My question is based on this blog article from https://deepmind.com/blog/alphafold/ . The Google Deepmind Team have won the "Community Wide Experiment on the Critical Assessment of Techniques for Protein Structure Prediction" (CASP) **protein folding contest**. The contest is to find protein structure from amino acid sequence. The results as per this website seems great: http://predictioncenter.org/casp13/zscores_final.cgi?formula=assessors.  *Snapshot from [CASP website](http://predictioncenter.org/casp13/zscores_final.cgi?formula=assessors)* Note the zscore of A7D team(Google's team code). It is 62.27 And see the second position score: 42.89! See the difference! So my question is this: **What are the implications of Google Deepmind Alphafold team winning protein folding contest?** Will the [protein-folding problem](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443096/) be solvable in near future? **Ref:** - [Dill, Ken A., et al. "The protein folding problem." Annu. Rev. Biophys. 37 (2008): 289-316.](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443096/) - https://deepmind.com/blog/alphafold/ **StemQ Notice:** *This post was originally submitted on [StemQ.io](http://www.stemq.io), a Q&A application for STEM subjects powered by the Steem blockchain.*
author | dexterdev |
---|---|
permlink | what-are-the-implications-of-google-deepmind-alphafold-team-winning-protein-folding-contest |
category | stemq |
json_metadata | {"tags":["stemq","Biology","steemstem","protein-folding"],"app":"StemQ/0.1.2"} |
created | 2018-12-03 17:53:09 |
last_update | 2018-12-03 17:53:09 |
depth | 0 |
children | 2 |
last_payout | 2018-12-10 17:53:09 |
cashout_time | 1969-12-31 23:59:59 |
total_payout_value | 0.835 HBD |
curator_payout_value | 0.211 HBD |
pending_payout_value | 0.000 HBD |
promoted | 0.000 HBD |
body_length | 1,315 |
author_reputation | 17,771,704,061,240 |
root_title | "What are the implications of Google Deepmind Alphafold team winning protein folding contest?" |
beneficiaries | [] |
max_accepted_payout | 1,000,000.000 HBD |
percent_hbd | 10,000 |
post_id | 76,305,386 |
net_rshares | 1,806,920,248,477 |
author_curate_reward | "" |
voter | weight | wgt% | rshares | pct | time |
---|---|---|---|---|---|
wackou | 0 | 20,061,370,822 | 0.32% | ||
lafona-miner | 0 | 182,850,833,758 | 5% | ||
tombstone | 0 | 89,052,758,394 | 0.4% | ||
kevinwong | 0 | 75,577,286,373 | 1% | ||
eric-boucher | 0 | 1,730,291,786 | 0.54% | ||
anwenbaumeister | 0 | 10,651,629 | 1.08% | ||
mammasitta | 0 | 209,390,287 | 0.05% | ||
mrwang | 0 | 60,678,534 | 0.5% | ||
liberosist | 0 | 2,795,612,914 | 1.08% | ||
arconite | 0 | 253,534,940 | 0.5% | ||
steemeat | 0 | 201,275,138 | 100% | ||
misha | 0 | 5,236,360,708 | 100% | ||
lemouth | 0 | 21,191,486,909 | 3.75% | ||
matildapurse | 0 | 2,163,023,680 | 25% | ||
rwilday | 0 | 52,824,750 | 100% | ||
lamouthe | 0 | 2,183,772,368 | 5% | ||
lk666 | 0 | 93,917,506 | 0.54% | ||
curie | 0 | 29,076,951,326 | 1.08% | ||
hendrikdegrote | 0 | 506,382,865,782 | 1.08% | ||
vact | 0 | 20,106,995,541 | 1.08% | ||
golbang | 0 | 2,611,826,391 | 0.32% | ||
steemstem | 0 | 186,834,674,167 | 5% | ||
dna-replication | 0 | 1,313,973,719 | 5% | ||
