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1. | parent_author | mikewick77 |
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parent_permlink | o |
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author | mikewick77 |
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permlink | sc5fkm |
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title | "" |
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body | "Neurotransmitter
Serotonin
B12
GABA
Dopamine
Folate
Methylation
Biosynthesis
Bioactivation
DNA Synthesis
B Vitamins
Thiamine
Niacin
Heterocyclic
Heterocycle
Heteroatom
Gene Mutation
Serine Metabolism
Serine Synthesis Pathway (SSP)
PHGDH Gene
MTHFR (gene)
Methyl / Folate
SAM Cycling
Lipid Metabolism
Triglyceride
B Vitamins and the Brain: Mechanisms, Dose and Efficacy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/
B Vitamins in the nervous system:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930825/
Folate and DNA Methylation:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262611/
..
PHGDH and its inhibitors for regulating cancer metabolism
Emerging evidence suggests that cancer metabolism is closely associated to the serine biosynthesis pathway (SSP), in which glycolytic intermediate 3-phosphoglycerate is converted to serine through a three-step enzymatic transformation. As the rate-limiting enzyme in the first step of SSP, phosphoglycerate dehydrogenase (PHGDH) is overexpressed in various diseases, especially in cancer.
..
MTHFR (gene)
Methylenetetrahydrofolate reductase deficiency
Methylenetetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene.
Methylenetetrahydrofolate reductase deficiency is the most common genetic cause of elevated serum levels of homocysteine (hyperhomocysteinemia). It is caused by genetic defects in MTHFR, which is an important enzyme in the methyl cycle.
..
Methylenetetrahydrofolate (MTHFR), the One-Carbon Cycle, and Cardiovascular Risks
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703276/
Allosteric inhibition of MTHFR prevents futile SAM cycling and maintains nucleotide pools in one-carbon metabolism
https://www.jbc.org/article/S0021-9258(17)50430-5/fulltext" |
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json | {"contractName":"tokens","contractAction":"transfer","contractPayload":{"symbol":"SCRAP","to":"scraptrader","quantity":"12.21284140","memo":""}} |
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json | {"version":"1.1","medium":"podcast","reason":"update","iris":["https://www.spreaker.com/show/4748835/episodes/feed"],"timestampNs":1713468331038775808,"sessionId":10695177247710743270} |
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1. | parent_author | vaynard86 |
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parent_permlink | re-lorddiablo-sc5kbr |
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author | lolzbot |
---|
permlink | re-re-lorddiablo-sc5kbr-20240418t192517z |
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title | "" |
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body | "<div class='pull-right'><center><img src="https://lolztoken.com/lolz.png"><br><a href="https://lolztoken.com">lolztoken.com</a></p><br><br><br><br></center></div><p><center><strong>I have kleptomania.<br>When it gets bad I have to take something for it.</strong><br><sub>Credit: <a href="https://peakd.com/@reddit">reddit</a></sub><br>@lorddiablo, I sent you an <a href="https://lolztoken.com">$LOLZ</a> on behalf of vaynard86<br><br>(4/10)<br>Farm <strong><a href='https://lolztoken.com'>LOLZ tokens</a></strong> when you <strong><a href='https://peakd.com/hive-155986/@lolztoken/earn-10percent-apr-on-hive-power-delegations-to-the-lolz-project'>Delegate Hive</a> or <a href='https://peakd.com/hive-155986/@lolztoken/introducing-lolz-defi-now-you'>Hive Tokens</a>.</strong><br>Click to delegate: <a href='https://hivesigner.com/sign/delegateVestingShares?delegator=&delegatee=lolzbot&vesting_shares=10%20HP'>10</a> - <a href='https://hivesigner.com/sign/delegateVestingShares?delegator=&delegatee=lolzbot&vesting_shares=20%20HP'>20</a> - <a href='https://hivesigner.com/sign/delegateVestingShares?delegator=&delegatee=lolzbot&vesting_shares=50%20HP'>50</a> - <a href='https://hivesigner.com/sign/delegateVestingShares?delegator=&delegatee=lolzbot&vesting_shares=100%20HP'>100</a> HP</center></p>" |
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json_metadata | "{"app": "beem/0.24.19"}" |
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id | sm_market_purchase |
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json | {"currency":"DEC","items":["2da8e085f88be5b54d2a1e146ab2fabc62c6fa63-0","1516ab9a225099d7d664ad4714657f9a2539e06d-0","d46af20e014297919f36c5d2d38c2de51b42111e-12","e7622db287bb76278792f2f778d2a6d784205b2d-15","c96006677cac9ddc8b056ac5cb961e70156cc9e6-19","bb00facaea1b9aaa34599099cdee8c04547b94d6-25","551c1601b199d723329f27c6d4b1ea4f163d9177-0","48531aa356cb7da48cd28da6e3f10a1be9703286-2","6dbad44d063bdb44c48b397128f8796a07bc8971-32","6db044093e02ad60c73076f3c3c684397166a7bb-8","3a789aca2c9cd1450c4e46c5f7806ed38b3e7880-39"],"price":10064.002,"app":"splinterlands/0.7.139","n":"8j2yWJvsAt"} |
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