The future is leper! by trumpman

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hive-163521 · @trumpman · Nov 18 '22

$17.85

The future is leper!

I was checking some science news this morning and stumbled upon a really interesting and bizarre paper in the field of tissue regeneration.

My guess is you have probably heard of leprosy, a disease that is pretty much"forgotten" in the western world. If you haven't, Wikipedia has a great article on it https://en.m.wikipedia.org/wiki/Leprosy , feel free to check it out.

Anyways, in this new paper researchers have discovered that Mycobacterium leprae (the bacterium responsible for the disease) promotes the regrowth of liver tissue. Of course this isn't a selfless act, it's for the bacterium to have more tissue to infect 😅 But what's really interesting is that the regrown tissue is not defective or cancerous but totally healthy and functional.

Don't get your hopes super up though, as this research was done on armadillos. And armadillos aren't... human so the microorganism may exhibit a totally different behavior on us. Still, an interesting and promising research!

Below follows a photo from the study and the abstract

![fx1.jpg](https://files.peakd.com/file/peakd-hive/trumpman/AK9T8aL8pMsMAFdhdxKhikgJcA1N1NGy4HyJBE6UiFxLk4SVfZTgExU1Ycn7QjQ.jpg)

> Summary
Ideal therapies for regenerative medicine or healthy aging require healthy organ growth and rejuvenation, but no organ-level approach is currently available. Using Mycobacterium leprae (ML) with natural partial cellular reprogramming capacity and its animal host nine-banded armadillos, we present an evolutionarily refined model of adult liver growth and regeneration. In infected armadillos, ML reprogram the entire liver and significantly increase total liver/body weight ratio by increasing healthy liver lobules, including hepatocyte proliferation and proportionate expansion of vasculature, and biliary systems. ML-infected livers are microarchitecturally and functionally normal without damage, fibrosis, or tumorigenesis. Bacteria-induced reprogramming reactivates liver progenitor/developmental/fetal genes and upregulates growth-, metabolism-, and anti-aging-associated markers with minimal change in senescence and tumorigenic genes, suggesting bacterial hijacking of homeostatic, regeneration pathways to promote de novo organogenesis. This may facilitate the unraveling of endogenous pathways that effectively and safely re-engage liver organ growth, with broad therapeutic implications including organ regeneration and rejuvenation.

Link to paper - > https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(22)00379-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2666379122003792%3Fshowall%3Dtrue

And here's a dumbed down article about the study from BBC along with some remarks from the authors -> https://www.bbc.com/news/health-63626239

Have fun reading!

Posted with [STEMGeeks](https://stemgeeks.net)

👍 brofi, steemychicken1, trumpman, ezrider, mahdiyari, minnowbooster, lordbutterfly, arcange, josediccus, jim888, maarnio, pdq, nfttunz, steemstem, utopis, agmoore, neal.power, d-company, ruth-girl, cryptoandcoffee, dalz, steemflagrewards, howo, postpromoter, dhedge, lemouth, penguinpablo, gubbatv, cryptomaniacsgr, enforcer48, epic-fail, urtrailer, solairitas, marcocasario, intrepidphotos, logic, hatoto, johannpiber, onealfa.leo, steliosfan, roleerob, mcsvi, bluerobo, jlsplatts, rocky1, aaronkroeblinger, dandays, htooms, pixresteemer, scooter77, curie, memehub, venarisyndicate, stemsocial, fieryfootprints, firstamendment, onepercentbetter, alexvan, digital-fortress, nbs.gmbh, urun, splatts, dhimmel, filotasriza3, and 366 others