moksamol | 0 | 88,344,899 | 0.54% | ||
bloom | 0 | 20,672,038,887 | 5% | ||
iansart | 0 | 636,072,998 | 0.54% | ||
khussan | 0 | 577,363,830 | 100% | ||
kryzsec | 0 | 2,127,052,409 | 4% | ||
helo | 0 | 1,092,357,017 | 2.5% | ||
samminator | 0 | 1,477,589,390 | 2.5% | ||
locikll | 0 | 377,738,639 | 2.16% | ||
mahdiyari | 0 | 3,786,216,863 | 2.5% | ||
lorenzor | 0 | 4,639,870,022 | 50% | ||
aboutyourbiz | 0 | 164,146,816 | 1.08% | ||
alexander.alexis | 0 | 1,911,851,650 | 5% | ||
suesa | 0 | 115,805,559,188 | 25% | ||
cryptokrieg | 0 | 82,774,942 | 1.08% | ||
corsica | 0 | 2,135,366,773 | 5% | ||
fancybrothers | 0 | 500,520,136 | 1.5% | ||
howo | 0 | 6,981,395,107 | 2.5% | ||
tsoldovieri | 0 | 235,854,894 | 2.5% | ||
nitego | 0 | 84,234,069 | 0.32% | ||
neumannsalva | 0 | 109,428,471 | 0.54% | ||
wargof | 0 | 290,321,883 | 10% | ||
abigail-dantes | 0 | 80,977,185,116 | 5% | ||
zonguin | 0 | 118,751,536 | 1.25% | ||
alexzicky | 0 | 822,246,156 | 1.25% | ||
mountain.phil28 | 0 | 3,559,180,642 | 25% | ||
iamphysical | 0 | 15,248,853,383 | 90% | ||
zest | 0 | 919,393,724 | 2.5% | ||
felixrodriguez | 0 | 158,852,171 | 2.5% | ||
azulear | 0 | 2,676,659,191 | 100% | ||
psicoluigi | 0 | 323,431,840 | 50% | ||
massivevibration | 0 | 3,473,077,981 | 5% | ||
nurhayati | 0 | 136,798,772 | 0.5% | ||
fbslo | 0 | 144,520,206 | 0.5% | ||
accelerator | 0 | 20,581,594,677 | 1.5% | ||
nicola71 | 0 | 296,931,091 | 0.87% | ||
espoem | 0 | 1,596,507,071 | 1% | ||
erikkun28 | 0 | 0 | 1% | ||
mayowadavid | 0 | 146,254,375 | 2.5% | ||
emdesan | 0 | 134,990,098 | 10% | ||
peaceandwar | 0 | 107,716,499 | 0.54% | ||
enzor | 0 | 100,042,145 | 5% | ||
jesusj1 | 0 | 77,912,022 | 100% | ||
carloserp-2000 | 0 | 36,781,622,968 | 100% | ||
gra | 0 | 1,778,444,839 | 5% | ||
drmake | 0 | 542,258,556 | 0.54% | ||
guga34 | 0 | 80,618,184 | 3.75% | ||
amestyj | 0 | 1,777,809,122 | 50% | ||
woolnami | 0 | 676,011,181 | 0.32% | ||
kenadis | 0 | 1,099,805,046 | 5% | ||
funtraveller | 0 | 2,027,477,673 | 0.2% | ||
gentleshaid | 0 | 4,357,311,111 | 10% | ||
ivymalifred | 0 | 1,096,691,192 | 50% | ||
sco | 0 | 3,636,445,772 | 4.5% | ||
ennyta | 0 | 1,870,982,989 | 50% | ||
rharphelle | 0 | 1,022,586,306 | 25% | ||
stahlberg | 0 | 136,460,405 | 0.54% | ||
vjap55 | 0 | 351,128,062 | 100% | ||
monie | 0 | 376,401,415 | 100% | ||
mangoish | 0 | 87,416,994 | 10% | ||
langford | 0 | 326,805,954 | 5% | ||
mathowl | 0 | 31,567,777,564 | 100% | ||
silkroadgo | 0 | 1,454,979,271 | 0.32% | ||
terrylovejoy | 0 | 730,005,049 | 2% | ||
thabiggdogg | 0 | 103,940,175 | 0.54% | ||
traviseric | 0 | 235,136,561 | 50% | ||
yrmaleza | 0 | 933,970,583 | 50% | ||
mondodidave73 | 0 | 276,315,052 | 0.75% | ||
kingabesh | 0 | 109,938,277 | 2.5% | ||
miguelangel2801 | 0 | 772,847,507 | 50% | ||
didic | 0 | 450,920,439 | 0.54% | ||
wdoutjah | 0 | 178,186,673 | 7.5% | ||
emiliomoron | 0 | 1,763,323,578 | 50% | ||
dexterdev | 0 | 235,088,956 | 2.5% | ||
nwjordan | 0 | 102,012,318 | 1.08% | ||
oghie | 0 | 480,638,417 | 50% | ||
robertbira | 0 | 468,412,868 | 1.25% | ||
bearded-benjamin | 0 | 22,270,460,236 | 50% | ||
alexdory | 0 | 1,894,267,037 | 2% | ||
benleemusic | 0 | 155,487,223 | 0.1% | ||
lianaakobian | 0 | 517,192,601 | 5% | ||
