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RE: Icosahedron by mikewick77

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· @mikewick77 · (edited)
snake & spider symbiont venom may be similar to ecoli bacteria chemical fermentation, but symbiont cannot replicate like normal bacteria within different species, because a symbiont not a free-living cell.

snake venom an identical symbiont manufacturers chemicals similar to e.coli.

Tobacco Mosaic Virus & Peptide Amphiphile make the same shape.

snake venom makes Peptide, Symbionts manufacture Peptides.

Peptide Amphiphile is a Natrual form of Hydrogel.

Peptide amphiphiles (PAs) are peptide-based molecules that self-assemble into supramolecular nanostructures including; spherical micelles, twisted ribbons, and high-aspect-ratio nanofibers.

Peptide Amphiphile

https://en.m.wikipedia.org/wiki/Peptide_amphiphile

Unusual Stability of Messenger RNA in Snake Venom Reveals Gene Expression Dynamics of Venom Replenishment

https://www.researchgate.net/publication/230645936_Unusual_Stability_of_Messenger_RNA_in_Snake_Venom_Reveals_Gene_Expression_Dynamics_of_Venom_Replenishment

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Endosymbiont 
Symbiont 
Peptide 
Cnidaria
Hydrozoa 
Scyphozoa

https://en.m.wikipedia.org/wiki/Cnidaria

Genome Mining Reveals Endopyrroles from a Nonribosomal Peptide Assembly Line Triggered in Fungal-Bacterial Symbiosis

https://pubmed.ncbi.nlm.nih.gov/31283172/

Proteomic characterisation of toxins isolated from nematocysts of the South Atlantic jellyfish Olindias sambaquiensis 

https://www.sciencedirect.com/science/article/abs/pii/S0041010113001839

Phylogenomics provides a robust topology of the major cnidarian lineages and insights on the origins of key organismal traits

https://bmcecolevol.biomedcentral.com/articles/10.1186/s12862-018-1142-0

Alternative mRNA Splicing in Three Venom Families Underlying a Possible Production of Divergent Venom Proteins of the Habu Snake, Protobothrops flavoviridis

https://www.mdpi.com/2072-6651/11/10/581/htm

The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system

https://www.pnas.org/doi/10.1073/pnas.1314702110

Like venom coursing through the body: Researchers identify mechanism driving COVID-19 mortality

https://www.sciencedaily.com/releases/2021/08/210824135358.htm

sPLA2-IIA enzyme destroys microbial cell membranes in bacterial infections, as well as its similar genetic ancestry with a key enzyme found in snake venom.

..

Antimicrobial Resistance in Escherichia coli

https://pubmed.ncbi.nlm.nih.gov/30003866/

The intracellular function of extracellular signaling peptides

https://pubmed.ncbi.nlm.nih.gov/11587781/

Evolution Mystery: Spider Venom And Bacteria Share Same Toxin

https://www.sciencedaily.com/releases/2006/02/060202075525.htm

There’s a Perfectly Good Reason to Mass-Produce Snake Venom

https://www.theatlantic.com/science/archive/2020/01/how-make-snake-venom-without-any-snakes/605347/

Glutathione and Transition-Metal Homeostasis in Escherichia coli

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493246/

Ascorbic acid metabolism and functions: A comparison of plants and mammals

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191929/

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Suppression of RNA Recognition by Toll-like Receptors: The Impact of Nucleoside Modification and the Evolutionary Origin of RNA

https://www.cell.com/immunity/fulltext/S1074-7613(05)00211-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1074761305002116%3Fshowall%3Dtrue

Penn’s mRNA scientists Drew Weissman and Katalin Karikó receive the 2021 Lasker Prize, the top US award in biomedical research

https://abigailgroffcom.b-cdn.net/penns-mrna-scientists-drew-weissman-and-katalin-kariko-receive-the-2021-lasker-prize-the-top-us-award-in-biomedical-research/