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pinkfloyd878	4,427,259,851	100%
star.stem	1,671,597,418	50%
solominer.stem	862,669,745	100%
solominer.leo	766,289,043	100%
ayee11	903,835,381	100%
astil.radix	9,699,378	100%
olympicdragon	2,272,681,657	100%
danokoroafor	12,903,318,291	100%
aries90	6,159,066,068	0.8%
migka	4,295,797,379	90%
trasto	2,810,220,846	25%
gejzep	10,013,670,806	5%
uno.alfa	1,681,420,709	100%
beffeater	2,950,554,839	50%
saboin.stem	108,082,211	20%
thgaming	1,427,713,594	12.5%
hoosie	6,517,641,084	100%
hivefolks	23,175,266,642	100%
gwajnberg	2,270,317,003	40%
pob-curator	0	80%
neoxag-curator	0	80%
stem-curator	0	100%
vyb-curator	0	80%
dondido	3,333,859,704	0.8%
venarisyndicate	87,571,586,619	100%
prosocialise	13,463,216,546	5%
jacr	0	100%
jamourhihi	0	100%
olujay	19,053,061,357	70%
pimp-curator	130,332,349	100%
anomadsoul.vyb	2,121,580,123	100%
buezor	1,483,401,227	80%
kryptofire	719,082,821	15%
med-hive	499,491,410	5%
cent-booster	1,683,749,051	100%
gubbahomestead	24,256,628,891	100%
minas-glory	744,193,562	0.4%
trumpybear	16,742,842,001	100%
neal.power	496,998,146,984	100%
the-grandmaster	639,036,083	0.4%
the-burn	818,690,783	0.4%
fun-curator	130,417,546	100%
ambicrypto	2,215,558,546	0.8%
superuser3	1,982,236,026	5%
truth2.stem	1,797,353,442	100%

@agmoore · Nov 19 '22

$1.25

Every now and then you come up with a fascinating article 😄.   Armadillos in the U.S. are [vectors of the disease.](https://www.healio.com/news/infectious-disease/20160615/armadillos-vectors-of-leprosy-in-the-us) More than one hunter who killed an armadillo for dinner came down with leprosy. Maybe the animal's ability to grow livers is related to why they catch the disease and how they spread it to humans.  We still don't clearly understand how leprosy [is transmitted.](https://www.cdc.gov/leprosy/transmission/index.html) The liver thing might offer a clue.


Just a thought :)

👍 steemychicken1, trumpman, ruth-girl, giotists, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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properties (23)vote details (8)

voter	rshares	pct
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@trumpman · Nov 19 '22

$0.23

People eat armadillos? Oh geez

👍 agmoore, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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@agmoore · Nov 19 '22

😂

👍 stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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@cmmemes · Nov 18 '22

$0.12

looking for a way to regrow that alcohol damaged liver ? :))

👍 steemychicken1, trumpman, ruth-girl, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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voter	rshares	pct
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@trumpman · Nov 19 '22

🤫🤫🤫🤫

👍 stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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@curation-cartel · Nov 19 '22

![1UP-PIZZA.png](https://files.peakd.com/file/peakd-hive/curation-cartel/23xediR4hotaNsS5pUJrmYVg3YGeTLpui41uCij2jhUDZ4uFT84zoGJf8a8VnfELXLJgt.png) |  <div class="phishy"><u><h4>You have received a __1UP__ from @gwajnberg!</h4></u></div> The @oneup-cartel will soon upvote you with:<hr> __@stem-curator, @pimp-curator, @vyb-curator, @pob-curator, @neoxag-curator, @fun-curator__ <hr>_And they will bring !PIZZA 🍕._
-|-

<sup>[Learn more](https://peakd.com/hive-102223/@flauwy/the-curation-cartel-1up-trigger-smart-voting-mana-and-high-delegation-returns-for-14-different-tribes) about our delegation service to earn daily rewards. Join the Cartel on [Discord](https://discord.gg/mvtAneE3Ca).</sup>

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@epic-fail · Nov 19 '22

$1.26

"I was checking some science news"

Just admit you were searching Leper & Armadillo Porn again, no need to be ashamed!

