![20200805_190156.jpg](https://images.hive.blog/DQmejmgoBbg4ACLSrNJXShvbk1TjP8iTvTDMg6kY19Nxe4q/20200805_190156.jpg)


Smallest Organisms

https://en.m.wikipedia.org/wiki/Smallest_organisms

Dinitroanilines

Microtubule-targeting agents (MTAs), also known as microtubulebinding agents, microtubule-interfering drugs, anti-microtubule drugs, or simply microtubule poisons

Microtubule-Targeting Agents: Strategies To Hijack the Cytoskeleton

Microtubular cytoskeletons of parasitic protozoa

Microtubule-targeting agents and their impact on cancer treatment

https://www.sciencedirect.com/science/article/pii/S0171933520300145

https://en.m.wikipedia.org/wiki/Hydrogel_encapsulation_of_quantum_dots

..

going threw this old book..

Nutrition and Feeding Strategies in Protozoa Brenda Nisbet

found this.. these are aquatic, but it says they are the smallest Microsporidia & make spores.

spores make me think much smaller then parent host, small like like exosome mycoplasma or virus, potentially avain or airborn.

https://en.m.wikipedia.org/wiki/Microsporidia

Microsporidia are a group of spore-forming unicellular parasites. They were once considered protozoans or protists, but are now known to be fungi, or a sister group to fungi.

Microsporidia have the smallest known (nuclear) eukaryotic genomes. The parasitic lifestyle of microsporidia has led to a loss of many mitochondrial and Golgi genes, and even their ribosomal RNAs are reduced in size compared with those of most eukaryotes. 

Currently known microsporidial genomes are 2.5 to 11.6 Mb in size, encoding from 1,848 to 3,266 proteins which is in the same range as many bacteria.

(same size as bacteria, might be misidentified as bacteria?)

..

https://en.m.wikisource.org/wiki/1911_Encyclopædia_Britannica/Endospora

https://scialert.net/fulltextmobile/?doi=ajava.2012.842.850&org=10


![fig2-2k12-842-850.jpg](https://images.hive.blog/DQmSugktX5qTp8KL15qnqJmVUvR4JjuEYQ3aPCYBpuXhzwn/fig2-2k12-842-850.jpg)


![fig8-2k12-842-850.jpg](https://images.hive.blog/DQmW85ZmoQfDMJuG9iD8EJjS7ggpQ4spo3CJKUpftmW68MN/fig8-2k12-842-850.jpg)

Phenanthridine

https://en.m.wikipedia.org/wiki/Phenanthridine

https://en.m.wikipedia.org/wiki/Nitroimidazole

https://en.m.wikipedia.org/wiki/Endopeptidase

https://en.m.wikipedia.org/wiki/Pepsin

https://en.m.wikipedia.org/wiki/Pepstatin

https://en.m.wikipedia.org/wiki/Chlorambucil

Hemoglobin 
proteolytic systems 
falcipains 
cysteine proteases 
ubiquitin proteasomal system (UPS) 


..

Blocking Plasmodium falciparum development via dual inhibition of hemoglobin degradation and the ubiquitin proteasome system by MG132

https://pubmed.ncbi.nlm.nih.gov/24023882/

Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1166610/

..


![220px-Fdl17-9-grey.jpg](https://images.hive.blog/DQmdYbje3fNBJ8TdRYgoFM5DrrDDHMbh9jrs8N4UKH17MpW/220px-Fdl17-9-grey.jpg)


Myxozoa
Spore 10 μm

https://en.m.wikipedia.org/wiki/Myxozoa

https://en.m.wikipedia.org/wiki/Micrometre

https://en.m.wikipedia.org/wiki/Nanometre

https://en.m.wikipedia.org/wiki/Obligate_parasite

https://en.m.wikipedia.org/wiki/Intracellular_parasite

https://en.m.wikipedia.org/wiki/Apicomplexa

https://en.m.wikipedia.org/wiki/Polistes_atrimandibularis

Evasion of host defences

A number of obligate intracellular parasites have evolved mechanisms for evading their hosts' cellular defences, including the ability to survive in distinct cellular compartments.

One of the mechanisms that hosts employ in their attempt to reduce the replication and spread of pathogens is apoptosis (programmed cell death). 