Matrix protein of rabies virus is responsible for the assembly and budding of bullet-shaped particles and interacts with the transmembrane spike glycoprotein G

https://pubmed.ncbi.nlm.nih.gov/9847327/

Designing Signal Peptides for Efficient Periplasmic Expression of Human Growth Hormone in Escherichia coli

https://pubmed.ncbi.nlm.nih.gov/28851205/

Thioredoxin-linked reductive inactivation of venom neurotoxins

https://pubmed.ncbi.nlm.nih.gov/8135548/

Bacterial ribonucleases and their roles in RNA metabolism

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776250/

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Mycoplasma spp. in captive snakes (Boa constrictor and Bothrops atrox) from Brazil

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Slime mold

https://en.m.wikipedia.org/wiki/Slime_mold

Slime molds begin life as amoeba -like cells. These unicellular amoebae are commonly haploid and feed on bacteria. These amoebae can mate if they encounter the correct mating type and form zygotes that then grow into plasmodia. These contain many nuclei without cell membranes between them.
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@mikewick77 · (edited)
![Plot-of-synteny-between-the-genomes-of-Ca-Rickettsiella-viridis-and-R-grylli.png](https://images.hive.blog/DQmemznC74hXoRDpnWD5RYwQgXfLkXKuWf724pYhrwqbr5H/Plot-of-synteny-between-the-genomes-of-Ca-Rickettsiella-viridis-and-R-grylli.png)


Snake Venom 
Phosphodiesterase 
5’-nucleotidase
5’-mononucleotides
3’-OH-terminated 
riboand deoxyribo-oligonucleotides

https://www.innov-research.com/products/snake-venom-phosphodiesterase-i-purified-lyophilized

The enzyme has an optimal pH range of 9.8-10.4 and a molecular weight of 115 kDa. It is inhibited by reducing agents such as glutathione, cysteine and ascorbic acids and completely inhibited by 5 mM EDTA. ATP, ADP and AMP are partial inhibitors. The enzyme has an absolute requirement for Mg2+.

Source: 
Rattlesnake Venom
Storage Conditions: -20°C

..

Dynabeads 
Magnetic Beads
Thermo Fisher

https://www.thermofisher.com/us/en/home/brands/product-brand/dynal.html

..

https://en.m.wikipedia.org/wiki/Phosphodiesterase

https://en.m.wikipedia.org/wiki/D-dimer

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Botox is a drug made from a toxin produced by the bacterium Clostridium botulinum.

Snake venom is used as a wrinkle-reducing treatment, but it is supposed to be put in a cream that's used on the surface of the skin.

cone snail venom, Botox alternative, Also called snail venom conopeptide or MU-conotoxin, this synthetic ingredient mimics the effects of cone snail venom.

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Genetic engineering and biological weapons

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326447/

USSR 'invisible anthrax', resulting from the introduction of an alien gene into Bacillus anthracis that altered its immunological properties. Existing vaccines proved to be ineffective against this new genetically engineered strain.

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MRSA
Superantigen

https://en.m.wikipedia.org/wiki/Superantigen

https://en.m.wikipedia.org/wiki/Staphylococcus_aureus

https://www.microscopemaster.com/alphaproteobacteria.html

Recently Evolved Francisella-Like Endosymbiont Outcompetes an Ancient and Evolutionarily Associated Coxiella-Like Endosymbiont in the Lone Star Tick (Amblyomma americanum) Linked to the Alpha-Gal Syndrome

https://www.frontiersin.org/articles/10.3389/fcimb.2022.787209/full

Which bacterium is the ancestor of the animal mitochondrial genome?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC45536/

Mimicking Human Brain Development Using Organoids

https://www.news-medical.net/news/20180907/Mimicking-Human-Brain-Development-Using-Organoids.aspx

Organoids of Human Endometrium: A Powerful In Vitro Model for the Endometrium-Embryo Cross-Talk at the Implantation Site

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291023/

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they are blending chimera Organoids with humans & calling it medicine, this is gain of function.

Organoid cells are unusual, immortal cell line hela, hydra ect.. stem cells.

reminds me of endosymbionts & symbiogenesis of bacteria into biological cells, aka chimera viruses is the chimera organoid cell line code, venom acts as the alkaloid.
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