Viewing a response to: @mikewick77/stxp3f
Regeneration Pathway Warburg Effect (Oncology) https://en.m.wikipedia.org/wiki/Warburg_effect_(oncology) https://en.m.wikipedia.org/wiki/Leptin Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways https://pmc.ncbi.nlm.nih.gov/articles/PMC6085345/ The Antitumor Potentials of Benzimidazole Anthelmintics as Repurposing Drugs https://pmc.ncbi.nlm.nih.gov/articles/PMC7458798/ .. Fenbendazole and SV40: Some research suggests that fenbendazole may have an anti-cancer effect, potentially by inhibiting the growth or spread of cells infected with SV40. N-acetylcysteine (NAC) solutions, like Acetadote, typically have a pH range of 6.0 to 7.5. This range ensures the solution is neither too acidic nor too alkaline. Researchers discover intake of FDA-approved drug modulates disease progression in Alzheimer’s disease model https://medicine.iu.edu/news/2022/03/niacin-alzheimers-research Niacin, a B vitamin, has shown promise in modulating microglial response and potentially attenuating amyloid-induced pathology in models of Alzheimer's disease, particularly through the activation of the niacin receptor HCAR2. .. Serotonin-Producing Neuroendocrine Tumors (NETs): In patients with serotonin-producing NETs, tryptophan and niacin can be deficient, as the tumors can divert tryptophan metabolism towards serotonin production. Carcinoid Syndrome: When NETs, particularly those in the gastrointestinal tract, release hormones like serotonin, they can cause carcinoid syndrome. Carcinoid Heart Disease: High levels of serotonin can also contribute to carcinoid heart disease, a condition characterized by fibrosis (scarring) of the heart valves, particularly on the right side of the heart. 5-HT & 5-HIAA 5-HIAA (5-hydroxyindoleacetic acid) is the primary metabolite of serotonin (5-HT), a neurotransmitter and hormone. 5-Hydroxyindoleacetic acid (5-HIAA) is a waste product in the urine that measures the body's serotonin levels. It's used to diagnose and monitor carcinoid tumors, a type of neuroendocrine tumor. 5-HIAA levels can also indicate other conditions, such as celiac disease, cystic fibrosis, and autism spectrum disorder. 5-HIAA a biomarker for inborn errors of metabolism, diseases of malabsorption, and psychiatric conditions. An increase in brain 5-HT contents appears to have an important part in the therapeutic activity of Niacin. Neurochemical results show a vital role of Niacin by inhibiting MAOs and increasing 5-HT levels. Simultaneously, Niacin reduces redox status by decreasing oxidative stress marker and increasing antioxidant enzyme is also in favor of its protective effect for reducing anxiety and enhancing exploratory activity. In-silico studies also recommend that Niacin instigated increase in 5-HT levels probably due to binding of Niacin with MAOs.
author | mikewick77 |
---|---|
permlink | su0qs5 |
category | intercellular |
json_metadata | {"app":"hiveblog/0.1","links":["https://en.m.wikipedia.org/wiki/Warburg_effect_"]} |
created | 2025-04-01 02:55:18 |
last_update | 2025-04-04 17:33:57 |
depth | 2 |
children | 0 |
last_payout | 2025-04-08 02:55:18 |
cashout_time | 1969-12-31 23:59:59 |
total_payout_value | 0.000 HBD |
curator_payout_value | 0.000 HBD |
pending_payout_value | 0.000 HBD |
promoted | 0.000 HBD |
body_length | 2,891 |
author_reputation | 545,063,717,246 |
root_title | "Intercellular Homeostasis" |
beneficiaries | [] |
max_accepted_payout | 1,000,000.000 HBD |
percent_hbd | 10,000 |
post_id | 141,810,978 |
net_rshares | 0 |