json_metadata | "{"app":"musing/1.1","appTags":["Question"],"appCategory":"Question","appTitle":"What causes down syndrome?","appBody":"<p>In most cases, Down Syndrome is caused by an extra chromosome. Specifically, a third copy of chromosome 21. In a normal healthy baby, there are two copies of each chromosome but the majority (95%) of children born with down syndrome have a third copy of chromosome 21. </p>\n<p>In rare cases, it is caused by a partial copy of that same chromosome in some cells but not all. This form is so rare it seen in only 1 out of 50 cases of the disease. This rare form is called Mosaic Down Syndrome. I'm sure you can deduce how this form gets its name.</p>\n<p>Down syndrome is not hereditary and its cause is literally a game of chance. If you think about the amount of cell division that leads to a human child it is a miracle when each child is born. Down syndrome is simply a single mistake in the billions of cell divisions that occur prior to a fully formed human.</p>\n<p>The main risk factor is the age of the mother. After the age of 30 a mother's chance of giving birth decreases substantially and her chance of conceiving a child with the disorder increases. </p>","appDepth":2,"appParentPermlink":"fks4f6zsw","appParentAuthor":"mosinusita","musingAppId":"aU2p3C3a8N","musingAppVersion":"1.1","musingPostType":"answer"}" |
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