transactions | 0. | ref_block_num | 5,541 |
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id | sm_submit_team |
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id | sm_submit_team |
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id | sm_find_match |
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memo | "Daily delegation reward from @dustsweeper." |
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json | {"trx_id":"631f8fed7b59babe208eb825096cacaebe762ae9","team_hash":"d753a0d43fd6d531d2e1a9d49a247cfc","app":"splinterlands/0.7.101"} |
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json | {"trx_id":"60d25e496bd3dff033aeffce425e83aab2dbe020","summoner":"G1-49-EHZNJMA774","monsters":["G1-45-5VS56GGIS0","starter-52-hkY23","C3-131-0QM7Y5Q2OW","G1-51-4FYVG96Y2O","C3-215-243KN0R9SW"],"secret":"a8498c3304","app":"steemmonsters/0.7.89"} |
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json | {"trx_id":"221c3dc9f7424309ce3ca8c62317ed57d2ab004f","summoner":"starter-145-Qgtp9","monsters":["starter-140-2hOkp","starter-196-7zhvz","starter-139-YWlOX"],"secret":"0d5b2af25e","app":"steemmonsters/0.7.89"} |
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json | {"type":"quest","quest_id":"d55beac42ab083c0a4b0fb26e12bd66474b650c6","app":"steemmonsters/0.7.89"} |
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json | {"trx_id":"646934b8b79636a63293750a735d117fc80e6cb6","summoner":"C1-5-2NKXE1N6DS","monsters":["starter-162-uJ8wB","C3-247-45CZYODM68","C4-158-V2593MDNCW","C1-3-B8FCT6HKWG","C3-242-J8OY12N5ZK","C1-62-LNA0CLNKSG"],"secret":"pb8n4gTWsV","app":"splinterlands/0.7.101"} |
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---|
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json | {"trx_id":"36a00d170ee25d13593629f5e1dc04183731e12e","team_hash":"910d0b90bea51aeaf27e0ce1039f2f2a","app":"steemmonsters/0.7.89"} |
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parent_permlink | polish |
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author | leon112 |
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permlink | szczepionka-novavax-nvx-cov2373 |
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title | "Szczepionka Novavax NVX-CoV2373 jest istotnie różna" |
---|
body | "Śledzę rodzaje szczepionek antycovidowych, gdyż jestem codziennie psychicznie molestowany przez żonę zmuszającą mnie do deklaracji, że się zaszczepię.
Jak na razie *"CZEKAM"* na szczepionkę Novavax. Może kiedyś będzie w Polsce.
![szczepionki.jpg](https://images.hive.blog/DQmTpyySHihAYu41Q8AbfqYyAZH5FVG5a9i9LcB6taXfvdd/szczepionki.jpg)
*źródło: https://www.bbc.com/news/world-europe-56744474*
**Jest ona odmienna od dotychczas oferowanych w Polsce.**
NVX-CoV2373 to propozycja szczepionki opartej na białkach, opracowaną na podstawie sekwencji genetycznej SARS-CoV-2, wirusa wywołującego chorobę COVID-19. NVX-CoV2373 został stworzony przy użyciu technologii rekombinowanych nanocząsteczek firmy Novavax do generowania antygenu pochodzącego z białka koronaawirusa (S) i jest uzupełniony opatentowaną przez Novavax 'saponiną Matrix-M ™ w celu wzmocnienia odpowiedzi immunologicznej i stymulowania wysokiego poziomu przeciwciał neutralizujących. Adiuwant Matrix-M ™ oparty na saponinie wykazał silne i dobrze tolerowane działanie poprzez stymulację wejścia komórek prezentujących antygen do miejsca wstrzyknięcia i zwiększenie prezentacji antygenu w lokalnych węzłach chłonnych, wzmacniając odpowiedź immunologiczną. NVX-CoV2373 zawiera oczyszczony antygen białkowy i nie może ani replikować, ani powodować COVID-19. Do tej pory ponad 37 000 uczestników wzięło udział w czterech różnych badaniach klinicznych w pięciu krajach. NVX-CoV2373 jest obecnie oceniany w dwóch kluczowych badaniach III fazy: badaniu w Wielkiej Brytanii, które zakończyło się rejestracją w listopadzie oraz badaniu PREVENT-19 w USA i Meksyku, które rozpoczęło się w grudniu.
NVX-CoV2373 zawiera pełnowymiarowe, przedfuzoryczne białko szczytowe, wykonane przy użyciu technologii rekombinowanych nanocząsteczek firmy Novavax oraz opatentowanego przez firmę adiuwanta Matrix-M ™ na bazie saponiny. Oczyszczone białko jest kodowane przez sekwencję genetyczną wypustki (S) białka SARS-CoV-2 i jest wytwarzane w komórkach owadów.