![untitled.gif](https://media.tenor.com/06BiLcVwlFEAAAAC/infested-colonist-starcraft2.gif)

👍 steemychicken1, trumpman, ruth-girl, giotists, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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@trumpman · Nov 19 '22

$0.10

🤫

👍 epic-fail, trumpybear, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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@fieryfootprints · Nov 19 '22

$0.43

> human so the microorganism may exhibit a totally different behavior on us

https://www.youtube.com/watch?v=DnBtoOAhba4

👍 steemychicken1, trumpman, ruth-girl, giotists, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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@trumpman · Nov 19 '22

😂😂😂😂😂😂

👍 stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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@gwajnberg · Nov 19 '22

Leprosy patients suffer a lot , they used to have lots of problems in society … hopefully they move forward with this research! But it is the first time that i saw using armadillo for health experiment model!
!1UP

<a href="https://discord.gg/zQrvxAu7mu">
<img src="https://files.peakd.com/file/peakd-hive/thecuriousfool/23wCNFDyCLJu1v77TTg2MYKkd7XWkgF9fhiLujTDAaLaUz7H4AaQkDentB5UMVS8FcrVs.png"></a>

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@olympicdragon · Nov 18 '22

$0.12

That's really interesting. Tissue regeneration is fascinating technology in science !

👍 steemychicken1, trumpman, ruth-girl, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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@pixresteemer · Nov 18 '22

<center>![pixresteemer_incognito_angel_mini.png](https://files.peakd.com/file/peakd-hive/pixresteemer/8h7BBw1w-pixresteemer_incognito_angel_mini.png)</center><center>Bang, I did it again... I just rehived your post!</center><center>Week 132 of my [contest](/hive-179017/@pixresteemer/the-re-hive-contest-results-week-131-and-start-week-132) just started...you can now check the winners of the previous week!</center><center><sub>4</sub></center>

👍 jhonathancor, irisenaaa, javierbasti, jodrmrjjjj, jacr, ikonikvu

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properties (23)vote details (6)

voter	weight	wgt%	rshares	pct	time
ikonikvu	0 B		0	100%
jacr	0 B		0	100%
jodrmrjjjj	0 B		0	100%
javierbasti	0 B		0	100%
irisenaaa	0 B		0	100%
jhonathancor	0 B		0	100%

@pizzabot · Nov 19 '22

<center>🍕 PIZZA !


I gifted <strong>$PIZZA</strong> slices here:
@curation-cartel<sub>(16/20)</sub> tipped @trumpman (x1)


<sub>Learn more at https://hive.pizza!</sub></center>

properties (22)

`author`	pizzabot
`permlink`	re-the-future-is-leper-20221119t164159z
`category`	hive-163521
`json_metadata`	"{"app": "beem/0.24.19"}"
`created`	2022-11-19 16:42:00
`last_update`	2022-11-19 16:42:00
`depth`	1
`children`	0
`last_payout`	2022-11-26 16:42:00
`cashout_time`	1969-12-31 23:59:59
`total_payout_value`	0.000 HBD
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`promoted`	0.000 HBD
`body_length`	178
`author_reputation`	6,135,286,204,089
`root_title`	"The future is leper!"
`beneficiaries`	`[]`
`max_accepted_payout`	1,000,000.000 HBD
`percent_hbd`	10,000
`post_id`	118,459,316
`net_rshares`	0

@seki1 · Nov 18 '22

$0.30

A liver transplant is about $600,000...
 Regrow liver to sell for transplants...
![untitled.gif](https://media.tenor.com/b5pwtufuf_YAAAAC/england-manager.gif)

👍 steemychicken1, trumpman, ruth-girl, stemgeeks, giotists, stemcuration, saboin.stem, yggdrasil.laguna