Some obligate parasites have developed ways to suppress this phenomenon, for example Toxoplasma gondii although the mechanism is not yet fully understood.

..

im looking for something smaller the this.

Myxozoa
Spore 10 μm

similar to Microsporidia with Apicomplexa Toxoplasmosis

..

Nanometers (nm)

Marine Viruses 
40 nm - 400 nm 

Bacteria
1000 nm

Algae
5000 nm

Poliovirus
30 nm


![OSC_Microbio_01_03_sizes.jpg](https://images.hive.blog/DQmYXDGRdqN7tx2cFTuVLSWV2T24EfMxjh2BFfjgEXicRR5/OSC_Microbio_01_03_sizes.jpg)


![a355568f5b83289cb05bccd8e8db1c54--biology-infographic.jpg](https://images.hive.blog/DQmViMAkwAZfLoAhaBdZibNakoz3nhK26hycswxLYbCwtrY/a355568f5b83289cb05bccd8e8db1c54--biology-infographic.jpg)

![virus-size-structure-n.jpg](https://images.hive.blog/DQmSp5vHRcQFMcdbNx9zKYF9rg1vL5VcWkpv93wjZLUp4eV/virus-size-structure-n.jpg)

https://en.m.wikipedia.org/wiki/Poliovirus

..

Genitalium is flask-shaped (about 300 - 600 nm)

Pneumoniae is more elongated (about 100 - 1000 nm). 

Hundreds of mycoplasma species infect animals. Virus range in size from about 20 to 400 nanometres in diameter. 

Mycoplasma is bigger than Virus.

https://cronodon.com/BioTech/bacteria_mycoplasmas.html

https://www.microscopemaster.com/mycoplasmas.html

..

https://en.m.wikipedia.org/wiki/Mycoplasma

https://en.m.wikipedia.org/wiki/Mollicutes

..

https://www.microscopemaster.com/mycoplasmas.html

![mycoplasma.webp](https://images.hive.blog/DQmbH59EEXBphyWj9dncGV36Dem6j6LGQVcGyn7b3XcVME9/mycoplasma.webp)


![mycoplasma_pneumoniae-613x326.jpg](https://images.hive.blog/DQmf1mRYpMFfnR1GccMxqDuhK4PC81ziuWB1S2SV1yGebyy/mycoplasma_pneumoniae-613x326.jpg)


![54TLbcUcnRm4Bw8fmw3Y3ebiYW61dkW16qTycFmMN9YqPfiSGJiaPNKDqsuNJPjQFrTJXx8CJE25amkGG6mnA7YbtEARbH8usJiPtJkEX2DPLK8cSpYYyxFKhWyFN9y4ZjUGFDxfp.jpeg.jpg](https://images.hive.blog/DQmYxgbvzHRCBUNAYN7upkXhMFCqJz42fMdmwCdQhNeky5q/54TLbcUcnRm4Bw8fmw3Y3ebiYW61dkW16qTycFmMN9YqPfiSGJiaPNKDqsuNJPjQFrTJXx8CJE25amkGG6mnA7YbtEARbH8usJiPtJkEX2DPLK8cSpYYyxFKhWyFN9y4ZjUGFDxfp.jpeg.jpg)


![simple_complex-cell.jpg](https://images.hive.blog/DQmV8VZRKYkN9hmWXqr3GiRQCmv9p1x11B4U7joud5TWvdf/simple_complex-cell.jpg)

..

https://en.m.wikipedia.org/wiki/Mononegavirales

https://en.m.wikipedia.org/wiki/Hendra_virus

https://en.m.wikipedia.org/wiki/Henipavirus

https://en.m.wikipedia.org/wiki/Hydrozoa

https://en.m.wikipedia.org/wiki/Placozoa

https://en.m.wikipedia.org/wiki/Cnidaria

https://en.m.wikipedia.org/wiki/Polypodium_(animal)

https://en.m.wikipedia.org/wiki/Choanozoa

The field of embryogenesis uses the word syncytium to refer to the coenocytic blastoderm embryos of invertebrates.

https://en.m.wikipedia.org/wiki/Syncytium

https://en.m.wikipedia.org/wiki/Blastoderm