ulisesfl17 | 0 | 2,172,018,156 | 100% | ||
arac | 0 | 1,068,856,462 | 100% | ||
francostem | 0 | 610,255,935 | 5% | ||
ivan-g | 0 | 74,359,927 | 0.54% | ||
croctopus | 0 | 1,400,787,753 | 100% | ||
sissyjill | 0 | 71,643,008 | 7% | ||
deusjudo | 0 | 189,070,086 | 0.87% | ||
buaan | 0 | 749,938,952 | 100% | ||
emmanuel293 | 0 | 99,606,433 | 25% | ||
morbyjohn | 0 | 125,789,482 | 7% | ||
positiveninja | 0 | 95,280,383 | 0.54% | ||
tomastonyperez | 0 | 5,481,076,676 | 50% | ||
elvigia | 0 | 5,084,885,606 | 50% | ||
lesmouths-travel | 0 | 221,844,689 | 3.75% | ||
effofex | 0 | 98,387,718 | 0.75% | ||
luiscd8a | 0 | 2,052,286,526 | 80% | ||
eniolw | 0 | 2,122,279,418 | 50% | ||
de-stem | 0 | 3,156,791,523 | 4.95% | ||
geadriana | 0 | 913,652,517 | 50% | ||
elpdl | 0 | 494,204,754 | 100% | ||
derbesserwisser | 0 | 20,238,783,450 | 100% | ||
serylt | 0 | 1,461,431,019 | 4.9% | ||
josedelacruz | 0 | 2,810,185,803 | 50% | ||
joseangelvs | 0 | 1,094,376,818 | 100% | ||
viannis | 0 | 1,894,124,813 | 50% | ||
flores39 | 0 | 491,855,392 | 100% | ||
majapesi | 0 | 245,211,186 | 50% | ||
kendallron | 0 | 215,058,768 | 15% | ||
erickyoussif | 0 | 3,677,035,545 | 100% | ||
irelandscape | 0 | 6,490,106,556 | 40% | ||
deholt | 0 | 128,739,431 | 5% | ||
annekevb | 0 | 3,903,010,118 | 100% | ||
indayclara | 0 | 243,033,218 | 7.5% | ||
ifeoluwa88 | 0 | 762,738,653 | 20% | ||
temitayo-pelumi | 0 | 320,921,786 | 5% | ||
yusvelasquez | 0 | 425,708,898 | 50% | ||
alexworld | 0 | 433,516,219 | 25% | ||
frost1903 | 0 | 47,441,487 | 50% | ||
metama | 0 | 204,635,663 | 0.54% | ||
acont | 0 | 243,542,205 | 50% | ||
anaestrada12 | 0 | 8,109,819,950 | 100% | ||
steemzeiger | 0 | 221,743,657 | 4.95% | ||
juliocaraballo | 0 | 65,536,121 | 50% | ||
biomimi | 0 | 188,102,234 | 40% | ||
drsensor | 0 | 576,403,898 | 3% | ||
reyvaj | 0 | 777,089,398 | 2.5% | ||
jesusfl17 | 0 | 490,785,437 | 100% | ||
emsonic | 0 | 252,172,903 | 0.54% | ||
yomismosoy | 0 | 176,736,303 | 50% | ||
bestofph | 0 | 5,817,778,363 | 15% | ||
call-me-howie | 0 | 339,736,304 | 0.54% | ||
mary11 | 0 | 337,054,911 | 75% | ||
wstanley226 | 0 | 1,915,065,004 | 50% | ||
gpcx86 | 0 | 1,824,735,102 | 25% | ||
reinaseq | 0 | 1,972,338,532 | 70% | ||
suasteguimichel | 0 | 66,691,127 | 50% | ||
osariemen | 0 | 1,405,602,445 | 90% | ||
astromaniac | 0 | 2,792,138,231 | 100% | ||
fran.frey | 0 | 1,779,720,858 | 50% | ||
grouseunhelpful | 0 | 484,671,831 | 100% | ||
jrevilla | 0 | 153,237,131 | 50% | ||
alfonzoasdrubal | 0 | 548,795,248 | 100% | ||
stem-espanol | 0 | 34,579,367,774 | 100% | ||
praditya | 0 | 601,437,993 | 24% | ||
yashshah991 | 0 | 66,706,435 | 50% | ||
fanta-steem | 0 | 1,917,338,564 | 30% | ||
xeliram | 0 | 243,429,360 | 50% | ||
giulyfarci52 | 0 | 316,094,972 | 50% | ||
eu-id | 0 | 2,455,642,719 | 10% | ||
nfc | 0 | 31,171,669,807 | 3% | ||
stem.witness | 0 | 1,007,493,425 | 5% | ||
double-negative | 0 | 191,213,078 | 20% | ||
wilmer14molina | 0 | 145,423,432 | 10% | ||
bitok.xyz | 0 | 43,671,778,383 | 5% | ||
kingnosa | 0 | 49,739,775 | 50% | ||
whitebot | 0 | 18,739,207,263 | 1% | ||
amin-ove | 0 | 85,319,794 | 50% | ||
hairgistix | 0 | 149,566,596 | 0.54% | ||
hanyseek | 0 | 3,438,064 | 25% | ||
