A Case of a Warthin Tumor by adamada.stem

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hive-163521 · @adamada.stem · Sep 30 '22

$10.83

A Case of a Warthin Tumor

These tumors are more common in males, smokers, and in the late adulthood. But this specimen came from a old woman, non-smoker in their retirement years. Arises in the parotid gland and a common benign tumor under the salivary gland neoplasm category. 


At Scanner view (40x)
<center>![Warthin's Tumor Scanner.png](https://files.peakd.com/file/peakd-hive/adamada/23u6LDQUP9rmwyzkDmGNmNrmAm9QQweL2awkS35StpXuFKUJaXwWLxEr7BufZteVywTV5.jpg)</center>

At Low Power View (100x)

Notice the distinct two layered oncocyte epithelium? 

These tumors can appear cystic which explains those spaces and the supporting stroma has extensive lymphocytic infiltrates. 

<center>![Warthin's Tumor LPF.png](https://files.peakd.com/file/peakd-hive/adamada/23uR7cU9jCfAqftB5ZVc3xazMzQobe4BBAUiZJbiwwreybRCVCzazR7XtDgece7KgirUV.jpg)</center>

At High Power View (400x)
<center>![Warthin's Tumor HPF.png](https://files.peakd.com/file/peakd-hive/adamada/23xLBJquGotp5EWuviSPKWbyp19K4Uu5uBczJopdGxBYZPBLHnxNMfgp4Qx16XM3SaUCY.jpg)</center>



The prominent features one needs to look for under the slide is a two layer lining of oncocytic cells supported by a lymphocyte rich stroma with occasional reactive germinal centers. 

Whenever the word oncocyte comes to mind, I just think of a round to polygonal cell with a large amount of pink (eosinophilic granular) cytoplasm with a central hyperchromatic nuclei and prominent nucleoli. Similar to how one can say "[clear cell](https://peakd.com/hive-163521/@adamada.stem/clear-cell-neoplasms-from-different-organ-of-origins)" find the morphologic features similar yet the disease is located on multiple parts of the body. 

Anyway, this one is benign and complete resection solves it. 

I remember the first time I've seen this under the microscope and said it looks exactly like how the textbooks shows it. This sort of thing can be simple consolations you got when you love your work but hate the grind. 

For the visual side of things, I think Warthin Tumor looks pretty under the scope and it's recognizable which makes this my favorite guess the tumor slide for rotating interns on our department. 

There's also a [pleomorphic adenoma](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478272/) proximal to this tumor as an incidental finding but I forgot to take a shot at it. 

If you made it this far reading, thank you for your time.

Posted with [STEMGeeks](https://stemgeeks.net)

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@arcange · Oct 1 '22

Dear @adamada.stem,<br>May I ask you to review and support the Dev Marketing Proposal (https://peakd.com/me/proposals/232) we presented on Conference Day 1 at HiveFest?<br>The campaign aims to onboard new application developers to grow our ecosystem. If you missed the presentation, you can watch it on [YouTube](https://youtu.be/MK-tlTw_ctY?t=41).<br>You cast your vote for the proposal on [Peakd](https://peakd.com/me/proposals/232), [Ecency](https://ecency.com/proposals/232), [Hive.blog](https://wallet.hive.blog/proposals) or [using HiveSigner](https://hivesigner.com/sign/update_proposal_votes?proposal_ids=%5B%22232%22%5D&approve=true).<br><br>Thank you!

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@curation-cartel · Sep 30 '22

![1UP-PIZZA.png](https://files.peakd.com/file/peakd-hive/curation-cartel/23xediR4hotaNsS5pUJrmYVg3YGeTLpui41uCij2jhUDZ4uFT84zoGJf8a8VnfELXLJgt.png) |  <div class="phishy"><u><h4>You have received a __1UP__ from @gwajnberg!</h4></u></div> The @oneup-cartel will soon upvote you with:<hr> __@stem-curator__ <hr>_And they will bring !PIZZA 🍕._
-|-

<sup>[Learn more](https://peakd.com/hive-102223/@flauwy/the-curation-cartel-1up-trigger-smart-voting-mana-and-high-delegation-returns-for-14-different-tribes) about our delegation service to earn daily rewards. Join the Cartel on [Discord](https://discord.gg/mvtAneE3Ca).</sup>

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@gwajnberg · Sep 30 '22

$0.04

Wow very rare in non smokers!!
!1UP
<a href="https://discord.gg/zQrvxAu7mu">
<img src="https://files.peakd.com/file/peakd-hive/thecuriousfool/23wCNFDyCLJu1v77TTg2MYKkd7XWkgF9fhiLujTDAaLaUz7H4AaQkDentB5UMVS8FcrVs.png"></a>

👍 adamada, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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@adamada · Sep 30 '22

Not really that rare but it's not common on non-smokers.

👍 stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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@nathen007 · Sep 30 '22

$0.05

I always find it incredible the number of different conditions the human body can develop. So many categories and sub categories like no two seemingly similar cases are the same.

I don't why I should be surprised , we are incredibly complex machines and I see daily, dealing with kids with various different presentations of ASD , LD and ADHD, that no two cases are alike.

Fascinating subject matter and excellently written as always. 

Wishing you a great weekend fella :-)

👍 adamada, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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@adamada · Sep 30 '22

$0.80

Thank you for taking the time to look. This gets even complicated at the molecular and genetic level where diseases in the future can be possibly diagnosed right before they even manifest. We are heading that route and it's going to be interesting to see how much of the population will express the disease vs dormant when those mutations have been detecting asymptomatic.

👍 bdvoter, bdvoter.cur, stemgeeks, zaku, stemcuration, saboin.stem, yggdrasil.laguna
👎 xbdvoter

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@nikv · Sep 30 '22

$0.06

For some reason that looks totally 3D or is it just your microscope?

👍 adamada, stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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@adamada · Sep 30 '22

Probably the differences in focus, the low power image has a brown spot that's blurry which indicates a debris or mounting substance in another layer. Same effect with macrophotography.

👍 stemgeeks, stemcuration, saboin.stem, yggdrasil.laguna

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@stemsocial · Oct 1 '22

re-adamadastem-a-case-of-a-warthin-tumor-20221001t033210058z

<div class='text-justify'> <div class='pull-left'>
 <img src='https://stem.openhive.network/images/stemsocialsupport7.png'> </div>

Thanks for your contribution to the <a href='/trending/hive-196387'>STEMsocial community</a>. Feel free to join us on <a href='https://discord.gg/9c7pKVD'>discord</a> to get to know the rest of us!

Please consider delegating to the @stemsocial account (85% of the curation rewards are returned).

You may also include @stemsocial as a beneficiary of the rewards of this post to get a stronger support.&nbsp;<br />&nbsp;<br />
</div>

properties (22)