`author`	seki1
`permlink`	re-trumpman-rlkf3x
`category`	hive-163521
`json_metadata`	{"tags":["hive-163521"],"app":"peakd/2022.11.1"}
`created`	2022-11-18 22:43:12
`last_update`	2022-11-18 22:43:12
`depth`	1
`children`	1
`last_payout`	2022-11-25 22:43:12
`cashout_time`	1969-12-31 23:59:59
`total_payout_value`	0.151 HBD
`curator_payout_value`	0.150 HBD
`pending_payout_value`	0.000 HBD
`promoted`	0.000 HBD
`body_length`	158
`author_reputation`	76,600,290,787,885
`root_title`	"The future is leper!"
`beneficiaries`	`[]`
`max_accepted_payout`	1,000,000.000 HBD
`percent_hbd`	10,000
`post_id`	118,442,308
`net_rshares`	638,262,964,535
`author_curate_reward`	""

properties (23)vote details (8)

voter	rshares	pct
steemychicken1	330,905,425,735	12%
trumpman	247,968,418,423	12%
ruth-girl	57,241,961,516	12%
stemgeeks	1,120,805,388	6%
stemcuration	72,918,746	6%
yggdrasil.laguna	0	3%
saboin.stem	0	6%
giotists	953,434,727	12%

@trumpman · Nov 19 '22

Easy money

👍 stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

`author`	trumpman
`permlink`	re-seki1-rllngh
`category`	hive-163521
`json_metadata`	{"tags":["hive-163521"],"app":"peakd/2022.11.1"}
`created`	2022-11-19 14:41:06
`last_update`	2022-11-19 14:41:06
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`children`	0
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`cashout_time`	1969-12-31 23:59:59
`total_payout_value`	0.000 HBD
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`body_length`	10
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`root_title`	"The future is leper!"
`beneficiaries`	`[]`
`max_accepted_payout`	1,000,000.000 HBD
`percent_hbd`	10,000
`post_id`	118,456,804
`net_rshares`	1,256,950,236
`author_curate_reward`	""

properties (23)vote details (4)

voter	rshares	pct
stemgeeks	1,177,095,761	6%
stemcuration	79,854,475	6%
yggdrasil.laguna	0	3%
saboin.stem	0	6%

@steemychicken1 · Nov 18 '22

$0.15

Exploring ways to not die from drinking

👍 steemychicken1, trumpman, urun, ruth-girl, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

`author`	steemychicken1
`permlink`	re-trumpman-20221118t232038532z
`category`	hive-163521
`json_metadata`	{"tags":["hive-163521","pimp","neoxian","archon","proofofbrain","blog","fun","stem"],"app":"ecency/3.0.34-mobile","format":"markdown+html"}
`created`	2022-11-18 21:20:39
`last_update`	2022-11-18 21:20:39
`depth`	1
`children`	1
`last_payout`	2022-11-25 21:20:39
`cashout_time`	1969-12-31 23:59:59
`total_payout_value`	0.074 HBD
`curator_payout_value`	0.074 HBD
`pending_payout_value`	0.000 HBD
`promoted`	0.000 HBD
`body_length`	40
`author_reputation`	902,522,656,944,101
`root_title`	"The future is leper!"
`beneficiaries`	`[]`
`max_accepted_payout`	1,000,000.000 HBD
`percent_hbd`	10,000
`post_id`	118,440,570
`net_rshares`	316,809,459,764
`author_curate_reward`	""

properties (23)vote details (8)

voter	rshares	pct
steemychicken1	134,802,840,367	5%
trumpman	101,009,651,924	5%
ruth-girl	23,294,406,211	5%
stemgeeks	1,124,923,620	6%
stemcuration	73,351,104	6%
urun	56,504,286,538	100%
yggdrasil.laguna	0	3%
saboin.stem	0	6%