steemmyphoto | 0 | 1,458,419,868 | 100% |
<center>[](http://steemitboard.com/@dexterdev) **Congratulations @dexterdev**! You raised your level and are now a **Minnow**!</center> **Do not miss the last post from @steemitboard:** <table><tr><td><a href="https://steemit.com/steemitboard/@steemitboard/5jrq2c-steemitboard-saint-nicholas-day"><img src="https://steemitimages.com/64x128/http://i.cubeupload.com/mGo2Zd.png"></a></td><td><a href="https://steemit.com/steemitboard/@steemitboard/5jrq2c-steemitboard-saint-nicholas-day">Saint Nicholas challenge for good boys and girls</a></td></tr></table> > Support [SteemitBoard's project](https://steemit.com/@steemitboard)! **[Vote for its witness](https://v2.steemconnect.com/sign/account-witness-vote?witness=steemitboard&approve=1)** and **get one more award**!
author | steemitboard |
---|---|
permlink | steemitboard-notify-dexterdev-20181205t134246000z |
category | stemq |
json_metadata | {"image":["https://steemitboard.com/img/notify.png"]} |
created | 2018-12-05 13:42:45 |
last_update | 2018-12-05 13:42:45 |
depth | 1 |
children | 0 |
last_payout | 2018-12-12 13:42:45 |
cashout_time | 1969-12-31 23:59:59 |
total_payout_value | 0.000 HBD |
curator_payout_value | 0.000 HBD |
pending_payout_value | 0.000 HBD |
promoted | 0.000 HBD |
body_length | 867 |
author_reputation | 38,975,615,169,260 |
root_title | "What are the implications of Google Deepmind Alphafold team winning protein folding contest?" |
beneficiaries | [] |
max_accepted_payout | 1,000,000.000 HBD |
percent_hbd | 10,000 |
post_id | 76,398,119 |
net_rshares | 0 |
<div class='text-justify'> <div class='pull-left'> <br /> <center> <img width='125' src='https://i.postimg.cc/9FwhnG3w/steemstem_curie.png'> </center> <br/> </div> <br /> <br /> This post has been voted on by the **SteemSTEM** curation team and voting trail in collaboration with **@curie**. <br /> If you appreciate the work we are doing then consider [voting](https://www.steemit.com/~witnesses) both projects for witness by selecting [**stem.witness**](https://steemconnect.com/sign/account_witness_vote?approve=1&witness=stem.witness) and [**curie**](https://steemconnect.com/sign/account_witness_vote?approve=1&witness=curie)! <br /> For additional information please join us on the [**SteemSTEM discord**]( https://discord.gg/BPARaqn) and to get to know the rest of the community! </div>
author | steemstem |
---|---|
permlink | re-dexterdev-what-are-the-implications-of-google-deepmind-alphafold-team-winning-protein-folding-contest-20181204t003808957z |
category | stemq |
json_metadata | {"app":"bloguable-bot"} |
created | 2018-12-04 00:38:12 |
last_update | 2018-12-04 00:38:12 |
depth | 1 |
children | 0 |
last_payout | 2018-12-11 00:38:12 |
cashout_time | 1969-12-31 23:59:59 |
total_payout_value | 0.000 HBD |
curator_payout_value | 0.000 HBD |
pending_payout_value | 0.000 HBD |
promoted | 0.000 HBD |
body_length | 800 |
author_reputation | 262,017,435,115,313 |
root_title | "What are the implications of Google Deepmind Alphafold team winning protein folding contest?" |
beneficiaries | [] |
max_accepted_payout | 1,000,000.000 HBD |
percent_hbd | 10,000 |
post_id | 76,320,014 |
net_rshares | 0 |