„Zmniejszone o 60% ryzyko zachorowania na COVID-19 u zaszczepionych osób w RPA podkreśla wartość tej szczepionki w zapobieganiu chorobom wywołanym przez wysoce niepokojący wariant krążący obecnie w Afryka Południowa , który rozprzestrzenia się na całym świecie. To pierwsza szczepionka przeciwko COVID-19, na którą mamy teraz obiektywne dowody na to, że chroni przed wariantem dominującym w Afryce Południowej ”- mówi profesor. Shabir Maddi , Dyrektor wykonawczy jednostki badawczej ds. Badań szczepionek i chorób zakaźnych (VIDA) w Wits oraz główny badacz w badaniu szczepionek Novavax COVID-19 w Afryka Południowa . „Jestem zachęcony, aby to zobaczyć Novavax planuje natychmiastowe rozpoczęcie badań klinicznych nad szczepionką przeznaczoną specjalnie dla tego wariantu, która wraz z obecną szczepionką może stanowić kamień węgielny walki z COVID-19 ”.
Novavax zapoczątkował opracowywanie nowych konstruktów przeciwko pojawiającym się szczepom [- potrójny mutant, który zawiera trzy krytyczne mutacje w domenie wiążącej receptor (RBD) i wiele mutacji poza RBD] na początku stycznia i oczekuje, że w najbliższych dniach wybierze idealne kompozycje na szczepionkę przypominającą i / lub skojarzoną biwalentną szczepionkę dla nowych szczepów. Firma planuje rozpocząć testy kliniczne tych nowych szczepionek w drugim kwartale tego roku.
więcej o tej szczepionce https://ir.novavax.com/news-releases/news-release-details/novavax-covid-19-vaccine-demonstrates-893-efficacy-uk-phase-3&prev=search&pto=aue" |
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38. | ref_block_num | 5,526 |
---|
ref_block_prefix | 2,404,900,557 |
---|
expiration | 2021-04-16 23:09:27 |
---|
operations | 0. | 0. | transfer |
---|
1. | from | dustsweeper |
---|
to | antisocialist |
---|
amount | 0.025 HIVE |
---|
memo | "Daily delegation reward from @dustsweeper." |
---|
|
---|
|
---|
|
---|
extensions | [] |
---|
signatures | 0. | 1f59c9dda74f0fe2181074375820d41e38f8eb8753abc57804c4b6420f94a7efcc28f3c61f60152754ea5d3f77da408bd923ac7b9242e79d4da6afe223de8251c7 |
---|
|
---|
transaction_id | 606629e923c28278ecfbfda5bd50bc8988eb53c6 |
---|
block_num | 53,089,703 |
---|
transaction_num | 38 |
---|
|
---|
39. | ref_block_num | 5,525 |
---|
ref_block_prefix | 3,403,243,239 |
---|
expiration | 2021-04-16 23:16:24 |
---|
operations | 0. | 0. | custom_json |
---|
1. | required_auths | [] |
---|
required_posting_auths | |
---|
id | sm_claim_reward |
---|
json | {"type":"quest","quest_id":"5ccd22f66037f00b4e09ff15cbd9c17341e31591","app":"steemmonsters/0.7.89"} |
---|
|
---|
|
---|
|
---|
extensions | [] |
---|
signatures | 0. | 2020bd6afc86619651854480a43e970b44a746b49f8b970f0cb32c3f166e51f7982318e08c14bd687a93d7e52aa0dc502ac7ddf51849366629b6581bc3b1f4e7f5 |
---|
|
---|
transaction_id | 3095d71cedf3ec8bbc807cad6c32be5a30c7fdf1 |
---|
block_num | 53,089,703 |
---|
transaction_num | 39 |
---|
|
---|
40. | ref_block_num | 5,525 |
---|
ref_block_prefix | 3,403,243,239 |
---|
expiration | 2021-04-16 23:16:24 |
---|
operations | 0. | 0. | custom_json |
---|
1. | required_auths | [] |
---|
required_posting_auths | |
---|
id | sm_surrender |
---|
json | {"battle_queue_id":"4a8841bf5ebe130a76efa3879fe112c4e243d906","app":"steemmonsters/0.7.89"} |
---|
|
---|
|
---|
|
---|
extensions | [] |
---|
signatures | 0. | 20740e83241d59fcf2756c0ba6e40046c0edba921c37c693eb7935fd2d7a53b1603ca2dfd77d9098e7dc274dbf5497c0a43db3cd5eb1dd9d2046cf787bb347e1cd |
---|
|
---|
transaction_id | 6a1b77f8a33d51031c0c93326d4c363b0bd6bdbf |
---|
block_num | 53,089,703 |
---|
transaction_num | 40 |
---|
|
---|
|
---|