,463	9.18%
hiveonboard	694,512,078	1.4%
taniagonzalez	607,358,616	10%
schmidi	819,830,197	1.26%
quinnertronics	6,021,053,051	3%
sevenoh-fiveoh	1,059,059,787	5%
treefiddybruh	600,415,095	1.4%
aabcent	5,143,477,344	2.24%
altleft	8,395,963,708	0.02%
chubb149	1,129,386,028	4.2%
acungametrailers	499,272,369	100%
cosplay.hadr	536,570,223	2.8%
hadrgames	554,196,726	2.8%
bubblegif	896,983,090	1.4%
brofund-stem	526,646,281	15%
labeba1969	620,950,946	1.4%
meritocracy	30,966,286,307	0.28%
stemline	1,887,062,529	15%
sillybilly	519,123,347	100%
mundo.curioso	195,033,787	100%
adamada.stem	2,193,300,924	100%
arunbiju969	1,175,198,137	14%
nanggroe1	1,759,251,702	40%
drricksanchez	6,369,234,936	1.4%
miroslaviv	854,146,201	1.4%
maxelitereturned	797,066,001	17.5%
krrizjos18	1,576,114,993	17.5%
holovision.stem	84,861,433	50%
dibblers.dabs	533,046,320	0.47%
jessicaossom	1,948,278,392	1.4%
pinkfloyd878	4,352,787,467	100%
star.stem	1,559,891,713	50%
solominer.stem	788,230,914	100%
mayberlys	2,049,835,340	50%
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@alexanderalexis · May 15 '22

$0.04

I remember Eminem mentioning TRL is his White America song. It probably referred to a drug testing stage :D

👍 alexander.alexis, scienceblocks

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@scienceblocks · May 17 '22

Haha probably. I just checked out the song. 😁

👍 alexanderalexis

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@gentleshaid · May 14 '22

First of all, lemme congratulate you, even though you mentioned it already via discord. We all know that there are no right or wrong answers to research as long as the methodology is correct. Hence, your concerns, even though valid, are just mere anxieties. What is the worst that can happen if, let's say, your drug refuses to pass the clinical tests for safety and efficacy? A ground for more research, I guess. In other words, it's not likely you will be a failure. That is why we don't just accept alternate hypotheses in science. 

When it comes to selling, that should not be your business, you are a scientist, not a businessman.

I wish you the best in your future endeavours.

👍 scienceblocks

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@scienceblocks · May 15 '22

Thanks for those encouraging words. 🙂

👍 gangstalking

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@hivebuzz · May 25 '22

Congratulations @scienceblocks! You received a personal badge!

<table><tr><td>https://images.hive.blog/70x70/http://hivebuzz.me/badges/birthday-4.png</td><td>Happy Hive Birthday! You are on the Hive blockchain for 4 years!</td></tr></table>

<sub>_You can view your badges on [your board](https://hivebuzz.me/@scienceblocks) and compare yourself to others in the [Ranking](https://hivebuzz.me/ranking)_</sub>


###### Support the HiveBuzz project. [Vote](https://hivesigner.com/sign/update_proposal_votes?proposal_ids=%5B%22199%22%5D&approve=true) for [our proposal](https://peakd.com/me/proposals/199)!

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@lemouth · May 17 '22

Hey scienceblocks! It is nice to read from you again. Apologies for the delayed answer. I am less present during week-end time. You know, family and related matters... But here I am, finally, four days later!

It is interesting to read how you have evolved (or will soon be, more precisely). As a side note, I have always been curious on what is going on in the real world, which is something I don't really care with my field (I guess we can say that what I do is TLR -10 :D ).  I therefore wish you good luck and hope you will have as much fun as with you PhD (congrats for the upcoming submission).

I hope to still read science blogs from you once in a while (I can imagine that what you will do next will be under some NDAs).

Cheers!

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@scienceblocks · May 17 '22

$0.07

Totally get the weekend thing. I won't say particle physics is at TRL -10. I remeber in my college days, in a viva voice exam the external asked me to explain NMR. And I started from Spin of quarks and then took him to hydrogen atoms and structure of molecules. Now after 10 years NMR comes ro haunt me again, in a good way. It is a key tool for drug development. And many such tools have resulted from our understanding of the atoms. PET is another example. And who knows what else cool things we will see in future based on what you are publishing after smashing those atoms. 
And yes, I will keep writing. In fact I was telling my friend the other day that I enjoy writing more than what I opted to pursue. So that is gonna stay. I also have to an itch to write about my thesis work. I guess one more week, till I submit, after that I will make a layman summary of it.

👍 lemouth

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@lemouth · May 17 '22

Okay. Please let me rephrase: "<i>theoretical particle physics</i>". 

Building a better theory explaining how our universe works won't give any application short-term-wise. However, we train people, we provide them skills to solve hard problems, and innovation comes from the conception of our experiments (to limit myself to few examples). Therefore, there is an added value to the society. I would just not classify it in terms of TRL.

> And yes, I will keep writing. In fact I was telling my friend the other day that I enjoy writing more than what I opted to pursue. So that is gonna stay. I also have to an itch to write about my thesis work. I guess one more week, till I submit, after that I will make a layman summary of it.

I am looking forward to read this! You can count on my comments and questions :)

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@stemsocial · May 14 '22

re-scienceblocks-new-life-at-the-boundary-of-academia-and-the-real-world-20220514t203334071z

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