Sounds like my Cleo.  She was a tough, nasty bugger to everybody but me :)  I also had a German Shorthair and Cleo absolutely dominated that dog...  She got ringworm when she was young and we had to give her pills.  3 to 5 per day for a month.  I bled pretty freely until we figured out to grind the pill on a little piece of steak.  She'd lick the powder off before she ate the meat :)

Some dog breeds are pretty suited to being left alone.  Some aren't.  My Sam does OK (I don't leave him long) long as he has food and water.