@trumpman · Nov 19 '22

$0.08

Exactly

👍 steemychicken1, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

`author`	trumpman
`permlink`	re-steemychicken1-rllni8
`category`	hive-163521
`json_metadata`	{"tags":["hive-163521"],"app":"peakd/2022.11.1"}
`created`	2022-11-19 14:42:09
`last_update`	2022-11-19 14:42:09
`depth`	2
`children`	0
`last_payout`	2022-11-26 14:42:09
`cashout_time`	1969-12-31 23:59:59
`total_payout_value`	0.038 HBD
`curator_payout_value`	0.038 HBD
`pending_payout_value`	0.000 HBD
`promoted`	0.000 HBD
`body_length`	7
`author_reputation`	1,540,821,120,311,618
`root_title`	"The future is leper!"
`beneficiaries`	`[]`
`max_accepted_payout`	1,000,000.000 HBD
`percent_hbd`	10,000
`post_id`	118,456,829
`net_rshares`	162,427,456,657
`author_curate_reward`	""

properties (23)vote details (5)

voter	rshares	pct
steemychicken1	161,167,252,971	6%
stemgeeks	1,180,036,999	6%
stemcuration	80,166,687	6%
yggdrasil.laguna	0	3%
saboin.stem	0	6%

@stemsocial · Nov 19 '22

re-trumpman-the-future-is-leper-20221119t191554645z

<div class='text-justify'> <div class='pull-left'>
 <img src='https://stem.openhive.network/images/stemsocialsupport7.png'> </div>

Thanks for your contribution to the <a href='/trending/hive-196387'>STEMsocial community</a>. Feel free to join us on <a href='https://discord.gg/9c7pKVD'>discord</a> to get to know the rest of us!

Please consider delegating to the @stemsocial account (85% of the curation rewards are returned).

You may also include @stemsocial as a beneficiary of the rewards of this post to get a stronger support.&nbsp;<br />&nbsp;<br />
</div>

properties (22)

`author`	stemsocial
`permlink`	re-trumpman-the-future-is-leper-20221119t191554645z
`category`	hive-163521
`json_metadata`	{"app":"STEMsocial"}
`created`	2022-11-19 19:15:54
`last_update`	2022-11-19 19:15:54
`depth`	1
`children`	0
`last_payout`	2022-11-26 19:15:54
`cashout_time`	1969-12-31 23:59:59
`total_payout_value`	0.000 HBD
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`pending_payout_value`	0.000 HBD
`promoted`	0.000 HBD
`body_length`	565
`author_reputation`	22,459,343,683,868
`root_title`	"The future is leper!"
`beneficiaries`	`[]`
`max_accepted_payout`	1,000,000.000 HBD
`percent_hbd`	10,000
`post_id`	118,462,862
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@urun · Nov 19 '22

$0.13

![1](https://pbs.twimg.com/media/Fh4f38TXgAEnjYK?format=jpg&name=small)


Hmmmmmmm

That's new

Drinking every day makes me stronger!

👍 steemychicken1, trumpman, ruth-girl, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

`author`	urun
`permlink`	re-trumpman-rlktyd
`category`	hive-163521
`json_metadata`	{"tags":["hive-163521"],"app":"peakd/2022.11.1"}
`created`	2022-11-19 04:03:48
`last_update`	2022-11-19 04:03:48
`depth`	1
`children`	1
`last_payout`	2022-11-26 04:03:48
`cashout_time`	1969-12-31 23:59:59
`total_payout_value`	0.064 HBD
`curator_payout_value`	0.064 HBD
`pending_payout_value`	0.000 HBD
`promoted`	0.000 HBD
`body_length`	133
`author_reputation`	93,309,388,768,828
`root_title`	"The future is leper!"
`beneficiaries`	`[]`
`max_accepted_payout`	1,000,000.000 HBD
`percent_hbd`	10,000
`post_id`	118,447,257
`net_rshares`	271,789,965,684
`author_curate_reward`	""

properties (23)vote details (7)

voter	rshares	pct
steemychicken1	140,749,714,352	5%
trumpman	105,465,650,774	5%
ruth-girl	24,324,131,803	5%
stemgeeks	1,171,234,431	6%
stemcuration	79,234,324	6%
yggdrasil.laguna	0	3%
saboin.stem	0	6%

@trumpman · Nov 19 '22

$0.03

Lol

👍 urun, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

`author`	trumpman
`permlink`	re-urun-rllncj
`category`	hive-163521
`json_metadata`	{"tags":["hive-163521"],"app":"peakd/2022.11.1"}
`created`	2022-11-19 14:38:42
`last_update`	2022-11-19 14:38:42
`depth`	2
`children`	0
`last_payout`	2022-11-26 14:38:42
`cashout_time`	1969-12-31 23:59:59
`total_payout_value`	0.014 HBD
`curator_payout_value`	0.014 HBD
`pending_payout_value`	0.000 HBD
`promoted`	0.000 HBD
`body_length`	3
`author_reputation`	1,540,821,120,311,618
`root_title`	"The future is leper!"
`beneficiaries`	`[]`
`max_accepted_payout`	1,000,000.000 HBD
`percent_hbd`	10,000
`post_id`	118,456,758
`net_rshares`	61,586,821,670
`author_curate_reward`	""

properties (23)vote details (5)

voter	rshares	pct
stemgeeks	1,169,768,949	6%
stemcuration	79,079,243	6%
urun	60,337,973,478	100%
yggdrasil.laguna	0	3%
saboin.stem	0	6%

@yeckingo1 · Nov 18 '22

$0.12

But the liver does not regenerate itself? Another drunken scientist report!

👍 steemychicken1, trumpman, ruth-girl, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

`author`	yeckingo1
`permlink`	re-trumpman-20221118t23640634z
`category`	hive-163521
`json_metadata`	{"tags":["pimp","neoxian","archon","proofofbrain","blog","fun","stem"],"app":"ecency/3.0.28-vision","format":"markdown+html"}
`created`	2022-11-18 22:06:39
`last_update`	2022-11-18 22:06:39
`depth`	1
`children`	1
`last_payout`	2022-11-25 22:06:39
`cashout_time`	1969-12-31 23:59:59
`total_payout_value`	0.060 HBD
`curator_payout_value`	0.060 HBD
`pending_payout_value`	0.000 HBD
`promoted`	0.000 HBD
`body_length`	75
`author_reputation`	133,661,889,265,838
`root_title`	"The future is leper!"
`beneficiaries`	`[]`
`max_accepted_payout`	1,000,000.000 HBD
`percent_hbd`	10,000
`post_id`	118,441,586
`net_rshares`	259,541,620,638
`author_curate_reward`	""

properties (23)vote details (7)

voter	rshares	pct
steemychicken1	134,406,490,811	5%
trumpman	100,712,602,343	5%
ruth-girl	23,225,767,882	5%
stemgeeks	1,123,552,452	6%
stemcuration	73,207,150	6%
yggdrasil.laguna	0	3%
saboin.stem	0	6%

@trumpman · Nov 19 '22

No idea, me not a liver expert!

👍 stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

`author`	trumpman
`permlink`	re-yeckingo1-rllnj3
`category`	hive-163521
`json_metadata`	{"tags":["hive-163521"],"app":"peakd/2022.11.1"}
`created`	2022-11-19 14:42:39
`last_update`	2022-11-19 14:42:39
`depth`	2
`children`	0
`last_payout`	2022-11-26 14:42:39
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`total_payout_value`	0.000 HBD
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`body_length`	31
`author_reputation`	1,540,821,120,311,618
`root_title`	"The future is leper!"
`beneficiaries`	`[]`
`max_accepted_payout`	1,000,000.000 HBD
`percent_hbd`	10,000
`post_id`	118,456,839
`net_rshares`	1,255,322,912
`author_curate_reward`	""

properties (23)vote details (4)

voter	rshares	pct
stemgeeks	1,175,623,246	6%
stemcuration	79,699,666	6%
yggdrasil.laguna	0	3%
saboin.stem	0	6%